Paid Clinical Trials in Minnesota

Minnesota has 2,367 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,367 clinical trials

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A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa

for Retinitis Pigmentosa

2 locations incl. Boston

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT06891885·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

for Smoking Cessation

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07487818·Phase 2, Phase 3·Not Yet Recruiting

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for Macular Degeneration

9 locations incl. Mountain View

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07496567·Phase 2, Phase 3·Recruiting

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Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

for Weight Regain

9 locations incl. Irvine

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07015424·Recruiting

Apply to this trial

A Study Of Milk Consumption In Metabolic Syndrome

for Metabolic Syndrome

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 70

Code: NCT07401888·Recruiting

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AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

15 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting

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Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

for Urinary Retention Postoperative

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 35+

Code: NCT07174349·Phase 4·Recruiting

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MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases

for AML

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 2 - 75

Code: NCT07493538·Phase 2·Recruiting

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A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for Solid Tumors

Drug: INCB161734

68 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07522073·Phase 3·Recruiting

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GTB-5550 in Advanced Solid Tumors

for Tri-specific Killer Engager

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT07541573·Phase 1·Recruiting

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A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

for Breast Cancer

Drug: Ribociclib

6 locations incl. Marshall

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07405801·Phase 2·Recruiting

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Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection of Endometrial Cancer

for Endometrial Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 45+·Accepts healthy volunteers

Code: NCT07527143·Not Yet Recruiting

Chronic Evaluation of Novel Pacemaker System

for Ventricular Pacing With Rate Response

1 location in Minneapolis

Sponsor: Calyan Technologies

Sex: All·Age: 18+

Code: NCT06056817·Not Yet Recruiting

INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery

for Heart Failure

7 locations incl. Tampa

Sponsor: Abiomed Inc.

Sex: All·Age: 18 - 80

Code: NCT06965504·Not Yet Recruiting

A Phase 1/2 Study of the Safety and Tolerability of MT-125 in GBM Patients

for Glioblastoma (GBM)

3 locations incl. Phoenix

Sponsor: Myosin Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07185880·Phase 1, Phase 2·Recruiting

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GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

for Glioblastoma, IDH-Wildtype

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07301268·Phase 2·Recruiting

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A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.

for Coronary Artery Disease (CAD)

1 location in Rochester

Sponsor: EBI Anti Sepsis BV

Sex: All·Age: 18+

Code: NCT07357675·Phase 3·Not Yet Recruiting

A Phase 2/3 Study on the Efficacy and Safety of Mangaciclanol for Contrast-Enhanced MRI of CNS or Body in Adult Patients

for Known or Highly Suspected Central Nervous System (CNS) Lesion

1 location in Rochester

Sponsor: GE Healthcare

Sex: All·Age: 18+

Code: NCT07472491·Phase 2, Phase 3·Recruiting

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Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention - UH3

for Chronic Pain

1 location in Minneapolis

Sponsor: Minneapolis Veterans Affairs Medical Center

Sex: All·Age: 18+

Code: NCT07541599·Recruiting

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An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis

for Colorectal Carcinoma

4 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06557733·Phase 2·Recruiting

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Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)

for Long QT Syndrome (LQTS) 2

6 locations incl. Scottsdale

Sponsor: Thryv Therapeutics, Inc.

Sex: All·Age: 15+

Code: NCT07277582·Phase 2, Phase 3·Recruiting

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The Safety and Efficacy of Direct SLT in Pseudoexfoliation Glaucoma

for Pseudoexfoliation Glaucoma

3 locations incl. Alexandria

Sponsor: Vance Thompson Vision

Sex: All·Age: All ages

Code: NCT07401290·Not Yet Recruiting

Personalized Antisense Oligonucleotide Therapy for A Single Patient With CHCHD10 ALS (nL18576)

for Amyotrophic Lateral Sclerosis

1 location in Rochester

Sponsor: n-Lorem Foundation

Sex: All·Age: 18+

Code: NCT07423494·Phase 1, Phase 2·Not Yet Recruiting

Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

for Phenylketonuria

12 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 18 - 65

Code: NCT07477691·Phase 4·Not Yet Recruiting

Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

for Lung Cancer

8 locations incl. Duarte

Sponsor: Vergent Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT07499674·Phase 3·Recruiting

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A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

for Cytomegalovirus Prophylaxis

17 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: Up to 17

Code: NCT07199465·Phase 1·Recruiting

Apply to this trial

Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and Effectiveness

for Pulmonary Embolism Acute

6 locations incl. Saint Cloud

Sponsor: Angiodynamics, Inc.

Sex: All·Age: 18+

Code: NCT07280247·Recruiting

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A Study of Methylprednisolone in People Having Liver Surgery

for Hepatectomy

19 locations incl. Chicago

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07507643·Phase 3·Recruiting

Apply to this trial

A Study to Assess the Effects of Zigakibart on IgA Nephropathy.

for Immunoglobulin A Nephropathy (IgAN)

3 locations incl. Denver

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07146906·Phase 2·Recruiting

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LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis (UC)

Drug: LY4268989

49 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07415044·Phase 2·Recruiting

Apply to this trial

Pilot Evaluation of the StarGuide Next Generation SPECT/CT System

for Nuclear Medicine

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07272161·Enrolling By Invitation

Transition to KPL-387 Monotherapy Dosing & Administration Study

for Recurrent Pericarditis

14 locations incl. Phoenix

Sponsor: Kiniksa Pharmaceuticals International, plc

Sex: All·Age: 18 - 80

Code: NCT07288216·Phase 2·Recruiting

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ABBV-383 for the Treatment of Relapsed Refractory Waldenström Macroglobulinemia

for Recurrent Waldenstrom Macroglobulinemia

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07420959·Phase 1, Phase 2·Not Yet Recruiting

A Long-Term Observational Study of Patients With Fucosidosis

for Fucosidosis

2 locations incl. Orange

Sponsor: JCR Pharmaceuticals Co., Ltd.

Sex: All·Age: All ages

Code: NCT07615400·Recruiting

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An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors

for Malignant Brain Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06667726·Phase 2·Recruiting

Apply to this trial

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

for Breast Neoplasms

39 locations incl. Birmingham

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07214532·Recruiting

Apply to this trial

A Screening Program to Improve the Early Detection of Sporadic Pancreatic Cancer in Individuals With a High-Risk of Developing Pancreatic Cancer

for Pancreatic Ductal Adenocarcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 50 - 85

Code: NCT07324096·Recruiting

Apply to this trial

A Study of Mirikizumab Solution (LY3074828) in Healthy Participants

for Healthy

5 locations incl. Daytona Beach

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07446101·Phase 1·Recruiting

Apply to this trial

Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients

for Anatomic Stage I Breast Cancer AJCC v8

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18 - 50

Code: NCT07460752·Phase 2·Not Yet Recruiting

Continuous Dual Aspiration Technique With Zoom System for Stroke

for Ischemic Stroke

13 locations incl. Huntsville

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07491952·Recruiting

Apply to this trial