Paid Clinical Trials in Ohio

Ohio has 3,365 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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2,992 clinical trials

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Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

for Tricuspid Regurgitation

Sites in Columbus, Cincinnati +44 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04097145·Recruiting·Listed Sep 2019

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Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

for Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

Sites in Youngstown +26 more locations

Sponsor: Bayer

Sex: All·Age: All ages

Code: NCT04142437·Recruiting·Listed Oct 2019

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SELUTION 4 De Novo Small Vessel IDE Trial

for Coronary Artery Disease

Sites in Cleveland, Cincinnati +62 more locations

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05946629·Recruiting·Listed Jul 2023

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ELEVATE-HFpEF Clinical Study

for Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Columbus +25 more locations

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 40+

Code: NCT06678841·Recruiting·Listed Nov 2024

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Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for Crohn's Disease

Sites in Columbus, Cincinnati +54 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024

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Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer

Sites in Cleveland +35 more locations

Sponsor: Protara Therapeutics

Sex: All·Age: 18+

Code: NCT05951179·Phase 2·Recruiting·Listed Jul 2023

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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for Pulmonary Hypertension

Sites in Cleveland +36 more locations

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06911632·Recruiting·Listed Apr 2025

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A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

for Episodic Migraine

Drug: Atogepant

Sites in Cincinnati +27 more locations

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05711394·Phase 3·Recruiting·Listed Feb 2023

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

for Acute Respiratory Distress Syndrome (ARDS)

Sites in Cleveland, Toledo +38 more locations

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06703073·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Bevacizumab

Sites in Cleveland, Toledo +38 more locations

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Cohort B: paridiprubart

Sites in Cleveland, Toledo +38 more locations

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701669·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

for Acute Respiratory Distress Syndrome (ARDS)

Sites in Cleveland, Toledo +38 more locations

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701682·Phase 2·Recruiting·Listed Nov 2024

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A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: Upadacitinib

Sites in Fairborn, Canal Winchester +24 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 11

Code: NCT06461897·Phase 3·Recruiting·Listed Jun 2024

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Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

Sites in Cleveland +27 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting·Listed May 2022

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Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

for Irritability Associated With Autism Spectrum Disorder

Sites in Avon Lake +27 more locations

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 5 - 17

Code: NCT06706674·Phase 3·Recruiting·Listed Nov 2024

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A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

for Alzheimer Disease

Drug: KarXT

Sites in Blue Ash +45 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT06937229·Phase 3·Recruiting·Listed Apr 2025

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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

for Colitis, Ulcerative

Sites in Cleveland +17 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 2 - 17

Code: NCT05076175·Phase 2, Phase 3·Recruiting·Listed Oct 2021

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An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

for Colitis, Ulcerative

Sites in Cincinnati, Westlake +25 more locations

Sponsor: Pfizer

Sex: All·Age: 18 - 64

Code: NCT06398626·Recruiting·Listed May 2024

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Pompe Disease Registry Protocol

for Glycogen Storage Disease Type II

Sites in Columbus, Cleveland +72 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00231400·Recruiting·Listed Oct 2005

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A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

Drug: Nadofaragene Firadenovec

Sites in Columbus, Cincinnati +37 more locations

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06545955·Phase 3·Recruiting·Listed Aug 2024

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First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

Sites in Columbus, Cleveland +22 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

Sites in Columbus +49 more locations

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting·Listed Sep 2024

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Fabry Disease Registry & Pregnancy Sub-registry

for Fabry Disease

Sites in Columbus, Cleveland +72 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00196742·Recruiting·Listed Sep 2005

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Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

for Acute Kidney Injury

Sites in Columbus, Cleveland +30 more locations

Sponsor: SeaStar Medical

Sex: All·Age: 18+

Code: NCT05758077·Recruiting·Listed Mar 2023

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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

for Generalized Anxiety Disorder (GAD)

Sites in Columbus, Cincinnati +45 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06846320·Phase 2·Recruiting·Listed Feb 2025

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Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

for Ovarian Cancer

Drug: Bevacizumab

Sites in Centerville +31 more locations

Sponsor: Daiichi Sankyo

Sex: Female·Age: 18+

Code: NCT06819007·Phase 3·Recruiting·Listed Feb 2025

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Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

for Non-Small Cell Lung Cancer, NSCLC

Sites in Cleveland +27 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06162221·Phase 1, Phase 2·Recruiting·Listed Dec 2023

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ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

for Aortic Valve Insufficiency

Sites in Cleveland, Cincinnati +30 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT05172973·Recruiting·Listed Dec 2021

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DALY II USA/ MB-CART2019.1 for DLBCL

for Refractory Diffuse Large B Cell Lymphoma (DLBCL)

Sites in Columbus +27 more locations

Sponsor: Miltenyi Biomedicine GmbH

Sex: All·Age: 18+

Code: NCT04792489·Phase 2·Recruiting·Listed Mar 2021

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Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

Sites in Columbus, Cincinnati +31 more locations

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07085767·Phase 3·Recruiting·Listed Jul 2025

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A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for Carcinoma, Non-Small-Cell Lung

Sites in Cleveland +24 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05208762·Phase 1·Recruiting·Listed Jan 2022

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ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

for Aortic Regurgitation

Sites in Columbus, Cleveland +27 more locations

Sponsor: JenaValve Technology, Inc.

Sex: All·Age: All ages

Code: NCT06608823·Recruiting·Listed Sep 2024

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Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

for Prurigo Nodularis

Drug: Nemolizumab

Sites in Dayton +38 more locations

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT06988618·Recruiting·Listed May 2025

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A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

for Major Depressive Disorder (MDD)

Sites in Independence, North Canton +26 more locations

Sponsor: Seaport Therapeutics

Sex: All·Age: 18 - 65

Code: NCT07065240·Phase 2·Recruiting·Listed Jul 2025

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AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

for Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Cincinnati +23 more locations

Sponsor: Cytokinetics

Sex: All·Age: 40 - 85

Code: NCT06793371·Phase 2·Recruiting·Listed Jan 2025

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TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis With Cardiomyopathy

Drug: Nucresiran

Sites in Columbus, Cleveland +40 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07052903·Phase 3·Recruiting·Listed Jul 2025

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Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387

for Pericarditis

Sites in Cleveland, Cincinnati +25 more locations

Sponsor: Kiniksa Pharmaceuticals International, plc

Sex: All·Age: 18 - 80

Code: NCT07010159·Phase 2, Phase 3·Recruiting·Listed Jun 2025

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Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

for Lewy Body Dementia Psychosis

Sites in Columbus, Cleveland +26 more locations

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 55 - 84

Code: NCT07029581·Phase 2·Recruiting·Listed Jun 2025

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A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for NASH - Nonalcoholic Steatohepatitis

Drug: Efruxifermin

Sites in Akron, Westlake +156 more locations

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06528314·Phase 3·Recruiting·Listed Jul 2024

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Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

Sites in Columbus, Shaker Heights +84 more locations

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05980949·Phase 3·Recruiting·Listed Aug 2023

Apply to this trial