Paid Clinical Trials in Minnesota

Minnesota has 2,372 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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2,372 clinical trials

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CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

26 locations incl. Phoenix

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting

Apply to this trial

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

248 locations incl. Jonesboro

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting

Apply to this trial

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

for Hormone Receptor Positive HER-2 Negative Breast Cancer

35 locations incl. Birmingham

Sponsor: Puma Biotechnology, Inc.

Sex: All·Age: 18+

Code: NCT06369285·Phase 2·Recruiting

Apply to this trial

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

for Leukemia

53 locations incl. Goodyear

Sponsor: Daiichi Sankyo

Sex: All·Age: 18 - 70

Code: NCT06578247·Phase 3·Recruiting

Apply to this trial

HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML

for Myeloid Malignancy

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06594445·Phase 1·Recruiting

Apply to this trial

Allo HSCT for High Risk Hemoglobinopathies

for Graft Failure

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 55·Accepts healthy volunteers

Code: NCT06872333·Phase 2·Recruiting

Apply to this trial

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

6 locations incl. Los Angeles

Sponsor: Syntrix Biosystems, Inc.

Sex: Male·Age: 18+

Code: NCT06228053·Phase 2·Recruiting

Apply to this trial

Novel Post-Surgical Incision Management to Prevent Ostomy Complications

for Ostomy

1 location in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 18+

Code: NCT06524401·Recruiting

Apply to this trial

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

50 locations incl. Montgomery

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

74 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting

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An Adjuvant Study to Evaluate SMS001 (Paclitaxel) in Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung Cancer (NSCLC)

1 location in Rochester

Sponsor: ToLymph Inc.

Sex: All·Age: 18 - 80

Code: NCT06693336·Phase 2·Recruiting

Apply to this trial

Development of a Novel Evaluation Scale of Mental Body Representation (MBR) for Adults With Spinal Cord Injury

for Spinal Cord Injuries

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07029802·Recruiting

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Non-invasive Venous Air Plethysmography Assessment of Venous Hemodynamics in Patients Suspected Deep Venous Obstruction Used in Conjunction With Intermittent Pneumatic Compression.

for Deep Vein Thrombosis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06519435·Recruiting

Apply to this trial

LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)

for Acute Kidney Injury

1 location in Rochester

Sponsor: University of Alberta

Sex: All·Age: 18+

Code: NCT06446739·Recruiting

Apply to this trial

Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer

for Lung Non-Small Cell Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06660407·Phase 2·Recruiting

Apply to this trial

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

for Metastatic Castration-Resistant Prostate Cancer

5 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT06531499·Phase 1·Recruiting

Apply to this trial

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

for Developmental and Epileptic Encephalopathy

31 locations incl. Little Rock

Sponsor: Longboard Pharmaceuticals

Sex: All·Age: 2 - 65

Code: NCT06719141·Phase 3·Recruiting

Apply to this trial

Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

for Heart Failure

6 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT06517186·Recruiting

Apply to this trial

AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction

for Aortic Stenosis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 60+

Code: NCT06580158·Recruiting

Apply to this trial

Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial

for Advanced Fallopian Tube Carcinoma

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT06639074·Phase 2·Recruiting

Apply to this trial

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

for Metabolic Dysfunction Associated Steatohepatitis

Drug: Survodutide

125 locations incl. Peoria

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06632457·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

for Hereditary Hemorrhagic Telangiectasia

8 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06659640·Phase 1, Phase 2·Recruiting

Apply to this trial

Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma

for Asthma

Drug: Lunsekimig

54 locations incl. Saraland

Sponsor: Sanofi

Sex: All·Age: 18 - 80

Code: NCT06676319·Phase 2·Recruiting

Apply to this trial

Individualizing Corticosteroid Use in Pneumonia

for Pneumonia

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05334316·Phase 2·Recruiting

Apply to this trial

A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)

for Von Willebrand Disease (VWD)

11 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: Up to 17

Code: NCT05582993·Phase 3·Recruiting

Apply to this trial

A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction

for Breast Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07047872·Recruiting

Apply to this trial

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

for Systemic Sclerosis

15 locations incl. Orange

Sponsor: Nkarta, Inc.

Sex: All·Age: 18 - 75

Code: NCT06733935·Phase 1, Phase 2·Recruiting

Apply to this trial

Combining a Smartphone App With Medications to Manage Heavy Drinking

for Alcohol Use Disorder (AUD)

15 locations incl. Phoenix

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80

Code: NCT06303778·Recruiting

Apply to this trial

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

for Chronic Subdural Hematoma

31 locations incl. Phoenix

Sponsor: The University of Texas Medical Branch, Galveston

Sex: All·Age: 40 - 90

Code: NCT06347796·Recruiting

Apply to this trial

Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease

for Parkinson's Disease

1 location in Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06405334·Recruiting

Apply to this trial

Phase 1b Clinical Trial to Evaluate PEP and EUFLEXXA for Knee Osteoarthritis (KOA)

for Knee Osteoarthritis

1 location in Rochester

Sponsor: Rion Inc.

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06463132·Phase 1·Not Yet Recruiting

Fiber Product for Gas, Bloating, and Bowel Regularity

for Bloating

1 location in Edina

Sponsor: Bell Cinical Service

Sex: All·Age: 18 - 90

Code: NCT06642766·Not Yet Recruiting

A Study to Investigate the Safety and Efficacy of SAR446523 Injected Subcutaneously in Adult Participants With Relapsed/Refractory Myeloma

for Plasma Cell Myeloma Refractory

5 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06630806·Phase 1·Recruiting

Apply to this trial

A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer

12 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644768·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of Sex Differences in Neurocirculatory Control

for Obstructive Sleep Apnea

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 20 - 70

Code: NCT06261034·Recruiting

Apply to this trial

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

for Scleroderma, Diffuse

14 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06655896·Phase 2·Recruiting

Apply to this trial

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting

Apply to this trial

A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06481852·Phase 1·Recruiting

Apply to this trial

A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

for Advanced Breast Cancer

35 locations incl. Springdale

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06638307·Phase 1·Recruiting

Apply to this trial

A Study of Cerebral Perfusion With tDCS in Chronic Hypoperfusion

for Moyamoya Syndrome

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06477107·Enrolling By Invitation