Paid Clinical Trials in Minnesota

Minnesota has 2,222 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,932 clinical trials

Parenting in 2 Worlds Multisite Trial

for Parenting

Sites in Saint Paul +3 more locations

Sponsor: Arizona State University

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT06324318·Phase 2·Recruiting·Listed Mar 2024

Apply to this trial

Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD)

for Interstitial Lung Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03478826·Recruiting·Listed Mar 2018

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Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

for Heart Failure

Sites in Rochester +5 more locations

Sponsor: Northwestern University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT06517186·Recruiting·Listed Jul 2024

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Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

for Cannabis Use

1 location in Saint Louis Park

Sponsor: HealthPartners Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07227324·Recruiting·Listed Nov 2025

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An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors

for Malignant Brain Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06667726·Phase 2·Recruiting·Listed Oct 2024

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Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

for Preeclampsia

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18 - 50

Code: NCT06333652·Phase 2·Recruiting·Listed Mar 2024

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An Internet-based Program to Help Cancer Survivors Manage Pain

for Cancer

Sites in Minneapolis, Saint Paul +147 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04462302·Recruiting·Listed Jul 2020

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CAPITAL DOREMI 2: Inotrope Versus Placebo Therapy for Cardiogenic Shock

for Shock, Cardiogenic

1 location in Rochester

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18+

Code: NCT05267886·Phase 4·Recruiting·Listed Mar 2022

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Mayo AVC Registry and Biobank

for Arrhythmogenic Right Ventricular Cardiomyopathy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT03049254·Recruiting·Listed Feb 2017

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Registry of Patients Prescribed Anticoagulation

for Acute Deep Vein Thrombosis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03504007·Recruiting·Listed Apr 2018

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PRIME: PReservIng Memory in Epilepsy

for Mesial Temporal Lobe Epilepsy

Sites in Rochester +1 more location

Sponsor: Nitin Tandon

Sex: All·Age: 18 - 65

Code: NCT05608408·Recruiting·Listed Nov 2022

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Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling

for Chronic Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07103135·Phase 1·Recruiting·Listed Aug 2025

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Wisconsin Ginseng for Decreasing Cancer Related Fatigue

for Malignant Solid Neoplasm

Sites in Rochester, Duluth +12 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06395441·Phase 3·Recruiting·Listed May 2024

Apply to this trial

Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial

for Malignant Solid Neoplasm

Sites in Rochester +1 more location

Sponsor: Mayo Clinic

Sex: All·Age: 10 - 25

Code: NCT07089927·Recruiting·Listed Jul 2025

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Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

Sites in Minneapolis +31 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting·Listed Mar 2022

Apply to this trial

One vs. Two Stents for Gallbladder Disease

for Recurrent Cholecystitis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 95

Code: NCT07222527·Recruiting·Listed Oct 2025

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mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders

for Bipolar Disorder

1 location in Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06204705·Recruiting·Listed Jan 2024

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PROMIS and Mobility Evaluation in Sarcoma Patients

for Sarcoma

Sites in Rochester +1 more location

Sponsor: University of Calgary

Sex: All·Age: 18+

Code: NCT07227961·Recruiting·Listed Nov 2025

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Scoliosis Shared Decision Making

for Scoliosis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 13+

Code: NCT03107533·Recruiting·Listed Apr 2017

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Concomitant Renal and Urinary Bladder Allograft Transplantation

for Chronic Kidney Diseases

2 locations in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 1 - 60

Code: NCT04626167·EARLY_Phase 1·Recruiting·Listed Nov 2020

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Gii'Igoshimong: Sitting With Your First Family

for Substance Use

1 location in Duluth

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07075081·Phase 2·Recruiting·Listed Jul 2025

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Minneapolis +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

Apply to this trial

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for Advanced Colorectal Carcinoma

Sites in Minneapolis, Saint Paul +194 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06073431·Recruiting·Listed Oct 2023

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Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

for Indolent B-Cell Non-Hodgkin Lymphoma

Sites in Rochester, Mankato +5 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06386315·Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

Oropharynx (OPX) Biomarker Trial

for Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06356272·Recruiting·Listed Apr 2024

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Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy

for Grade 1 Meningioma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT04082520·Phase 2·Recruiting·Listed Sep 2019

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Cerebrospinal Fluid Biomarkers for Brain Tumors

for Central Nervous System Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: All ages

Code: NCT04692324·Recruiting·Listed Dec 2020

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ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade Glioma

for Glioblastoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05917145·Phase 1·Recruiting·Listed Jun 2023

Apply to this trial

Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes

for PreDiabetes

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 25 - 65·Accepts healthy volunteers

Code: NCT06424106·Recruiting·Listed May 2024

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Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

for Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer

Sites in Rochester +2 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06374459·Phase 1, Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

University of Minnesota Transplant Registry

for Transplant Recipient

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: All ages

Code: NCT01062581·Recruiting·Listed Feb 2010

Apply to this trial

Multi-speed Ergonomic Wheelchair

for Spinal Cord Diseases

1 location in Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05776030·Recruiting·Listed Mar 2023

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Microelectrode Recordings From the Vagus Nerve in Awake Humans

for Epilepsy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06016686·Phase 1·Recruiting·Listed Aug 2023

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Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma

for Clinical Stage I Esophageal Adenocarcinoma AJCC v8

Sites in Rochester +1 more location

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06078709·Phase 2·Recruiting·Listed Oct 2023

Apply to this trial

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

for Glioma

Sites in Rochester +1 more location

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07074756·Recruiting·Listed Jul 2025

Apply to this trial

Management of Dyssynergic Defecation

for Dyssynergic Defecation

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT07225803·Recruiting·Listed Nov 2025

Apply to this trial

A Study of Paramedic HF Management

for Heart Failure

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06874556·Recruiting·Listed Mar 2025

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Adipose Tissue Blood Flow in Aging Humans

for Healthy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06096532·Recruiting·Listed Oct 2023

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Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief

for Neck Pain Musculoskeletal

Sites in Rochester +3 more locations

Sponsor: Baylor University

Sex: All·Age: 18 - 70

Code: NCT06906107·Recruiting·Listed Apr 2025

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Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI

for Prostate Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06315595·Recruiting·Listed Mar 2024

Apply to this trial