Paid Clinical Trials in Minneapolis, MN

As of September 2026, 897 paid clinical trials are recruiting in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

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811 clinical trials

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Neuroplasticity in RBD

for REM Sleep Behavior Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT05471960·Recruiting·Listed Jul 2022

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Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma

Drug: Epcoritamab

Sites in Minneapolis +2 more locations

Sponsor: Yazeed Sawalha

Sex: All·Age: 18+

Code: NCT06536049·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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Listening Effort in Cochlear Implant Users

for Auditory Perception

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06516575·Recruiting·Listed Jul 2024

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A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for Acute Myeloid Leukemia Post Cytotoxic Therapy

Sites in Minneapolis +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT07012044·Phase 1·Recruiting·Listed Jun 2025

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A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide

for Prostate Cancer (Adenocarcinoma)

Sites in Minneapolis +7 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 18+

Code: NCT06844383·Phase 2·Recruiting·Listed Feb 2025

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Multicenter ALS Imaging Study

for Amyotrophic Lateral Sclerosis

Sites in Minneapolis +2 more locations

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06735014·Recruiting·Listed Dec 2024

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Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury

for Traumatic Brain Injury

Sites in Minneapolis +1 more location

Sponsor: University of New Mexico

Sex: All·Age: 18 - 59

Code: NCT05236010·Recruiting·Listed Feb 2022

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Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS)

for Stickler Syndrome Type 1

Sites in Minneapolis, Rochester +3 more locations

Sponsor: Helen Keller Eye Research Foundation

Sex: All·Age: All ages

Code: NCT07146516·Recruiting·Listed Aug 2025

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

Sites in Minneapolis, Saint Louis Park +379 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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Assessment of Usability and Satisfaction With a Take-home Device Presenting Sound and Body Stimulation for Back Pain

for Chronic Lower Back Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06619418·Recruiting·Listed Oct 2024

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Radial vs. State-Of-The-Art Femoral Access for Bleeding and Access Site Complication Reduction in Cardiac Catheterization (REBIRTH)

for Patient Satisfaction

Sites in Minneapolis +5 more locations

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 18+

Code: NCT04077762·Recruiting·Listed Sep 2019

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Progress Complication

for Coronary Artery Disease

1 location in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 18+

Code: NCT05100940·Recruiting·Listed Oct 2021

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Progress Bifurcation Global Registry

for Coronary Artery Disease

1 location in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 18+

Code: NCT05100992·Recruiting·Listed Oct 2021

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Brain Organization, Development, and Response to Intervention in Individual Neonates

for Development, Infant

Sites in Minneapolis +1 more location

Sponsor: Washington University School of Medicine

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05843396·Recruiting·Listed May 2023

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Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics

for Tourette Syndrome

Sites in Minneapolis +1 more location

Sponsor: University of Minnesota

Sex: All·Age: 10 - 17

Code: NCT06194305·Phase 2·Recruiting·Listed Jan 2024

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Endogenous Pain Inhibition Deficiency in Chronic TMD Pain

for Chronic Temporomandibular Disorders (TMD)

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 74·Accepts healthy volunteers

Code: NCT06617494·Recruiting·Listed Sep 2024

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Natural History and Structural Functional Relationships in Fabry Renal Disease Treatment Outcomes(Changes)in Fabry Renal Disease Study

for Fabry Disease

2 locations in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 1 - 75

Code: NCT01581424·Recruiting·Listed Apr 2012

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Cognition and Ultrasound

for Healthy Participants

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07220655·Recruiting·Listed Oct 2025

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HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL

for Follicular Lymphoma

Drug: Tafasitamab

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06792825·Phase 2·Recruiting·Listed Jan 2025

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Evaluation of the SCALED (SCaling AcceptabLE cDs)

for Traumatic Brain Injury

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05628207·Recruiting·Listed Nov 2022

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Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

for Castration Resistant Metastatic Prostate Cancer

Sites in Minneapolis +5 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male·Age: 18 - 90

Code: NCT04363164·Phase 2·Recruiting·Listed Apr 2020

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Minneapolis, Saint Louis Park +584 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting·Listed Oct 2018

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Stellate Ganglion Block

for Esophagectomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT06271707·Phase 4·Recruiting·Listed Feb 2024

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Comparison of Weekly Somatrogon to Daily Genotropin in Children Born Small for Gestational Age or With Idiopathic Short Stature.

for ISS

Sites in Minneapolis +11 more locations

Sponsor: Rabin Medical Center

Sex: All·Age: 3 - 11

Code: NCT07226089·Phase 3·Recruiting·Listed Nov 2025

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Minneapolis +35 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

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Optimization of a Behavioral Intervention to Increase Physical Activity in Older Adults Living With HIV

for Hiv

Sites in Minneapolis +1 more location

Sponsor: Butler Hospital

Sex: All·Age: 50+

Code: NCT05752500·Recruiting·Listed Mar 2023

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

Sites in Minneapolis +18 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting·Listed Aug 2021

Apply to this trial

Multisite Advancement of Research on Chronic Posttraumatic Headache

for Posttraumatic Headache

Sites in Minneapolis +5 more locations

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 70

Code: NCT05620719·Recruiting·Listed Nov 2022

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Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder

for Opioid Use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07158853·Phase 1·Recruiting·Listed Sep 2025

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Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for Ovarian Cancer

Sites in Minneapolis, Rochester +7 more locations

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18+

Code: NCT04606914·Phase 2·Recruiting·Listed Oct 2020

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SMART Therapist Training: A Hybrid Factorial-SMART Design

for Stress Disorders, Post-Traumatic

Sites in Minneapolis +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07010770·Recruiting·Listed Jun 2025

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Choline and Iron Deficiency

for Pediatric Iron Deficiency

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 5 Months - 7 Months

Code: NCT06527391·Phase 2, Phase 3·Recruiting·Listed Jul 2024

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Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

for CBD

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 70·Accepts healthy volunteers

Code: NCT07069478·Recruiting·Listed Jul 2025

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Minneapolis +15 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)

for Gaucher Disease, Type 3

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 80

Code: NCT05586243·Recruiting·Listed Oct 2022

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Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

for Spinal Fusion

Sites in Minneapolis +7 more locations

Sponsor: AO Foundation, AO Spine

Sex: All·Age: 45+

Code: NCT06368245·Recruiting·Listed Apr 2024

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A Pilot Study of Microbiota Transplant With Antibiotic Preconditioning and Fiber Supplementation in Pulmonary Arterial Hypertension (GUT RESTORE-PAH)

for Pulmonary Arterial Hypertension

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06481852·Phase 1·Recruiting·Listed Jul 2024

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Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

for Oral Leukoplakia

Sites in Minneapolis & Saint Paul

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05727761·Phase 2·Recruiting·Listed Feb 2023

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Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT07008638·Phase 1, Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

Childhood Cancer Survivor Study

for Cancer

Sites in Minneapolis +26 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

Apply to this trial