Paid Clinical Trials in Ohio

Ohio has 3,368 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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2,983 clinical trials

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

for Squamous Cell Carcinoma of Head and Neck

Drug: Amivantamab

Sites in Cleveland +13 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06385080·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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4D-710 in Adult Patients With Cystic Fibrosis

for Cystic Fibrosis Lung

Sites in Columbus, Cleveland +16 more locations

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 18+

Code: NCT05248230·Phase 2·Recruiting·Listed Feb 2022

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A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

for Lymphoma

Sites in Columbus, Cleveland +12 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT07015242·Phase 2·Recruiting·Listed Jun 2025

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Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

for AMI Cardiogenic Shock

Sites in Cincinnati +17 more locations

Sponsor: Abiomed Inc.

Sex: All·Age: 18+

Code: NCT06964685·Recruiting·Listed May 2025

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A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

for Head and Neck Squamous Cell Carcinoma (HNSCC)

Drug: Cemiplimab

Sites in Columbus +13 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06769698·Phase 2·Recruiting·Listed Jan 2025

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Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

for Central Line Associated Blood Stream Infections (CLABSI)

Sites in Cleveland +15 more locations

Sponsor: CorMedix

Sex: All·Age: 18+

Code: NCT06822426·Phase 3·Recruiting·Listed Feb 2025

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SLV-154 Treatment of Advanced Cancers

for Advanced Cancer

Sites in Cleveland +9 more locations

Sponsor: Solve Therapeutics

Sex: All·Age: 12+

Code: NCT06771219·Phase 1·Recruiting·Listed Jan 2025

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A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

for Systemic Lupus Erythematosus

Drug: Inebilizumab

Sites in Cleveland +11 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 75

Code: NCT06570798·Phase 2·Recruiting·Listed Aug 2024

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A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)

for PIK3CA-Related Overgrowth Spectrum (PROS)

Sites in Cleveland, Cincinnati +18 more locations

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 2+

Code: NCT06789913·Phase 2·Recruiting·Listed Jan 2025

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A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

for Relapsed or Refractory Multiple Myeloma (RRMM)

Sites in Cleveland +19 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06615479·Phase 3·Recruiting·Listed Sep 2024

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A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

for Multiple Sclerosis

Sites in Cleveland, Cincinnati +12 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18 - 60

Code: NCT06220201·Phase 1·Recruiting·Listed Jan 2024

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A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Cincinnati +16 more locations

Sponsor: Rein Therapeutics

Sex: All·Age: 40+

Code: NCT06968845·Phase 2·Recruiting·Listed May 2025

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A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

for Diffuse Large B-cell Lymphoma (DLBCL)

Drug: Odronextamab

Sites in Cleveland +17 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06091865·Phase 3·Recruiting·Listed Oct 2023

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Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.

for Juvenile Idiopathic Arthritis

Drug: Upadacitinib

Sites in Cincinnati +4 more locations

Sponsor: AbbVie

Sex: All·Age: 1 - 17

Code: NCT05609630·Phase 3·Recruiting·Listed Nov 2022

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Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

for Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Sites in Toledo, Sandusky +19 more locations

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06801834·Phase 3·Recruiting·Listed Jan 2025

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Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for Treatment Resistant Depression

Sites in Columbus, Cleveland +22 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 22 - 70

Code: NCT06423430·Recruiting·Listed May 2024

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A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

for Prostate Cancer

Sites in Cincinnati +11 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT07005154·Phase 2·Recruiting·Listed Jun 2025

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MYLUNG Consortium Part 3: Observational Study

for Carcinoma, Non-Small-Cell Lung

Sites in Cincinnati +9 more locations

Sponsor: US Oncology Research

Sex: All·Age: 18+

Code: NCT05885698·Recruiting·Listed Jun 2023

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Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

for Atrial Fibrillation (AF)

Sites in Columbus, Cleveland +16 more locations

Sponsor: Arga Medtech SA

Sex: All·Age: 18 - 80

Code: NCT06784466·Recruiting·Listed Jan 2025

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A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

for Chronic Migraine in Children

Sites in Cincinnati +9 more locations

Sponsor: H. Lundbeck A/S

Sex: All·Age: 12 - 17

Code: NCT04965675·Phase 3·Recruiting·Listed Jul 2021

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Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease

for Aortoiliac Occlusive Disease

Sites in Columbus +19 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 100

Code: NCT06872905·Recruiting·Listed Mar 2025

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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

for Heart Failure

Sites in Cleveland, Cincinnati +18 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 29 Days - 17

Code: NCT05714085·Phase 2, Phase 3·Recruiting·Listed Feb 2023

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A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

for Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations

Sites in Canton +14 more locations

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05967689·Phase 2·Recruiting·Listed Aug 2023

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

Sites in Hilliard +20 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting·Listed Jan 2025

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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for Solid Tumors With HRAS Alterations

Sites in Columbus +21 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06026410·Phase 1·Recruiting·Listed Sep 2023

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Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

Sites in Cleveland +11 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT06332534·Phase 3·Recruiting·Listed Mar 2024

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A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

for Follicular Lymphoma (FL)

Drug: Odronextamab

Sites in Cleveland +13 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06091254·Phase 3·Recruiting·Listed Oct 2023

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A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for Advanced Solid Tumors

Sites in Cleveland +8 more locations

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06760819·Phase 2·Recruiting·Listed Jan 2025

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A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Columbus +22 more locations

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting·Listed Aug 2024

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XTX301 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Columbus, Cleveland +8 more locations

Sponsor: Xilio Development, Inc.

Sex: All·Age: 18+

Code: NCT05684965·Phase 1, Phase 2·Recruiting·Listed Jan 2023

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A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)

for Duchenne Muscular Dystrophy

Sites in Columbus +11 more locations

Sponsor: Solid Biosciences Inc.

Sex: Male·Age: 0 - 17

Code: NCT06138639·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

for Breast Cancer, Metastatic

Sites in Canton +20 more locations

Sponsor: ALX Oncology Inc.

Sex: All·Age: 18+

Code: NCT07007559·Phase 2·Recruiting·Listed Jun 2025

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Lead-212 PSV359 Therapy for Patients With Solid Tumors

for Pancreatic Ductal Adenocarcinoma

Sites in Columbus +10 more locations

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06710756·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

for Thrombocytopenia, Neonatal Alloimmune

Drug: Nipocalimab

Sites in Cincinnati +11 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT06533098·Phase 3·Recruiting·Listed Aug 2024

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A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

for Anemia, Sickle Cell

Sites in Cleveland +17 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06481306·Phase 1, Phase 2·Recruiting·Listed Jul 2024

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

Sites in Cleveland, Cincinnati +20 more locations

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting·Listed Sep 2023

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Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

for Ovarian Cancer

Sites in Columbus +16 more locations

Sponsor: Xencor, Inc.

Sex: All·Age: 15+

Code: NCT06276491·Phase 1·Recruiting·Listed Feb 2024

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Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

for Advanced Non-squamous Non-small-cell Lung Cancer

Sites in Canton +14 more locations

Sponsor: Genelux Corporation

Sex: All·Age: 18+

Code: NCT06463665·Phase 2·Recruiting·Listed Jun 2024

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DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for Glioblastoma (GBM)

Sites in Columbus +16 more locations

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT06805305·Phase 2·Recruiting·Listed Feb 2025

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VTP-1000 in Adults With Celiac Disease

for Celiac Disease

Sites in Columbus +15 more locations

Sponsor: Barinthus Biotherapeutics

Sex: All·Age: 18 - 70

Code: NCT06310291·EARLY_Phase 1·Recruiting·Listed Mar 2024

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