Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,654 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 9, 2026.

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3,654 clinical trials

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

Apply to this trial

Teen Brain Online II: Understanding How Social Media Affects the Teen Brain

for Depression

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13 - 17

Code: NCT06817993·Recruiting

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Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

for Leukemia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 25

Code: NCT06839456·Phase 1, Phase 2·Recruiting

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Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis

for Bacterial Conjunctivitis

38 locations incl. Little Rock

Sponsor: Baxis Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT06911424·Phase 3·Recruiting

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A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)

for Renal Cell Carcinoma, Clear Cell

Drug: Ipilimumab

6 locations incl. Boston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06708949·Phase 2·Recruiting

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A Study of Navenibart in Participants With Hereditary Angioedema

for Hereditary Angioedema (HAE)

Drug: navenibart

19 locations incl. Birmingham

Sponsor: Astria Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT06842823·Phase 3·Enrolling By Invitation

Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)

for Depressive Symptoms

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 13 - 17

Code: NCT07020572·Recruiting

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Antidepressant Adherence for Depressed Adults in Primary Care

for Depression

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 64

Code: NCT06496646·Recruiting

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Army-SPRING Army-Suicide Prevention Research

for Suicide

3 locations incl. Hartford

Sponsor: University of Pennsylvania

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06547008·Phase 1·Recruiting

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Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

for Ovarian Cancer

Drug: Bevacizumab

28 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: Female·Age: 18+

Code: NCT06819007·Phase 3·Recruiting

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A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

for Psoriasis

Drug: Tirzepatide

40 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06857942·Phase 4·Recruiting

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Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents

for Bipolar Disorder (BD)

4 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 12 - 21

Code: NCT06920940·Recruiting

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A Global Prospective Observational Study of Women With Fabry Disease and Their Infants During Pregnancy and Breastfeeding

for Fabry Disease

1 location in Philadelphia

Sponsor: Amicus Therapeutics

Sex: Female·Age: All ages

Code: NCT04252066·Recruiting

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Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

for Relapsed/Refractory KMT2A-r Acute Leukemia

11 locations incl. Los Angeles

Sponsor: PedAL BCU, LLC

Sex: All·Age: 0 - 21

Code: NCT06376162·Phase 1·Recruiting

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Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

for Ventricular Tachycardia (VT)

6 locations incl. Boston

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 85

Code: NCT06703489·Recruiting

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A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

5 locations incl. Celebration

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06803680·Phase 1·Recruiting

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Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study

for Vaping

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT06804109·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

for Chronic Obstructive Pulmonary Disease (COPD)

67 locations incl. Foley

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06883305·Phase 3·Recruiting

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An Open-Label Study of Azetukalner in Major Depressive Disorder

for Major Depressive Disorder

63 locations incl. Phoenix

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06922110·Phase 3·Enrolling By Invitation

Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines

for Healthy Adults

1 location in Philadelphia

Sponsor: Monell Chemical Senses Center

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06929455·Recruiting

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Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

31 locations incl. Tucson

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07032662·Phase 2·Recruiting

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Intralesional Injection of STS in Treatment of Calcinosis

for Systemic Sclerosis (SSc)

1 location in Pittsburgh

Sponsor: Robyn T. Domsic, MD, MPH

Sex: All·Age: 18+

Code: NCT06672822·Phase 2·Recruiting

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APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

for Overactive Bladder (OAB)

10 locations incl. Birmingham

Sponsor: Medstar Health Research Institute

Sex: Female·Age: 22+

Code: NCT06797245·Recruiting

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DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for Glioblastoma (GBM)

16 locations incl. Gilbert

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT06805305·Phase 2·Recruiting

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A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

92 locations incl. Dothan

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819878·Phase 3·Recruiting

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A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects

for Cataract

2 locations incl. Plymouth Meeting

Sponsor: Berkeley Eye Center

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT06922084·Phase 4·Recruiting

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Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for Clear Cell Renal Cell Carcinoma

414 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06661720·Phase 3·Recruiting

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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

194 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting

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Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults

for Cannabis Use

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT06743373·Recruiting

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A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

55 locations incl. Birmingham

Sponsor: Celgene

Sex: Male·Age: 18+

Code: NCT06764485·Phase 3·Recruiting

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Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression

for Depression, Postpartum

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+

Code: NCT06877104·Recruiting

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Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

for Lung Transplant

11 locations incl. Los Angeles

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12+

Code: NCT06476132·Phase 2·Recruiting

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Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

658 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting

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A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

for Relapsed or Refractory Multiple Myeloma (RRMM)

22 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06615479·Phase 3·Recruiting

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L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML

for Acute Myeloid Leukaemia (AML)

6 locations incl. Miami

Sponsor: Moleculin Biotech, Inc.

Sex: All·Age: 18 - 80

Code: NCT06788756·Phase 2, Phase 3·Recruiting

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A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

for Metastatic Colorectal Cancer

14 locations incl. Scottsdale

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06792695·Phase 2·Recruiting

Apply to this trial

Videos to Aid Decision Making for Fibroid Treatment

for Uterine Bleeding

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 55

Code: NCT07072364·Recruiting

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A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

for Menstrual Migraine

Drug: Rimegepant

32 locations incl. Phoenix

Sponsor: Pfizer

Sex: Female·Age: 18 - 45

Code: NCT06641466·Phase 3·Recruiting

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A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

for Urinary Bladder Neoplasms

Drug: Intismeran autogene

20 locations incl. Bakersfield

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06833073·Phase 2·Recruiting

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Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

for Suicide, Attempted

6 locations incl. St. Petersburg

Sponsor: Johns Hopkins University

Sex: All·Age: 12 - 24

Code: NCT06151158·Recruiting

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