Paid Clinical Trials in Minnesota

Minnesota has 2,372 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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2,372 clinical trials

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Social Support Counseling Intervention for Kidney Transplant Candidates

for Kidney Transplant

1 location in Minneapolis

Sponsor: Hennepin Healthcare Research Institute

Sex: All·Age: 18+

Code: NCT06147076·Recruiting

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Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer

for Localized Prostate Adenocarcinoma

5 locations incl. Albert Lea

Sponsor: Mayo Clinic

Sex: Male·Age: 18+

Code: NCT06325046·Recruiting

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Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement

for Total Shoulder Arthroplasty

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT06143306·Phase 4·Recruiting

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A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

for Breast Cancer

5 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06247995·Phase 1, Phase 2·Recruiting

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Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergames Telerehabilitation Study)

for At Risk for AD-dementia, With Subjective Cognitive Decline

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 65 - 99·Accepts healthy volunteers

Code: NCT06340659·Recruiting

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EFS of the DUO System for Tricuspid Regurgitation

for Tricuspid Regurgitation

12 locations incl. Phoenix

Sponsor: CroiValve Limited

Sex: All·Age: 18+

Code: NCT05913908·Recruiting

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A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

for Metastatic HER2-positive Breast Cancer

48 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06435429·Phase 3·Recruiting

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SuperSaturated Oxygen Comprehensive Observational Registry

for STEMI - ST Elevation Myocardial Infarction

25 locations incl. Fountain Valley

Sponsor: TherOx

Sex: All·Age: 18 - 80

Code: NCT06438315·Recruiting

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Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

for Biliary Tract Cancer

Drug: Rilvegostomig

48 locations incl. Scottsdale

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT06467357·Phase 3·Recruiting

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Melodi Matrix™ in Breast Reconstruction

for Breast Reconstruction

10 locations incl. Palo Alto

Sponsor: Melodi Health, Inc.

Sex: Female·Age: 22+

Code: NCT06027996·Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

266 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18 Minutes+

Code: NCT06031688·Phase 2·Recruiting

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A Study to Assess Growth in Children With Idiopathic Short Stature

for Idiopathic Short Stature

40 locations incl. Phoenix

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 16

Code: NCT06309979·Recruiting

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Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

12 locations incl. Oakland

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT06332534·Phase 3·Recruiting

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Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib

for Alopecia Areata

Drug: Ritlecitinib

25 locations incl. Montgomery

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT06531109·Recruiting

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A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for Untreated Follicular Lymphoma

Drug: Rituximab

51 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06549595·Phase 3·Recruiting

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Utility of Intermittent Cryo-Compression Versus Traditional Icing Following Arthroscopic Rotator Cuff Repair

for Rotator Cuff Injuries

1 location in Plymouth

Sponsor: Allina Health System

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT05095909·Recruiting

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Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)

for Tricuspid Regurgitation

9 locations incl. Thousand Oaks

Sponsor: Innoventric LTD

Sex: All·Age: 18 - 85

Code: NCT06212193·Recruiting

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End-Tidal Oxygen for Intubation in the Emergency Department

for Critical Illness

3 locations incl. Minneapolis

Sponsor: Sydney Local Health District

Sex: All·Age: 18+

Code: NCT06578468·Recruiting

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tDCS and Cognitive Training for Restrictive Eating Disorders

for Anorexia Nervosa

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT06624150·Phase 1·Recruiting

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VTP-1000 in Adults With Celiac Disease

for Celiac Disease

16 locations incl. Los Angeles

Sponsor: Barinthus Biotherapeutics

Sex: All·Age: 18 - 70

Code: NCT06310291·EARLY_Phase 1·Recruiting

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Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

for Advanced Breast Cancer

Drug: Camizestrant

54 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06380751·Phase 3·Recruiting

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Wisconsin Ginseng for Decreasing Cancer Related Fatigue

for Malignant Solid Neoplasm

15 locations incl. Albert Lea

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06395441·Phase 3·Recruiting

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Unlimited Transportation Passes for Unstable Housed People Living With HIV Trial

for HIV

1 location in Minneapolis

Sponsor: The Aliveness Project

Sex: All·Age: 18+

Code: NCT06483152·Not Yet Recruiting

Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume

for Heart Failure

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06195059·Recruiting

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Implementation of Innovative Treatment for Moral Injury Syndrome: A Hybrid Type 2 Study

for Moral Injury Syndrome

5 locations incl. Little Rock

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06230887·Enrolling By Invitation

Long-term Safety and Tolerability of BHV-7000

for Focal Epilepsy

115 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06443463·Phase 2·Enrolling By Invitation

Investigations of Reproductive Cancers in Women

for Uterine Cancer

16 locations incl. Birmingham

Sponsor: PinkDx, Inc.

Sex: Female·Age: 45 - 100

Code: NCT06527157·Recruiting

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Ostomy Simulation for Patient Education Prior to Urologic Bowel Diversion Surgeries

for Ostomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06583577·Recruiting

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Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

for Chronic Obstructive Pulmonary Disease

5 locations incl. Boise

Sponsor: Seattle Institute for Biomedical and Clinical Research

Sex: All·Age: 18+

Code: NCT06390345·Recruiting

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Ultrasound-Guided Core Needle Biopsy to Stage Urothelial Carcinoma of the Bladder (US UCB)

for Bladder Urothelial Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07029256·Recruiting

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PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

for ATP-Binding Cassette Subfamily C Member 6 Deficiency

5 locations incl. Chicago

Sponsor: Inozyme Pharma

Sex: All·Age: All ages

Code: NCT06302439·Recruiting

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Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

for Brain Concussion

2 locations incl. San Diego

Sponsor: United States Naval Medical Center, San Diego

Sex: All·Age: 18 - 60

Code: NCT06413173·Recruiting

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Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

for Depressive Disorder, Major

Drug: Seltorexant

84 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 74

Code: NCT06559306·Phase 3·Recruiting

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting

Apply to this trial

PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting

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Under-Resourced Adults With Chronic Pain eHealth Study

for Chronic Pain

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06688864·Recruiting

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Prescription of Letrozole for Uterine Myoma

for Leiomyoma, Uterine

5 locations incl. Los Angeles

Sponsor: University of California, San Francisco

Sex: Female·Age: 21 - 53·Accepts healthy volunteers

Code: NCT06143631·Phase 4·Recruiting

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TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

for Tricuspid Regurgitation

36 locations incl. Phoenix

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18+

Code: NCT06137807·Recruiting

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A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for Extensive Stage-small Cell Lung Cancer

Drug: Atezolizumab

26 locations incl. Birmingham

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06362252·Phase 1, Phase 2·Recruiting

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Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

for Advanced Lung Non-Small Cell Carcinoma

318 locations incl. Fayetteville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 70+

Code: NCT06096844·Phase 3·Recruiting

Apply to this trial