Clinical Trials at Yale University

As of July 2026, 247 paid clinical trials are recruiting at Yale University, located at 310 CEDAR ST, 416A LAUDER HALL, NEW HAVEN, CT 06510-3218, phone (203) 785-6843 in New Haven, Connecticut. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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247 clinical trials at Yale University

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Circulating Tumor DNA

for ER+ Breast Cancer

7 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06923527·Phase 2·Recruiting

Apply to this trial

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

for Acute Myeloid Leukemia

22 locations incl. New Haven

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06484062·Phase 1·Recruiting

Apply to this trial

Simulation Trial of Telemedical Support for Paramedics

for Emergencies

9 locations incl. Los Angeles

Sponsor: Boston Medical Center

Sex: All·Age: 21+

Code: NCT06441760·Recruiting

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Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

19 locations incl. Los Angeles

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

27 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting

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Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

Drug: Teclistamab

14 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06465316·Phase 1·Recruiting

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Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for Long COVID

Drug: Baricitinib

17 locations incl. Tucson

Sponsor: Wes Ely

Sex: All·Age: 18+

Code: NCT06631287·Phase 3·Recruiting

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Pre-Operative Window of ET to Inform RT Decisions (POWER II)

for Breast Cancer Female

6 locations incl. New Haven

Sponsor: University of Virginia

Sex: Female·Age: 65+

Code: NCT06507618·Phase 3·Recruiting

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Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

for Advanced Malignant Solid Neoplasm

23 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05691491·Phase 1, Phase 2·Recruiting

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

25 locations incl. Phoenix

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting

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A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial

for Acute Kidney Injury

9 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05805709·Recruiting

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Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, AXIOM Trial

for Advanced Alveolar Soft Part Sarcoma

Drug: Atezolizumab

13 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT05333458·Phase 2·Recruiting

Apply to this trial

Natural History of Wilson Disease

for Wilson Disease

4 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: All ages

Code: NCT03334292·Recruiting

Apply to this trial

Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

10 locations incl. Aurora

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting

Apply to this trial

Supporting Parents in Affirming Their Children's Experiences of Stigma

for Parent-Child Relations

3 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 15+

Code: NCT05919849·Phase 1·Recruiting

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

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A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus

for Pancreatic Cancer

2 locations incl. New Haven

Sponsor: Nuvance Health

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT03937453·Recruiting

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Kidney Precision Medicine Project

for Acute Kidney Failure

13 locations incl. Tucson

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04334707·Recruiting

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Type 1 Diabetes Extension Study

for Type 1 Diabetes Mellitus

12 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 8 - 35

Code: NCT02734277·Recruiting

Apply to this trial

Alcohol-ROC-Training

for Binge Drinking

2 locations incl. Berkeley

Sponsor: Yale University

Sex: All·Age: 18 - 26

Code: NCT05491551·Recruiting

Apply to this trial

Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst

for Cardiac Arrest

5 locations incl. San Francisco

Sponsor: Boston Medical Center

Sex: All·Age: 18 - 89

Code: NCT03261089·Recruiting

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Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

for End Stage Renal Disease

6 locations incl. San Diego

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03803423·Recruiting

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Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

Apply to this trial

Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping

for Moderate to Severe Asthma

3 locations incl. Scottsdale

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 75

Code: NCT06385236·Phase 4·Recruiting

Apply to this trial

Effect of the Thrive AI Health App on Lifestyle Behaviors and Quality of Life

for Diabetes Type 2

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT07376655·Recruiting

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RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry

for HIV

2 locations incl. New Haven

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT07136363·Recruiting

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Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder

for Alcohol Use Disorder

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07029529·Phase 2·Recruiting

Apply to this trial

CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs

for Head and Neck Squamous Cell Carcinoma

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07172256·Phase 2·Recruiting

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Stress and Congestive Heart Failure

for Congestive Heart Failure

2 locations incl. Hartford

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT04551560·Recruiting

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Investigation of Lymph Node Biology in Kidney Cancer

for Renal Cell Carcinoma (RCC)

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07038733·Recruiting

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Saci Nivo Rela for TNBC

for Metastatic Triple-negative Breast Cancer

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06963905·Phase 1, Phase 2·Recruiting

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Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain

for Pain, Chronic

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 29

Code: NCT06847360·Recruiting

Apply to this trial

Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma

for Locally Advanced Urothelial Carcinoma

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07048457·Phase 2·Recruiting

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FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy

for Breast Cancer Early Stage Breast Cancer (Stage 1-3)

2 locations incl. New Haven

Sponsor: Yale University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06917313·Phase 2·Recruiting

Apply to this trial

Iadademstat + SBRT With Atezo in ES-SCLC

for Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Drug: Iadademstat

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07113691·Phase 1·Recruiting

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Hyperfractionated Dual Equivalent Fractionated Radiation Therapy

for Diffuse Large B-Cell Lymphoma

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06898905·Recruiting

Apply to this trial

Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing

for Heart Failure

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07281014·Phase 4·Recruiting

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Exploring Water-free Sodium Storage

for Peritoneal Dialysis, Heart Failure

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06872645·Recruiting

Apply to this trial

Luspatercept + Darbepoetin in MDS

for MDS (Myelodysplastic Syndrome)

3 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07096297·Phase 2·Recruiting

Apply to this trial