Clinical Trials at Yale University

As of September 2026, 229 paid clinical trials are recruiting at Yale University, located at 310 CEDAR ST, 416A LAUDER HALL, NEW HAVEN, CT 06510-3218, phone (203) 785-6843 in New Haven, Connecticut. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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229 clinical trials at Yale University

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Pre-Operative Window of ET to Inform RT Decisions (POWER II)

for Breast Cancer Female

Sites in New Haven +5 more locations

Sponsor: University of Virginia

Sex: Female·Age: 65+

Code: NCT06507618·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry

for HIV

Sites in New Haven +1 more location

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT07136363·Recruiting·Listed Aug 2025

Apply to this trial

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for Metastatic Malignant Neoplasm in the Liver

Sites in New Haven, Orange +378 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05040360·Phase 2·Recruiting·Listed Sep 2021

Apply to this trial

Hyperfractionated Dual Equivalent Fractionated Radiation Therapy

for Diffuse Large B-Cell Lymphoma

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06898905·Recruiting·Listed Mar 2025

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Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

for Acute Myeloid Leukemia

Sites in New Haven +18 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06484062·Phase 1·Recruiting·Listed Jul 2024

Apply to this trial

Investigation of Lymph Node Biology in Kidney Cancer

for Renal Cell Carcinoma (RCC)

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07038733·Recruiting·Listed Jun 2025

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AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

for Advanced Melanoma and Normal or Impaired

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07027488·Phase 1·Recruiting·Listed Jun 2025

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Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for Malignant Solid Neoplasm

Sites in New Haven, Trumbull +31 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642611·Phase 3·Recruiting·Listed Dec 2022

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Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma

for Locally Advanced Urothelial Carcinoma

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07048457·Phase 2·Recruiting·Listed Jul 2025

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Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder

for Alcohol Use Disorder

Drug: Apremilast

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07029529·Phase 2·Recruiting·Listed Jun 2025

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5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC

for Squamous Cell Carcinoma of Head and Neck

Drug: Nivolumab

1 location in New Haven

Sponsor: Barbara Burtness

Sex: All·Age: 18+

Code: NCT05317000·Phase 2·Recruiting·Listed Apr 2022

Apply to this trial

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in New Haven, Hartford +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

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Congenital Uterine Anomalies: Identifying Cancer Associations and Genetic and Environmental Factors to Improve Clinical Care

for Congenital Uterine Anomaly

1 location in New Haven

Sponsor: Yale University

Sex: Female·Age: 13+

Code: NCT04661072·Recruiting·Listed Dec 2020

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

Sites in New Haven +8 more locations

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting·Listed Jul 2022

Apply to this trial

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

for Tobacco Use

2 locations in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 65

Code: NCT06609369·Phase 2·Recruiting·Listed Sep 2024

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Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

for HIV

Sites in New Haven +1 more location

Sponsor: Yale University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05547048·Phase 4·Recruiting·Listed Sep 2022

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Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for Long COVID

Drug: Baricitinib

Sites in New Haven +16 more locations

Sponsor: Wes Ely

Sex: All·Age: 18+

Code: NCT06631287·Phase 3·Recruiting·Listed Oct 2024

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FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy

for Breast Cancer Early Stage Breast Cancer (Stage 1-3)

Sites in New Haven +1 more location

Sponsor: Yale University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06917313·Phase 2·Recruiting·Listed Apr 2025

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Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

Sites in New Haven, North Haven +114 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting·Listed Sep 2023

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Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

for Prostate Adenocarcinoma

Sites in New Haven, North Haven +130 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT05806515·Phase 2·Recruiting·Listed Apr 2023

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Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

for Wellness

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05810259·Recruiting·Listed Apr 2023

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Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy

for HER2 Negative Breast Cancer

Drug: Ribociclib

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06953882·Phase 2·Recruiting·Listed May 2025

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Saci Nivo Rela for TNBC

for Metastatic Triple-negative Breast Cancer

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06963905·Phase 1, Phase 2·Recruiting·Listed May 2025

Apply to this trial

Mechanisms of Diuretic Resistance in Heart Failure, Aim 1

for Heart Failure

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05323487·Phase 1·Recruiting·Listed Apr 2022

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Engaging T-cells to Eliminate MRD in Newly Diagnosed Myeloma Optimizing Response With Talquetmab and Teclistamab (ROTATE)

for Multiple Myeloma

Drug: Teclistamab

Sites in New Haven +1 more location

Sponsor: Noffar Bar

Sex: All·Age: 18+

Code: NCT06993675·Phase 2·Recruiting·Listed May 2025

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in New Haven +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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Exploring Water-free Sodium Storage

for Peritoneal Dialysis, Heart Failure

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06872645·Recruiting·Listed Mar 2025

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in New Haven, Danbury +52 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

for Depressive Disorder, Major

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 60

Code: NCT05915013·Phase 1·Recruiting·Listed Jun 2023

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A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus

for Pancreatic Cancer

Sites in New Haven & Norwalk

Sponsor: Nuvance Health

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT03937453·Recruiting·Listed May 2019

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

Sites in New Haven, West Haven +292 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting·Listed Sep 2018

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

Sites in New Haven +72 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting·Listed Apr 2024

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Kidney Precision Medicine Project

for Acute Kidney Failure

Sites in New Haven +12 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04334707·Recruiting·Listed Apr 2020

Apply to this trial

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

for Coronary Artery Disease

Sites in New Haven +4 more locations

Sponsor: Sunnybrook Health Sciences Centre

Sex: All·Age: 18+

Code: NCT05427370·Recruiting·Listed Jun 2022

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Transformative Research in Diabetic Nephropathy

for Diabetic Nephropathies

Sites in New Haven +12 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 100

Code: NCT02986984·Recruiting·Listed Dec 2016

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Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain

for Pain, Chronic

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 29

Code: NCT06847360·Recruiting·Listed Feb 2025

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Mechanisms of Diuretic Resistance in Heart Failure, Aim 3

for Heart Failure

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06209359·Phase 1·Recruiting·Listed Jan 2024

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Alcohol-ROC-Training

for Binge Drinking

Sites in New Haven +1 more location

Sponsor: Yale University

Sex: All·Age: 18 - 26

Code: NCT05491551·Recruiting·Listed Aug 2022

Apply to this trial

Left vs Left Randomized Clinical Trial

for Heart Failure

Sites in New Haven, Hartford +55 more locations

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting·Listed Dec 2022

Apply to this trial

Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction

for Smoking

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 21+

Code: NCT06077240·Recruiting·Listed Oct 2023

Apply to this trial