Clinical Trials at Yale New Haven Hospital

As of June 2026, 66 paid clinical trials are recruiting at Yale New Haven Hospital in New Haven, Connecticut. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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66 clinical trials at Yale New Haven Hospital

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A Validation Study to Evaluate the Performance of Caption Health Lung Guidance and Interpretation

for Shortness of Breath

4 locations incl. New Haven

Sponsor: Caption Health, Inc.

Sex: All·Age: 18+

Code: NCT05992324·Recruiting

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Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients

for Seizures

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 19 - 85

Code: NCT05784805·Recruiting

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Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension

for Postpartum Hypertension

3 locations incl. New Haven

Sponsor: Yale University

Sex: Female·Age: 18+

Code: NCT05884190·Recruiting

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SHAPE Test for Preoperative Risk Stratification

for Perioperative/Postoperative Complications

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT05743673·Recruiting

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Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants

for Premature

7 locations incl. Los Angeles

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: Up to 36 Weeks

Code: NCT05380401·Recruiting

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BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

for Advanced Solid Tumor

9 locations incl. New Haven

Sponsor: SillaJen, Inc.

Sex: All·Age: 18+

Code: NCT05768932·Phase 1·Recruiting

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Preoperative Silicone Ointment and Wound Healing

for Wound Heal

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05461157·Enrolling By Invitation

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Daratumumab

67 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05552222·Phase 3·Recruiting

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Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

for Prostate Cancer

32 locations incl. Birmingham

Sponsor: Janux Therapeutics

Sex: Male·Age: 18 - 100

Code: NCT05519449·Phase 1·Recruiting

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

42 locations incl. Phoenix

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting

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Use of Psychologist-administered Cognitive Behavioral Therapy (CBT) or Self-administered CBT for the Treatment of Anxiety and/or Depression in Inflammatory Bowel Disease (IBD)

for Crohn Disease

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05377840·Recruiting

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Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

45 locations incl. Birmingham

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05338697·Recruiting

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The DRAGON 2 Trial

for Colorectal Cancer Liver Metastases (CRLM)

1 location in New Haven

Sponsor: Maastricht University

Sex: All·Age: 18+

Code: NCT05428735·Recruiting

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HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

for Hip Fractures

19 locations incl. Chandler

Sponsor: Population Health Research Institute

Sex: All·Age: 45+

Code: NCT04743765·Recruiting

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The Stimulation To Induce Mothers Study

for Oxytocin

3 locations incl. New Haven

Sponsor: Yale University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05079841·Phase 4·Recruiting

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A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

24 locations incl. Paradise Valley

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04951622·Phase 3·Recruiting

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Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

for NAFLD

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 12 - 18

Code: NCT04634643·Recruiting

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Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

for Symptomatic Hypertrophic Cardiomyopathy (HCM)

Drug: Aficamten

52 locations incl. Birmingham

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT04848506·Phase 2, Phase 3·Enrolling By Invitation

Rheumatology Patient Registry and Biorepository

for Rheumatic Diseases

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT04402086·Recruiting

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Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA

for Aortic Aneurysm, Thoracoabdominal

2 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 50 - 95

Code: NCT02989948·Recruiting

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Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon

for Appendicitis

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT04168866·Recruiting

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

25 locations incl. Duarte

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

for Mitral Valve Regurgitation

78 locations incl. Birmingham

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18+

Code: NCT03242642·Recruiting

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A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma

for HER2/Neu+ Uterine Serous Carcinoma

3 locations incl. Tucson

Sponsor: Yale University

Sex: Female·Age: 18 - 100

Code: NCT02491099·Phase 2·Recruiting

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

Apply to this trial