Paid Clinical Trials in Orlando, FL

As of August 2026, 699 paid clinical trials are recruiting in Orlando, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 12, 2026.

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644 clinical trials

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

Sites in Orlando, Tampa +110 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting·Listed Mar 2024

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A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for Recurrent Langerhans Cell Histiocytosis

Sites in Orlando, Tampa +102 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 180 Days - 22

Code: NCT05828069·Phase 2·Recruiting·Listed Apr 2023

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

Sites in Orlando, Tampa +115 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting·Listed Nov 2019

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A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

for Malignant Glioma

Drug: Selinexor

Sites in Orlando, Tampa +105 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 Months - 21

Code: NCT05099003·Phase 1, Phase 2·Recruiting·Listed Oct 2021

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

Sites in Orlando, St. Petersburg +153 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Orlando, St. Petersburg +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

Sites in Orlando, Tampa +93 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting·Listed Apr 2024

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Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Sites in Orlando, Jacksonville +26 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 25

Code: NCT07022678·Phase 3·Recruiting·Listed Jun 2025

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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

for Ulcerative Colitis

Sites in Orlando, Jacksonville +17 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05230173·Recruiting·Listed Feb 2022

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A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

Sites in Orlando, Tampa +73 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting·Listed Oct 2023

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TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

for Cystic Fibrosis (CF)

Sites in Orlando, Hollywood +10 more locations

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18 Months - 11

Code: NCT07048574·Recruiting·Listed Jul 2025

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

Sites in Orlando, Tampa +154 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021

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A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for Down Syndrome

Drug: Nivolumab

Sites in Orlando, Tampa +148 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 30

Code: NCT04546399·Phase 2·Recruiting·Listed Sep 2020

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Orlando, Altamonte Springs +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

for Cystic Fibrosis

Sites in Orlando, Jacksonville +33 more locations

Sponsor: Sonya Heltshe

Sex: All·Age: Up to 10

Code: NCT04509050·Recruiting·Listed Aug 2020

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Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

Sites in Orlando, Tampa +19 more locations

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

Sites in Orlando, Tampa +99 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting·Listed May 2022

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A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

for Cardiovascular Disorder

Sites in Orlando, Tampa +33 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 7+

Code: NCT05705531·Recruiting·Listed Jan 2023

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Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

for Infant, Extremely Premature

Sites in Orlando, St. Petersburg +41 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 - 1

Code: NCT05685745·Recruiting·Listed Jan 2023

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Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

for Neuroblastoma

Sites in Orlando, Gainesville +17 more locations

Sponsor: Giselle Sholler

Sex: All·Age: 12 Months - 21

Code: NCT05489887·Phase 2·Recruiting·Listed Aug 2022

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Open-label Single-arm Study to Assess the Efficacy of Mirikizumab in Patients With Inflammatory Strictures Due to CD

for Crohn Disease

1 location in Orlando

Sponsor: Alimentiv Inc.

Sex: All·Age: 18+

Code: NCT06997965·Phase 4·Recruiting·Listed May 2025

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

Sites in Orlando, Tampa +39 more locations

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting·Listed Feb 2022

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Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

for Endometrial Cancer

Sites in Orlando, Miami +10 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT04291612·Recruiting·Listed Mar 2020

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Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for Atypical Teratoid/Rhabdoid Tumor

Sites in Orlando, Tampa +10 more locations

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 26

Code: NCT06465199·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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An International Observational Study of Adults With Acute Infection

for Infectious Disease

Sites in Orlando +19 more locations

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07069400·Recruiting·Listed Jul 2025

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Transdisciplinary Care for Young Adults With Type 1 Diabetes

for Type 1 Diabetes

Sites in Orlando +1 more location

Sponsor: Nemours Children's Clinic

Sex: All·Age: 17+

Code: NCT06172166·Recruiting·Listed Dec 2023

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A Pilot Study of RISE for Nurse Managers Retreat

for Burnout

1 location in Orlando

Sponsor: AdventHealth

Sex: All·Age: 18+

Code: NCT07298018·Recruiting·Listed Dec 2025

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Breaking Disparities in Access to Advanced Diabetes Technologies in Children With Type 1 Diabetes

for Diabetes Mellitus, Type 1

Sites in Orlando & Jacksonville

Sponsor: Nemours Children's Clinic

Sex: All·Age: 6 - 17

Code: NCT05849753·Recruiting·Listed May 2023

Apply to this trial

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for Lymphoblastic Leukemia

Sites in Orlando +16 more locations

Sponsor: Tanja Andrea Gruber

Sex: All·Age: Up to 1

Code: NCT05848687·Phase 1, Phase 2·Recruiting·Listed May 2023

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Orlando, Tampa +69 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

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Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia

for Hypoxic Ischemic Encephalopathy

Sites in Orlando & Gainesville

Sponsor: University of Florida

Sex: All·Age: Up to 6 Hours

Code: NCT02621944·EARLY_Phase 1·Recruiting·Listed Dec 2015

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Orlando, Tampa +43 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Orlando, Tampa +231 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial

for Extubation Failure

Sites in Orlando, Hollywood +14 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 0 Days - 9 Weeks

Code: NCT05446272·Recruiting·Listed Jul 2022

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

Sites in Orlando, Lakeland +28 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting·Listed Jan 2025

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Natural History of Wilson Disease

for Wilson Disease

Sites in Orlando +2 more locations

Sponsor: Yale University

Sex: All·Age: All ages

Code: NCT03334292·Recruiting·Listed Nov 2017

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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

Sites in Orlando, Tampa +169 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020

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High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

Sites in Orlando, Gainesville +15 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

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Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

for Muscle-Invasive Bladder Carcinoma

Sites in Orlando +2 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06529822·Phase 1·Recruiting·Listed Jul 2024

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Orlando, Tampa +209 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial