Paid Clinical Trials in Minneapolis, MN

As of July 2026, 906 paid clinical trials are recruiting in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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822 clinical trials

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

Sites in Minneapolis, Saint Cloud +48 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting·Listed May 2021

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

Sites in Minneapolis, Rochester +46 more locations

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting·Listed Feb 2021

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Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

for Acute Decompensated Heart Failure

Sites in Minneapolis +36 more locations

Sponsor: Reprieve Cardiovascular, Inc

Sex: All·Age: 22+

Code: NCT06898515·Phase 3·Recruiting·Listed Mar 2025

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US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

Sites in Minneapolis, Rochester +35 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting·Listed Jun 2023

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Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

for Prostate Cancer

Sites in Minneapolis, Rochester +28 more locations

Sponsor: Janux Therapeutics

Sex: Male·Age: 18 - 100

Code: NCT05519449·Phase 1·Recruiting·Listed Aug 2022

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CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

Sites in Minneapolis, Rochester +24 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting·Listed Nov 2024

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A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Drug: Vosoritide

Sites in Minneapolis +30 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06382155·Phase 2·Recruiting·Listed Apr 2024

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FORWARD CAD IDE Study

for Coronary Arterial Disease (CAD)

Sites in Minneapolis +26 more locations

Sponsor: Shockwave Medical, Inc.

Sex: All·Age: 18+

Code: NCT06662500·Recruiting·Listed Oct 2024

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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

Sites in Minneapolis +41 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting·Listed Nov 2019

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A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

for Atrial Fibrillation

Sites in Minneapolis +38 more locations

Sponsor: Biosense Webster, Inc.

Sex: All·Age: 18 - 80

Code: NCT06455098·Recruiting·Listed Jun 2024

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Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

for IgA Nephropathy

Sites in Minneapolis +36 more locations

Sponsor: Calliditas Therapeutics AB

Sex: All·Age: 18+

Code: NCT06712407·Phase 4·Recruiting·Listed Dec 2024

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EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

for COVID-19

Sites in Minneapolis +23 more locations

Sponsor: Pfizer

Sex: All·Age: 0 - 17

Code: NCT05261139·Phase 3·Recruiting·Listed Mar 2022

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TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

for Tricuspid Regurgitation

Sites in Minneapolis +35 more locations

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18+

Code: NCT06137807·Recruiting·Listed Nov 2023

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MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

for In-Stent Restenosis

Sites in Minneapolis, Coon Rapids +26 more locations

Sponsor: Concept Medical Inc.

Sex: All·Age: 18 - 110

Code: NCT05908331·Recruiting·Listed Jun 2023

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Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for Type 2 Diabetes Mellitus

Sites in Minneapolis +11 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 14 - 75

Code: NCT07579702·Recruiting·Listed May 2026

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AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

Sites in Minneapolis +14 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

Continuous Dual Aspiration Technique With Zoom System for Stroke

for Ischemic Stroke

Sites in Minneapolis +15 more locations

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07491952·Recruiting·Listed Mar 2026

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Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

for Phenylketonuria

Sites in Minneapolis +11 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 18 - 65

Code: NCT07477691·Phase 4·Recruiting·Listed Mar 2026

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Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

for Non-Arteritic Anterior Ischemic Optic Neuropathy

Sites in Minneapolis, Rochester +16 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 50 - 80

Code: NCT07453888·Phase 3·Recruiting·Listed Mar 2026

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A Study of TAK-505 in Adults With Solid Tumors

for Malignant Solid Tumors

Sites in Minneapolis +14 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07436728·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)

for Paroxysmal AF

Sites in Minneapolis, Rochester +22 more locations

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 80

Code: NCT07308847·Recruiting·Listed Dec 2025

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A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

for Advanced Biliary Tract Cancer

Sites in Minneapolis +17 more locations

Sponsor: J-Pharma Co., Ltd.

Sex: All·Age: 18+

Code: NCT07265674·Phase 3·Recruiting·Listed Dec 2025

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Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

for Ig-E Mediated Food Allergy

Drug: RPT904

Sites in Minneapolis +21 more locations

Sponsor: RAPT Therapeutics, Inc.

Sex: All·Age: 12 - 55

Code: NCT07220811·Phase 2·Recruiting·Listed Oct 2025

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A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

Sites in Minneapolis +16 more locations

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting·Listed Jan 2026

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A Gaucher Disease Gene Therapy Trial With FLT201

for Gaucher Disease Type 1

Sites in Minneapolis +15 more locations

Sponsor: Spur Therapeutics

Sex: All·Age: 18+

Code: NCT07223944·Phase 3·Recruiting·Listed Nov 2025

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Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)

for Fragile X Syndrome

Sites in Minneapolis +14 more locations

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: Male·Age: 13 - 45

Code: NCT07209462·Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

for Symptomatic Genetic Dilated Cardiomyopathy

Sites in Minneapolis, Rochester +21 more locations

Sponsor: Kardigan, Inc.

Sex: All·Age: 18+

Code: NCT07210723·Phase 2, Phase 3·Recruiting·Listed Oct 2025

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A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

for Cytomegalovirus Prophylaxis

Sites in Minneapolis, Rochester +16 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: Up to 17

Code: NCT07199465·Phase 1·Recruiting·Listed Sep 2025

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A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

for Familial Pulmonary Fibrosis

Drug: Nerandomilast

Sites in Minneapolis +12 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07201922·Phase 3·Recruiting·Listed Oct 2025

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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for Colorectal Cancer

Sites in Minneapolis, Rochester +20 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07023289·Phase 2·Recruiting·Listed Jun 2025

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Diagnosing Epilepsy To EffeCT Change

for Epilepsy

Sites in Minneapolis, Rochester +17 more locations

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110337·Recruiting·Listed Aug 2025

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A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

for Multiple Myeloma

Drug: Daratumumab

Sites in Minneapolis, Rochester +15 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07095452·Phase 2, Phase 3·Recruiting·Listed Jul 2025

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Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

for Macular Telangiectasia Type 2 (MacTel)

Sites in Minneapolis +22 more locations

Sponsor: Neurotech Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06971939·Phase 4·Recruiting·Listed May 2025

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The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study

for Chemotherapy Induced Peripheral Neuropathy (CIPN)

Sites in Minneapolis +15 more locations

Sponsor: Luminate Medical, Inc.

Sex: All·Age: 18+

Code: NCT07142304·Recruiting·Listed Aug 2025

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Study of ORIC-944 in Patients With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Minneapolis +19 more locations

Sponsor: ORIC Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT05413421·Phase 1·Recruiting·Listed Jun 2022

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Abbott Cephea Mitral Valve Disease Registry

for Mitral Regurgitation

Sites in Minneapolis +22 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07069673·Recruiting·Listed Jul 2025

Apply to this trial

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

for Obesity

Sites in Minneapolis, Saint Paul +49 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT06672549·Phase 3·Recruiting·Listed Nov 2024

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Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

for Advanced Solid Tumor

Sites in Minneapolis +10 more locations

Sponsor: Aulos Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05267626·Phase 1, Phase 2·Recruiting·Listed Mar 2022

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Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

for Non-small Cell Lung Cancer (NSCLC)

Sites in Minneapolis, Rochester +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06170788·Phase 3·Recruiting·Listed Dec 2023

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Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

for Metastatic Melanoma

Drug: Lifileucel

Sites in Minneapolis +17 more locations

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05727904·Phase 3·Recruiting·Listed Feb 2023

Apply to this trial