Paid Clinical Trials in Ohio

Ohio has 3,477 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,477 clinical trials

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A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Drug: Nivolumab

34 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221149·Phase 2, Phase 3·Recruiting

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Growth and Tolerance of Plant-based Enteral Formulas in Children Ages 12-17 Months.

for Formula Dependent Children 1 to 2 Years of Age

1 location in Columbus

Sponsor: Kate Farms Inc

Sex: All·Age: 12 Months - 17 Months

Code: NCT07231705·Recruiting

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Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion

for Liver Transplant Disorder

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07315204·Recruiting

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POP SINGER Pilot Study

for Chronic Pain

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+

Code: NCT07450131·Recruiting

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MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial

for Adult Obesity

Drug: Semaglutide

15 locations incl. Birmingham

Sponsor: Eccogene

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07505303·Phase 2·Not Yet Recruiting

Sternal Plating High Risk

for Heart Diseases

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06660186·Recruiting

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18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) in Tuberculosis Patients

for Tuberculosis, Pulmonary

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 18+

Code: NCT07077213·Recruiting

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A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

40 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361510·Phase 3·Recruiting

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Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer

for Anal Carcinoma

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Female·Age: 50+

Code: NCT07407647·Phase 2·Recruiting

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Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

for Knee Cartilage Defects

17 locations incl. Birmingham

Sponsor: Medipost, Inc.

Sex: All·Age: 18 - 75

Code: NCT07339111·Phase 3·Recruiting

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Long-Term Follow-up Study of Cantharidin (YCANTH [VP-102/TO-208]) in Patients With Common Warts (Verruca Vulgaris)

for Common Warts (Verruca Vulgaris)

4 locations incl. Saint Augustine

Sponsor: Verrica Pharmaceuticals Inc.

Sex: All·Age: 2+

Code: NCT07457918·Phase 3·Recruiting

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A Phase 1/2 Study of TRI-611 in ALK-Positive NSCLC

for ALK-positive NSCLC

7 locations incl. Aurora

Sponsor: TRIANA Biomedicines, Inc.

Sex: All·Age: 18+

Code: NCT07491497·Phase 1, Phase 2·Recruiting

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Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study

for Hypertension

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: Female·Age: 18+

Code: NCT07363343·Recruiting

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MyCap Mobile Application for Tracking Time Burden of Treatment for Patients With Pancreatic Cancer

for Pancreatic Adenocarcinoma

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07619391·Recruiting

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Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

for Advanced Ovarian Carcinoma

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Female·Age: 18+

Code: NCT07144826·EARLY_Phase 1·Recruiting

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A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

9 locations incl. Mobile

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07218341·Phase 4·Recruiting

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Interrater Reliability and Feasibility of the Lasater Clinical Judgment Rubric for Use in Physical Therapy Simulation

for Physical Therapy Education

1 location in Youngstown

Sponsor: Youngstown State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07449026·Recruiting

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Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for Pancreatic Cancer

Drug: daraxonrasib

5 locations incl. Baltimore

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT07491445·Phase 3·Recruiting

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Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

52 locations incl. Tucson

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

for CRC (Colorectal Cancer)

Drug: Bevacizumab

80 locations incl. Chandler

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07284849·Phase 3·Recruiting

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A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

for Lupus Erythematosus, Systemic

Drug: Nipocalimab

29 locations incl. Beverly Hills

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 75

Code: NCT07438496·Phase 3·Recruiting

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Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day

for Astigmatism

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07303920·Recruiting

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A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

15 locations incl. Irvine

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting

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Randomized Controlled Trial of Two Mobile Health Strategies to Manage Postpartum Hypertension

for Hypertension, Pregnancy Induced

3 locations incl. New York

Sponsor: Jennifer Lewey, MD, MPH

Sex: Female·Age: 18+

Code: NCT07209254·Recruiting

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Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG

for Malignant Brain Tumors

2 locations incl. Cleveland

Sponsor: Tiffany Hodges

Sex: All·Age: 18+

Code: NCT07438860·Phase 1·Not Yet Recruiting

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

1 location in Cincinnati

Sponsor: Stichting Hemato-Oncologie voor Volwassenen Nederland

Sex: All·Age: 18+

Code: NCT07223814·Phase 3·Recruiting

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Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLAD

for Lung Transplant Failure and Rejection

3 locations incl. Boston

Sponsor: Brian Keller

Sex: All·Age: 7+

Code: NCT07434869·Not Yet Recruiting

The Improving Sleep in African American Couples Study (ISAAC)

for Obstructive Sleep Apnea (OSA)

2 locations incl. Cleveland

Sponsor: MetroHealth Medical Center

Sex: All·Age: 30+

Code: NCT07447284·Not Yet Recruiting

Evaluating Laser Otoscope for Middle Ear Effusion Detection

for Middle Ear Effusion

1 location in Cleveland

Sponsor: MSTATT LLC

Sex: All·Age: 6 Months - 18

Code: NCT07454512·Not Yet Recruiting

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

for Mitochondrial Diseases

3 locations incl. Boston

Sponsor: Khondrion BV

Sex: All·Age: 18+

Code: NCT06451757·Phase 3·Recruiting

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Treating Young Children With Attention Deficit Hyperactivity Disorder

for Attention-Deficit/Hyperactivity Disorder (ADHD)

5 locations incl. Palo Alto

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3 - 5

Code: NCT07300956·Phase 4·Not Yet Recruiting

Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors

for Hematopoietic Stem Cell Transplantation

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 5 - 18

Code: NCT07375290·Phase 1·Recruiting

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A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections

for Overactive Bladder

2 locations incl. Cincinnati

Sponsor: TriHealth Inc.

Sex: Female·Age: 18+

Code: NCT07387315·Phase 4·Not Yet Recruiting

Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation

for Heart Failure (HF)

2 locations incl. Cleveland

Sponsor: Oslo University Hospital

Sex: All·Age: 18+

Code: NCT07436299·Not Yet Recruiting

Soy Tomato Juice to Improve Outcomes in Pancreatitis

for Recurrent Acute Pancreatitis

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18 - 80

Code: NCT07447687·Phase 1, Phase 2·Recruiting

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Trial of Oligometastasis SBRT With Immediate, Simulation-Free Treatment Delivery (OLIGO-SWIFT)

for Oligometastasis

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07079098·Phase 1·Recruiting

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An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for Stomatitis

20 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07357597·Phase 4·Not Yet Recruiting

Virtual Patient Groups for Sarcoidosis Associated Fatigue

for Sarcoidosis

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07073963·Recruiting

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Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

for Advanced Hepatocellular Carcinoma

107 locations incl. Berkeley

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT07166406·Phase 3·Recruiting

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Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

for Schizophrenia

Drug: KarXT

45 locations incl. Bryant

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07379827·Recruiting

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