Oncology Clinical Trials in Middletown, NJ

As of July 2026, 176 paid clinical trials are recruiting for Oncology in Middletown, New Jersey. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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182 clinical trials for Oncology

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Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05424029·Recruiting·Listed Jun 2022

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A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

for Esophageal Cancer

Sites in Middletown, Basking Ridge +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06123338·Phase 2·Recruiting·Listed Nov 2023

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A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

for Multiple Myeloma

Drug: Daratumumab

Sites in Middletown, Basking Ridge +7 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06083922·Phase 2·Recruiting·Listed Oct 2023

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A Study of Lenvatinib, Pembrolizumab, and Fulvestrant in People With Breast Cancer

for Metastatic Breast Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06110793·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer

for Breast Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05412225·Phase 1·Recruiting·Listed Jun 2022

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A Study Comparing Perioperative Stress Reduction vs. Standard of Care in Ovarian Cancer (PRESERVE)

for Ovarian Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05429970·Recruiting·Listed Jun 2022

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Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

for Rectal Adenocarcinoma

Sites in Middletown, Basking Ridge +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT04165772·Phase 2·Recruiting·Listed Nov 2019

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A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC)

for Metastatic Renal Cell Carcinoma

Drug: Cabozantinib

Sites in Middletown, Basking Ridge +6 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06835972·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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Glioma Developmental and HyperActive Ras Tumor (DHART) Board

for Glioma

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05489783·Recruiting·Listed Aug 2022

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Study of Aerobic Training for People Receiving Treatment for Breast Cancer

for Breast Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05716893·Phase 2·Recruiting·Listed Feb 2023

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A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer

for Prostate Cancer

Sites in Middletown, Basking Ridge +10 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Male·Age: 18+

Code: NCT06457919·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer

for Endometrial Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05691010·EARLY_Phase 1·Recruiting·Listed Jan 2023

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A Study of Surgery and Radiotherapy in People With Breast Cancer

for Metastatic Breast Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07053085·Phase 2·Recruiting·Listed Jul 2025

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DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer

for Solid Tumor

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225088·Recruiting·Listed Nov 2025

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A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers

for Gastrointestinal Cancer

Sites in Middletown, Basking Ridge +6 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05789485·Phase 2·Recruiting·Listed Mar 2023

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A Study of Avutometinib and Defactinib in People With Thyroid Cancer

for Thyroid Cancer

Drug: Avutometinib

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06007924·Phase 2·Recruiting·Listed Aug 2023

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A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia

for Refractory Acute Myeloid Leukemia

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 1+

Code: NCT06017258·Phase 1·Recruiting·Listed Aug 2023

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A Study of Mosunetuzumab Alone or With Zanubrutinib in People With Follicular Lymphoma

for Follicular Lymphoma

Drug: Mosunetuzumab

Sites in Middletown, Basking Ridge +7 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05389293·Phase 2·Recruiting·Listed May 2022

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A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

for Lung Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05419076·Phase 2·Recruiting·Listed Jun 2022

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A Study of NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05851924·Phase 2·Recruiting·Listed May 2023

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A Study of Changes to Prostate Procedures

for Prostate Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Male·Age: 18+

Code: NCT06986083·Phase 3·Recruiting·Listed May 2025

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A Study of Neurocognitive Tests and Questionnaires for People With Head and Neck Cancer Who Are Undergoing Radiation Therapy

for Head and Neck Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18 - 89

Code: NCT05207098·Recruiting·Listed Jan 2022

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A Study of CRD3874-SI in People With Solid Tumors

for Sarcoma

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06021626·Phase 1·Recruiting·Listed Sep 2023

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A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

for Neuroblastoma

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: All ages

Code: NCT06057948·Phase 2·Recruiting·Listed Sep 2023

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A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer

for Rectal Cancer

Sites in Middletown, Montvale +4 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06637462·Recruiting·Listed Oct 2024

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A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

for Non Small Cell Lung Cancer

Sites in Middletown, Basking Ridge +7 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05657873·Phase 2·Recruiting·Listed Dec 2022

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A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

for Metastatic Breast Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06678269·Phase 1·Recruiting·Listed Nov 2024

Apply to this trial

A Study of Sacituzumab Govitecan in People With Mesothelioma

for Mesothelioma

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06477419·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

A Study of Sotorasib in People With Brain Tumors

for Brain Tumor

Drug: Sotorasib

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06807619·Phase 1·Recruiting·Listed Feb 2025

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A Study of Intra-operative Imaging in Women With Ovarian Cancer

for Ovarian Cancer

Sites in Middletown, Basking Ridge +7 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: All ages

Code: NCT04878094·Phase 3·Recruiting·Listed May 2021

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A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

for Metastatic Breast Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06246968·Phase 1·Recruiting·Listed Feb 2024

Apply to this trial

A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer

for Breast Cancer

Sites in Middletown, Basking Ridge +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05570253·Phase 2·Recruiting·Listed Oct 2022

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Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

for Sarcoma

Sites in Middletown, Basking Ridge +6 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06129903·Recruiting·Listed Nov 2023

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A Study of Blood Pressure Control During Cancer Treatment

for Breast Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT06023576·Phase 2·Recruiting·Listed Sep 2023

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A Study of Language Interpretation Solutions for People With Breast Cancer

for Breast Cancer

Sites in Middletown, Basking Ridge +6 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06721065·Recruiting·Listed Dec 2024

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A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

for Adenocarcinoma of the Rectum

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05672524·Phase 2·Recruiting·Listed Jan 2023

Apply to this trial

A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

for Urothelial Carcinoma

Sites in Middletown, Basking Ridge +6 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05868265·Phase 2·Recruiting·Listed May 2023

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A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change

for Metastatic Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05010031·Phase 2·Recruiting·Listed Aug 2021

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Lymphedema Surveillance Study

for Breast Cancer

Sites in Middletown, Basking Ridge +5 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT02743858·Recruiting·Listed Apr 2016

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A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

for Wilms Tumor

Drug: Selinexor

Sites in Middletown, Basking Ridge +14 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 12 Months+

Code: NCT05985161·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

Conditions in Oncology (Middletown, NJ)

Breast cancer· 28 Non-small cell lung cancer (NSCLC)· 20 Multiple myeloma· 14 Acute myeloid leukemia (AML)· 12 Metastatic breast cancer· 11 Prostate cancer· 9 Bladder cancer· 9 Solid tumor· 9 Endometrial cancer· 8 Kidney cancer· 7 Ovarian cancer· 7 Non-Hodgkin lymphoma· 7 Head and neck cancer· 7 Sarcoma· 7 Lung cancer· 6 Colorectal cancer· 6 Pancreatic cancer· 6 Glioma· 6 Melanoma· 6 Cancer (any)· 6 Rectal cancer· 4 Gastric cancer· 4 Triple-negative breast cancer· 3 Leukemia (other)· 3 Thyroid cancer· 3 HER2-positive breast cancer· 2 HER2-negative breast cancer· 2 Esophageal cancer· 2 Gastrointestinal cancer· 2 Fallopian tube cancer· 2 Acute lymphoblastic leukemia· 2 Myelodysplastic syndromes (MDS)· 2 Hodgkin lymphoma· 2 Diffuse large B-cell lymphoma (DLBCL)· 2 Follicular lymphoma· 2 Hematologic malignancy· 2 Osteosarcoma· 2 Mesothelioma· 2 Colon cancer· 1 Gastroesophageal junction cancer· 1 Metastatic prostate cancer· 1 Cervical cancer· 1 Gynecologic cancer· 1 Glioblastoma· 1 Brain cancer· 1 Brain metastases· 1 Chronic lymphocytic leukemia (CLL)· 1 Myelofibrosis· 1 Marginal zone lymphoma· 1 Small lymphocytic lymphoma· 1 Soft tissue sarcoma· 1 Neuroblastoma· 1