Paid Clinical Trials in Ohio

Ohio has 3,477 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,477 clinical trials

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A Multicenter, Randomized, Double-Masked, Placebo-Controlled Pilot Study to Evaluate the Efficacy and Safety of ZOC2017217 in Subjects With Age-Related Cataract

for Age Related Cataracts

21 locations incl. Scottsdale

Sponsor: Ocusun Ophthalmic Pharmaceutical (Guangzhou) Co., Ltd.

Sex: All·Age: 50+

Code: NCT07395986·Phase 2·Enrolling By Invitation

A Study of Brenipatide in Adult Participants With Schizophrenia

for Schizophrenia

Drug: Brenipatide

31 locations incl. Little Rock

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 55

Code: NCT07410507·Phase 2·Recruiting

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KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for Bladder Cancer

3 locations incl. San Francisco

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07232602·Phase 1, Phase 2·Recruiting

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A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

for Uncontrolled Gout

48 locations incl. Birmingham

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07388498·Phase 3·Recruiting

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A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

for Traumatic Brain Injury

13 locations incl. Sacramento

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07455136·Recruiting

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A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

29 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting

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Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics

for Periodontitis, Diabetes Mellitus Type 2

1 location in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 18+

Code: NCT07298057·EARLY_Phase 1·Recruiting

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Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia

for Tardive Dyskinesia

17 locations incl. Bryant

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 75

Code: NCT07365462·Phase 2·Recruiting

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Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

for Metastatic Ewing Sarcoma

17 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 1+

Code: NCT07194044·Phase 1·Recruiting

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A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

for Dystonia

37 locations incl. Birmingham

Sponsor: Vima Therapeutics

Sex: All·Age: 18 - 65

Code: NCT07304089·Phase 2·Recruiting

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Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study

for Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07215988·Recruiting

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A Superiority Trial of Radiofrequency Ablation for Low Back Pain

for Chronic Low Back Pain (CLBP)

3 locations incl. Atlanta

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07222462·Recruiting

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Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for Ventral Hernia

11 locations incl. Riverside

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07226791·Phase 2·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

for Bipolar I Disorder

Drug: Icalcaprant

31 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06696755·Phase 2·Recruiting

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Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

for Prosthetic-joint Infection

9 locations incl. Sarasota

Sponsor: Peptilogics

Sex: All·Age: 18 - 80

Code: NCT07214311·Phase 2, Phase 3·Recruiting

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A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer

for Relapsed/Refractory Small Cell Lung Cancer

Drug: Nivolumab

5 locations incl. Detroit

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07325136·Phase 1, Phase 2·Recruiting

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

77 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting

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GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

for Type 1 Diabetes Mellitus

34 locations incl. Little Rock

Sponsor: Medtronic MiniMed, Inc.

Sex: All·Age: 7 - 85

Code: NCT07228117·Recruiting

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Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia

for Agitation Associated With Alzheimer's Disease Dementia

9 locations incl. Murrieta

Sponsor: Exciva GmbH

Sex: All·Age: 55 - 90

Code: NCT07284472·Phase 2, Phase 3·Recruiting

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Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease

for Parkinson's Disease

1 location in Cleveland

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT06857851·Not Yet Recruiting

AAV2-hAADC for Parkinson's Disease (PDCS-01)

for Parkinson's Disease (PD)

1 location in Columbus

Sponsor: Krzysztof Bankiewicz

Sex: All·Age: 18 - 75

Code: NCT07267065·Phase 1·Not Yet Recruiting

Study to Enable New Diagnostics for Pulmonary Microbes in People With CF

for Cystic Fibrosis (CF)

9 locations incl. La Jolla

Sponsor: Chris Goss

Sex: All·Age: 16+

Code: NCT07312734·Not Yet Recruiting

Decitabine and Nivolumab in Participants With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

for Head and Neck Cancer

Drug: Nivolumab

1 location in Cleveland

Sponsor: Kyunghee Burkitt, DO, PhD

Sex: All·Age: 18+

Code: NCT07216833·Phase 1·Not Yet Recruiting

Replication and Evaluation of the RISE-APS Model In New Contexts

for Elder Abuse

4 locations incl. Reseda

Sponsor: RISE Collaborative

Sex: All·Age: 60+

Code: NCT07368257·Not Yet Recruiting

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease

for Metastatic Breast Cancer in the Liver

4 locations incl. Tampa

Sponsor: Delcath Systems Inc.

Sex: All·Age: 18+

Code: NCT06875128·Phase 2·Recruiting

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A Study to Investigate the Improvement of Photosensitivity in Terms of Skin Lesions Associated With CEP Following Administration of Oral ATL-001 (Ciclopirox Oral Solution) in Participants Aged >18 Years of Age With CEP

for Congenital Erythropoietic Porphyria (CEP)

1 location in Cleveland

Sponsor: Atlas Molecular Pharma

Sex: All·Age: 18+

Code: NCT07024316·Phase 1, Phase 2·Recruiting

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Oral 5 Strain Probiotic for GI Toxicity Mitigation During Pelvic Radiation

for Radiation Injuries

1 location in Cincinnati

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT07231588·EARLY_Phase 1·Recruiting

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Pistachio Intake and Nutrition-Related Outcomes in Individuals on GLP-1 Therapy

for Dietary Change

1 location in Clevland

Sponsor: Ian J. Neeland, MD

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07244445·Recruiting

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Healthy Eating for My Infant: A Community- Informed Infant Obesity Prevention Program Addressing the Impact of Maternal Mental Health on Eating and Feeding

for Obesity & Overweight

1 location in Cincinnati

Sponsor: University of Cincinnati

Sex: All·Age: 2 Months - 21 Months·Accepts healthy volunteers

Code: NCT07284108·Enrolling By Invitation

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

for Schizophrenia

Drug: KarXT

18 locations incl. Anaheim

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 13 - 17

Code: NCT07288567·Phase 3·Recruiting

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A Trial of TAK-861 for the Treatment of Narcolepsy With Cataplexy

for Narcolepsy Type 1 (NT1)

11 locations incl. Redwood City

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT07363720·Phase 3·Recruiting

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Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

for Hepatitis

Drug: Larsucosterol

48 locations incl. Birmingham

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 18+

Code: NCT07428538·Phase 3·Recruiting

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Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

for Glioblastoma

10 locations incl. Boston

Sponsor: Alpheus Medical, Inc.

Sex: All·Age: 18 - 80

Code: NCT07225621·Phase 2·Recruiting

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A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

for Eosinophilic Asthma

20 locations incl. Long Beach

Sponsor: Kymera Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07323654·Phase 2·Recruiting

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Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD) Trial

for Alcohol-associated Hepatitis

6 locations incl. Indianapolis

Sponsor: Samer Gawrieh

Sex: All·Age: 18 - 70

Code: NCT07060638·Phase 2·Recruiting

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A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

for Acute Myeloid Leukaemia (AML)

6 locations incl. Bethesda

Sponsor: Tempus AI

Sex: All·Age: 0+

Code: NCT07154823·Recruiting

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

212 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting

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A Study of Zasocitinib in Adults With Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Zasocitinib

15 locations incl. Scottsdale

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07244263·Phase 2·Recruiting

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A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD)

for Graves' Disease

Drug: IMVT-1402

89 locations incl. Phoenix

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07286006·Phase 2·Enrolling By Invitation

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

for Melanoma (Skin Cancer)

12 locations incl. Los Angeles

Sponsor: Aminex Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07287917·Phase 1, Phase 2·Recruiting

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