Depression Clinical Trials in New York, NY

As of August 2026, 53 paid clinical trials are recruiting for Depression in New York, New York. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

Related specialties in New York

Behavioral health· 150 Mental health· 132 Psychiatry· 129

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54 clinical trials for Depression

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Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression

for Major Depressive Disorder

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 90

Code: NCT06559826·Phase 2·Recruiting·Listed Aug 2024

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Invasive Decoding and Stimulation of Altered Reward Computations in Depression Patients

for Major Depressive Disorder

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 80

Code: NCT05239780·Recruiting·Listed Feb 2022

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Neural Circuit Effects of Ketamine in Depression

for Major Depressive Disorder

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06213324·Phase 4·Recruiting·Listed Jan 2024

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Harlem Strong Mental Health Coalition

for Stress-related Problem

2 locations in New York

Sponsor: City University of New York, School of Public Health

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05833555·Recruiting·Listed Apr 2023

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Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder

for Major Depressive Disorder

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 21 - 80

Code: NCT06592833·Phase 2·Recruiting·Listed Sep 2024

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An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression

for Depression

1 location in New York

Sponsor: Singula Institute

Sex: All·Age: 18 - 65

Code: NCT05466851·Recruiting·Listed Jul 2022

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Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33

for Major Depressive Disorder

Sites in New York, Orangeburg +1 more location

Sponsor: NYU Langone Health

Sex: All·Age: 18 - 65

Code: NCT05573074·Recruiting·Listed Oct 2022

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Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2) in Major Depressive Disorder (MDD)

for Major Depressive Disorder

1 location in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18 - 65

Code: NCT05757791·Phase 2·Recruiting·Listed Mar 2023

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Pramipexole to Enhance Social Connections

for Anxiety Disorders

Sites in New York +1 more location

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 50

Code: NCT06269146·Phase 2·Recruiting·Listed Feb 2024

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Brief Interventions for Coping with Distress

for Distress, Emotional

1 location in New York

Sponsor: Teachers College, Columbia University

Sex: All·Age: 18 - 65

Code: NCT05779761·Recruiting·Listed Mar 2023

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Lay-Delivered Behavioral Activation in Senior Centers

for Depression

Sites in New York +17 more locations

Sponsor: University of Washington

Sex: All·Age: 60+

Code: NCT04621877·Recruiting·Listed Nov 2020

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Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

for Major Depressive Disorder (MDD)

Sites in New York, Staten Island +17 more locations

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06830044·Phase 3·Recruiting·Listed Feb 2025

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A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

for Major Depressive Disorder

Sites in New York, Brooklyn +38 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06223880·Phase 4·Recruiting·Listed Jan 2024

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