Paid Clinical Trials in Minnesota

Minnesota has 2,222 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,932 clinical trials

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

for Bone Cancer Metastatic

Sites in Rochester +6 more locations

Sponsor: Society of Interventional Oncology

Sex: All·Age: 21+

Code: NCT06859801·Recruiting·Listed Mar 2025

Apply to this trial

LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)

for Acute Kidney Injury

1 location in Rochester

Sponsor: University of Alberta

Sex: All·Age: 18+

Code: NCT06446739·Recruiting·Listed Jun 2024

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Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

for Adult Growth Hormone Deficiency

Sites in Minneapolis +14 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 21 - 55

Code: NCT04867317·Phase 3·Recruiting·Listed Apr 2021

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AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness

for Serious Illness

Sites in Rochester +1 more location

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07009210·Recruiting·Listed Jun 2025

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American Indian Smokefree Native RCT

for Smoking Cessation

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06544811·Recruiting·Listed Aug 2024

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Visual Remapping to Aid Reading With Field Loss

for Age-related Macular Degeneration

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT03848663·Recruiting·Listed Feb 2019

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Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning

for Malignant Solid Neoplasm

Sites in Rochester, Mankato +5 more locations

Sponsor: Mayo Clinic

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06200116·Recruiting·Listed Jan 2024

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SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

for Biochemically Recurrent Prostate Carcinoma

Sites in Rochester, Mankato +4 more locations

Sponsor: Mayo Clinic

Sex: Male·Age: 18+

Code: NCT06205316·Phase 3·Recruiting·Listed Jan 2024

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MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma

for Autologous Stem Cell Transplant

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06377540·Phase 2·Recruiting·Listed Apr 2024

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Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

for Hematologic Disorders

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 55

Code: NCT01666080·Recruiting·Listed Aug 2012

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Allo HSCT Using RIC and PTCy for Hematological Diseases

for Acute Myelogenous Leukemia

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 75

Code: NCT05805605·Phase 2·Recruiting·Listed Apr 2023

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

Sites in Minneapolis +79 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting·Listed Aug 2023

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Ultrasound-Guided Core Needle Biopsy to Stage Urothelial Carcinoma of the Bladder (US UCB)

for Bladder Urothelial Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07029256·Recruiting·Listed Jun 2025

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A Prospective, Randomized Comparison Of Drainage Techniques After One- Or Two-Level Open Posterior Lumbar Decompression Or Decompression And Fusion

for Complications, Postoperative

1 location in Minneapolis

Sponsor: Twin Cities Spine Center

Sex: All·Age: 18 - 70

Code: NCT06820736·Recruiting·Listed Feb 2025

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Longitudinal Study of the Porphyrias

for Acute Porphyrias

Sites in Minneapolis +14 more locations

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting·Listed Mar 2012

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Comparing the Safety and Efficacy of Apixaban and Rivaroxaban

for Atrial Fibrillation

Sites in Minneapolis +4 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 65+

Code: NCT06953726·Phase 4·Recruiting·Listed May 2025

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Localized Leiomyosarcoma Biomarker Protocol

for Leiomyosarcoma

Sites in Rochester +2 more locations

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: All ages

Code: NCT04925089·Recruiting·Listed Jun 2021

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CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

for Trauma

Sites in Minneapolis +14 more locations

Sponsor: Jason Sperry

Sex: All·Age: 18 - 90

Code: NCT05958342·Phase 2·Recruiting·Listed Jul 2023

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An Open-Label, Pilot Clinical Trial To Test The Safety And Feasibility Of A Suspension of Freeze-dried Microbiota In Patients Undergoing Colon Resection

for Recurrent Clostridioides Difficile Infection

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06692179·Phase 1·Recruiting·Listed Nov 2024

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Pathways Mediating Impaired Postural Control in Parkinson's Disease

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 45 - 80·Accepts healthy volunteers

Code: NCT06464029·Recruiting·Listed Jun 2024

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Intestinal Microbiota Transplantation in Patients Undergoing Colon Resection

for Recurrent Clostridioides Difficile Infection

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06370884·Phase 1·Recruiting·Listed Apr 2024

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Hairy Cell Leukemia Patient Data Registry

for Leukemia, Other

Sites in Rochester +4 more locations

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT02560883·Recruiting·Listed Sep 2015

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

Sites in Minneapolis +68 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting·Listed Jan 2023

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Minneapolis +86 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

for Peripheral T Cell Lymphoma

Sites in Rochester +1 more location

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06508463·Phase 1·Recruiting·Listed Jul 2024

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Minneapolis, Saint Paul +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

Breastmilk in Response to a Bout of Exercise

for Infant Development

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06892483·Recruiting·Listed Mar 2025

Apply to this trial

The Actuate-CBC Study

for Telemedicine

Sites in Saint Paul +3 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05917652·Recruiting·Listed Jun 2023

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Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

for Primary T-cell Immunodeficiency Disorders

Sites in Minneapolis +1 more location

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 - 75·Accepts healthy volunteers

Code: NCT02579967·Phase 2·Recruiting·Listed Oct 2015

Apply to this trial

Integrated Cancer Repository for Cancer Research

for Pancreatic Cancer

Sites in Duluth, Brainerd +40 more locations

Sponsor: University of Nebraska

Sex: All·Age: 19 - 110·Accepts healthy volunteers

Code: NCT02012699·Recruiting·Listed Dec 2013

Apply to this trial

ALS/MND Natural History Study Data Repository

for ALS

Sites in Minneapolis +13 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

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Evaluation of Microbiota Transplant Therapy in Patients With Alopecia Areata

for Alopecia Areata

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06747611·Phase 2·Recruiting·Listed Dec 2024

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Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple Myeloma

for Recurrent Multiple Myeloma

Drug: Daratumumab

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06785415·Phase 1, Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

for Pancreatic Carcinoma

Sites in Rochester +7 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06271291·Recruiting·Listed Feb 2024

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Rehabilitation Following Reverse Total Shoulder Arthroplasty

for Shoulder Osteoarthritis

1 location in Bloomington

Sponsor: HealthPartners Institute

Sex: All·Age: 55+

Code: NCT03804853·Recruiting·Listed Jan 2019

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Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study

for Ovarian Cancer

Sites in Rochester +8 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT05287451·Recruiting·Listed Mar 2022

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Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered, HPV-unrelated Head and Neck Squamous Cell Carcinoma Who Experienced Disease Progression on a PD-1/L1 Inhibitor

for HPV-unrelated Head and Neck Squamous Cell Carcinoma

Sites in Worthington +3 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT04966481·Phase 3·Recruiting·Listed Jul 2021

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Rochester, Minneapolis +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

Apply to this trial

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

for Acute Leukemia

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 60

Code: NCT03314974·Phase 2·Recruiting·Listed Oct 2017

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Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

for Childhood Astrocytoma

Sites in Minneapolis +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 22

Code: NCT06894979·Phase 1·Recruiting·Listed Mar 2025

Apply to this trial