Paid Clinical Trials in North Carolina

North Carolina has 2,944 paid clinical trials enrolling now across cities including Durham, Chapel Hill and Winston-Salem. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in North Carolina include Duke University Medical Center, UNC Health and Wake Forest Baptist, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

2,944 clinical trials

↓ Download CSV

CoMind Early Feasibility Study

for Intracranial Pressure

14 locations incl. Sacramento

Sponsor: CoMind Technologies Limited

Sex: All·Age: 18+

Code: NCT06368648·Recruiting

Apply to this trial

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

for B-cell Non-Hodgkin Lymphoma

23 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06526793·Phase 2·Recruiting

Apply to this trial

Pediatric and Caregiver Traumatic Stress Intervention (PACTS)

for Traumatic Injury

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 1 - 6

Code: NCT06366282·Recruiting

Apply to this trial

Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

for Traumatic Brain Injury

1 location in Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: Up to 18

Code: NCT06697808·Recruiting

Apply to this trial

A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

for Noonan Syndrome

Drug: Vosoritide

22 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06668805·Phase 2·Recruiting

Apply to this trial

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

for Eosinophilic Esophagitis (EoE)

54 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 1+

Code: NCT06693531·Recruiting

Apply to this trial

Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®

for Insomnia

1 location in Durham

Sponsor: Idorsia Pharmaceuticals Ltd.

Sex: Female·Age: 15 - 50

Code: NCT06498128·Recruiting

Apply to this trial

International CRDS Registry

for Calcium Release Deficiency Syndrome

4 locations incl. San Francisco

Sponsor: Population Health Research Institute

Sex: All·Age: All ages

Code: NCT06508164·Recruiting

Apply to this trial

Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

for Pain, Postoperative

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 3 - 17·Accepts healthy volunteers

Code: NCT06576830·Phase 4·Recruiting

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

61 locations incl. Avondale

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT06617325·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for Chronic Graft-Versus-Host Disease (cGVHD)

26 locations incl. Duarte

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06619561·Phase 2·Recruiting

Apply to this trial

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

for Ventricular Ejection Fraction

8 locations incl. Orange

Sponsor: Peerbridge Health, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06699056·Recruiting

Apply to this trial

Understanding and Enhancing Health-Related Social Needs (HRSN) Screening Among Community Oncology Practices

for Cancer

33 locations incl. Newark

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06412029·Enrolling By Invitation

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

26 locations incl. Phoenix

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting

Apply to this trial

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

for Hormone Receptor Positive HER-2 Negative Breast Cancer

35 locations incl. Birmingham

Sponsor: Puma Biotechnology, Inc.

Sex: All·Age: 18+

Code: NCT06369285·Phase 2·Recruiting

Apply to this trial

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

for Leukemia

53 locations incl. Goodyear

Sponsor: Daiichi Sankyo

Sex: All·Age: 18 - 70

Code: NCT06578247·Phase 3·Recruiting

Apply to this trial

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

6 locations incl. Los Angeles

Sponsor: Syntrix Biosystems, Inc.

Sex: Male·Age: 18+

Code: NCT06228053·Phase 2·Recruiting

Apply to this trial

A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

for Non-cystic Fibrosis Bronchiectasis

7 locations incl. Birmingham

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06603246·Phase 1·Recruiting

Apply to this trial

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

50 locations incl. Montgomery

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting

Apply to this trial

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

for Obesity

16 locations incl. Ventura

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT06672549·Phase 3·Recruiting

Apply to this trial

A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities

for Obesity

Drug: Orforglipron

14 locations incl. Ventura

Sponsor: Eli Lilly and Company

Sex: All·Age: 12 - 17

Code: NCT06672939·Phase 3·Recruiting

Apply to this trial

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

74 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting

Apply to this trial

To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

for Difficult to Control Hypertension

29 locations incl. Little Rock

Sponsor: E-Star BioTech, LLC

Sex: All·Age: 18 - 80

Code: NCT06343298·Phase 2·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

for Migraine

Drug: Rimegepant

27 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT06616194·Phase 3·Recruiting

Apply to this trial

A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

for Epilepsy, Temporal Lobe

17 locations incl. Little Rock

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06422923·Phase 1, Phase 2·Recruiting

Apply to this trial

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

for Diabetic Foot Ulcer (DFU)

9 locations incl. Fresno

Sponsor: Tides Medical

Sex: All·Age: 18+

Code: NCT06681428·Recruiting

Apply to this trial

Mobile Anger Reduction Intervention

for Posttraumatic Stress Disorder

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT06094933·Recruiting

Apply to this trial

Training for Urinary Leakage Improvement After Pregnancy

for Urinary Incontinence

7 locations incl. San Diego

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 18+

Code: NCT06411158·Recruiting

Apply to this trial

LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)

for Degenerative Disc Disease

2 locations incl. Fort Wayne

Sponsor: Locate Bio Pty Ltd

Sex: All·Age: 22 - 80

Code: NCT06462729·Phase 1, Phase 2·Recruiting

Apply to this trial

Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study

for Sepsis, Septic Shock

5 locations incl. Gainesville

Sponsor: Bluejay Diagnostics, Inc.

Sex: All·Age: 22+

Code: NCT06654895·Recruiting

Apply to this trial

Xeltis Hemodialysis Access Graft (aXess) US Study

for End Stage Renal Disease

7 locations incl. Phoenix

Sponsor: Xeltis

Sex: All·Age: 18+

Code: NCT06494631·Enrolling By Invitation

Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

for Heart Failure

6 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT06517186·Recruiting

Apply to this trial

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

for Metabolic Dysfunction Associated Steatohepatitis

Drug: Survodutide

125 locations incl. Peoria

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06632457·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

for Hereditary Hemorrhagic Telangiectasia

8 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06659640·Phase 1, Phase 2·Recruiting

Apply to this trial

Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma

for Asthma

Drug: Lunsekimig

54 locations incl. Saraland

Sponsor: Sanofi

Sex: All·Age: 18 - 80

Code: NCT06676319·Phase 2·Recruiting

Apply to this trial

Prospective Evaluation of Clinical and Radiographic Outcomes Following Total Talus Replacement (PROCLAIM)

for Avascular Necrosis of the Talus

1 location in Charlotte

Sponsor: Restor3D

Sex: All·Age: 22+

Code: NCT06311331·Enrolling By Invitation

Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

for Obstetrical Complications

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT06605118·Phase 3·Recruiting

Apply to this trial

Streamlined Resin Y90 Radiation Segmentectomy for Small HCC

for Hepatocellular Carcinoma (HCC)

1 location in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06618300·Enrolling By Invitation

MED-EL Remote Care Multi-Center Feasibility Study

for Hearing Loss, Sensorineural

3 locations incl. Iowa City

Sponsor: Med-El Corporation

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05973669·Enrolling By Invitation

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

for Breast Reconstruction

22 locations incl. Los Angeles

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06575192·Phase 3·Recruiting

Apply to this trial