Clinical Trials at Medical College of Wisconsin

As of September 2026, 229 paid clinical trials are recruiting at Medical College of Wisconsin, located at Medical College of Wisconsin: Todd Wehr Library, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, phone (414) 456-8300 in Milwaukee, Wisconsin. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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230 clinical trials at Medical College of Wisconsin

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

Sites in Milwaukee, Madison +19 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting·Listed Jan 2025

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A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

for Multiple Sclerosis (MS) Primary Progressive

Sites in Milwaukee +17 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07067463·Phase 3·Recruiting·Listed Jul 2025

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Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for Treatment Resistant Depression

Sites in Milwaukee +24 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 22 - 70

Code: NCT06423430·Recruiting·Listed May 2024

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A Study of Navlimetostat (BMS-986504) Alone or in Combination With Izalontamab Brengitecan in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion or MTAP Loss (MountainTAP-9)

for Carcinoma, Non-Small-Cell Lung

Drug: Navlimetostat

Sites in Milwaukee +8 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06855771·Phase 2·Recruiting·Listed Mar 2025

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GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

for Aortic Dissection

Sites in Milwaukee +21 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06827990·Recruiting·Listed Feb 2025

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A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

for Relapsed/Refractory Multiple Myeloma

Drug: Daratumumab

Sites in Milwaukee, Madison +13 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT04973605·Phase 1, Phase 2·Recruiting·Listed Jul 2021

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A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

for B-cell Malignancy

Sites in Milwaukee, Madison +15 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06634589·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

for Multiple Sclerosis, Relapsing-Remitting

Sites in Milwaukee +8 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 10 - 17

Code: NCT06408259·Phase 3·Recruiting·Listed May 2024

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Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for Non-Hodgkin Lymphoma

Sites in Milwaukee +9 more locations

Sponsor: Imugene Limited

Sex: All·Age: 18+

Code: NCT03666000·Phase 1·Recruiting·Listed Sep 2018

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Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA

for Aortic Arch Aneurysm

Sites in Milwaukee +20 more locations

Sponsor: Artivion Inc.

Sex: All·Age: 18 - 80

Code: NCT07089576·Recruiting·Listed Jul 2025

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Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for Myelofibrosis

Sites in Milwaukee +25 more locations

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT05320198·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Sites in Milwaukee +11 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07008118·Phase 1·Recruiting·Listed Jun 2025

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Evaluate the Clinical Performance of the Flow Cytometry - FlowPath Lung Test as a Sensitive and Specific Non-invasive Diagnostic of Sputum Samples to Identify/Detect the Presence of Lung Cancer in High-risk Individuals Who Have Existing Lung Nodules, 6 to <30 mm in Diameter, Determined by LDCT.

for Lung Cancer (Diagnosis)

Sites in Milwaukee +10 more locations

Sponsor: bioAffinity Technologies Inc.

Sex: All·Age: 50 - 80

Code: NCT07168993·Recruiting·Listed Sep 2025

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A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

Sites in Milwaukee +16 more locations

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting·Listed Jan 2026

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A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Milwaukee +22 more locations

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting·Listed Aug 2024

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XTX301 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Milwaukee +9 more locations

Sponsor: Xilio Development, Inc.

Sex: All·Age: 18+

Code: NCT05684965·Phase 1, Phase 2·Recruiting·Listed Jan 2023

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A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

for Chronic Lymphocytic Leukemia (CLL)

Sites in Milwaukee +14 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05131022·Phase 1·Recruiting·Listed Nov 2021

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Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

for COPD

Sites in Milwaukee +9 more locations

Sponsor: Nuvaira, Inc.

Sex: All·Age: 40 - 80

Code: NCT07051707·Recruiting·Listed Jul 2025

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A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Milwaukee +12 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT05125016·Phase 1, Phase 2·Recruiting·Listed Nov 2021

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A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

for Phenylketonuria (PKU)

Sites in Milwaukee +11 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: All ages

Code: NCT05813678·Recruiting·Listed Apr 2023

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Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

for COPD

Sites in Milwaukee +17 more locations

Sponsor: Apreo Health, Inc.

Sex: All·Age: 40 - 84

Code: NCT06891755·Recruiting·Listed Mar 2025

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A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

for Chronic Lymphocytic Leukemia

Sites in Milwaukee +19 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06876649·Phase 4·Recruiting·Listed Mar 2025

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A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

for Chronic Lymphocytic Leukemia

Sites in Milwaukee +15 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06876662·Phase 4·Recruiting·Listed Mar 2025

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Study of SGR-1505 in Mature B-Cell Neoplasms

for Mature B-Cell Neoplasm

Sites in Milwaukee +15 more locations

Sponsor: Schrödinger, Inc.

Sex: All·Age: 18+

Code: NCT05544019·Phase 1·Recruiting·Listed Sep 2022

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A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

for Epilepsy, Temporal Lobe

Sites in Milwaukee +15 more locations

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06422923·Phase 1, Phase 2·Recruiting·Listed May 2024

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A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

for Breast Cancer

Drug: Ribociclib

Sites in Milwaukee +9 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07405801·Phase 2·Recruiting·Listed Feb 2026

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A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Milwaukee +20 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07277231·Phase 3·Recruiting·Listed Dec 2025

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A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Milwaukee +6 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07226349·Phase 1·Recruiting·Listed Nov 2025

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A Study of BGB-11417 in Participants With Myeloid Malignancies

for Acute Myeloid Leukemia

Sites in Milwaukee +3 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT04771130·Phase 1, Phase 2·Recruiting·Listed Feb 2021

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A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

for Small Cell Lung Cancer

Drug: Gocatamig

Sites in Milwaukee +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06780137·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study

for Relapsing Remitting Multiple Sclerosis

Sites in Milwaukee +8 more locations

Sponsor: SetPoint Medical Corporation

Sex: All·Age: 22 - 60

Code: NCT06796504·Recruiting·Listed Jan 2025

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A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

for Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)

Sites in Milwaukee +8 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: All ages

Code: NCT05788536·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Cancer

Sites in Milwaukee +8 more locations

Sponsor: Daiichi Sankyo

Sex: Male·Age: 18+

Code: NCT07244341·Phase 1·Recruiting·Listed Nov 2025

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Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

for Prostate Cancer

Sites in Milwaukee +6 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT06613100·Phase 1·Recruiting·Listed Sep 2024

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Asciminib Roll-over Study

for Chronic Myelogenous Leukemia

Sites in Milwaukee +4 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 7 - 100

Code: NCT04877522·Phase 4·Recruiting·Listed May 2021

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ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

for Acute Myelogenous Leukemia

Sites in Milwaukee +5 more locations

Sponsor: Beijing InnoCare Pharma Tech Co., Ltd.

Sex: All·Age: 18+

Code: NCT06656494·Phase 1·Recruiting·Listed Oct 2024

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REMASTer: REcurrent Brain Metastases After SRS Trial

for Brain Metastases

Sites in Milwaukee +7 more locations

Sponsor: Monteris Medical

Sex: All·Age: 18+

Code: NCT05124912·Recruiting·Listed Nov 2021

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Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

for Arthritis

Sites in Milwaukee +5 more locations

Sponsor: Aptis Medical

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT05796908·Recruiting·Listed Apr 2023

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SPI-1005 in Adults Receiving Cochlear Implant

for Hearing Loss

Sites in Milwaukee +5 more locations

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18+

Code: NCT06340633·Phase 2·Recruiting·Listed Apr 2024

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Combination of TATE and PD-1 Inhibitor in Liver Cancer

for Hepatocellular Carcinoma

Sites in Milwaukee +2 more locations

Sponsor: Teclison Ltd.

Sex: All·Age: 18 - 80

Code: NCT03259867·Phase 2·Recruiting·Listed Aug 2017

Apply to this trial