Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,654 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 9, 2026.

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3,654 clinical trials

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

19 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting

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A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

for Lung Cancer

14 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06618287·Phase 1, Phase 2·Recruiting

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A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum

for Pyoderma Gangrenosum

19 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06624670·Phase 3·Recruiting

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Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

for Chronic Lymphocytic Leukaemia

3 locations incl. Charlotte

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06651970·Phase 4·Recruiting

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A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for KRAS G12C Mutation

11 locations incl. Phoenix

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06720987·Phase 1·Recruiting

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A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

for Anemia, Sickle Cell

4 locations incl. Wilmington

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 21

Code: NCT06290401·Recruiting

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Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

34 locations incl. Birmingham

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT06547489·Phase 2·Recruiting

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EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

for Glioblastoma

32 locations incl. Phoenix

Sponsor: NovoCure GmbH

Sex: All·Age: 18+

Code: NCT06556563·Phase 3·Recruiting

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Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for Extensive-stage Small-cell Lung Cancer

32 locations incl. Tucson

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712355·Phase 3·Recruiting

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Non-Invasive Preeclampsia Screening and Biobank

for Preeclampsia (PE)

21 locations incl. Glendale

Sponsor: Sequenom, Inc.

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06643741·Recruiting

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Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program

for Chronic Stress

5 locations incl. Harrisburg

Sponsor: Penn State University

Sex: All·Age: 11+·Accepts healthy volunteers

Code: NCT05789446·Recruiting

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Anticholinergic Deprescription in Schizophrenia

for Schizophrenia

1 location in Pittsburgh

Sponsor: Deepak K. Sarpal, M.D.

Sex: All·Age: 40 - 70·Accepts healthy volunteers

Code: NCT06562608·Phase 4·Recruiting

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Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

for Hereditary Angioedema (HAE)

12 locations incl. Birmingham

Sponsor: Pharvaris Netherlands B.V.

Sex: All·Age: 12+

Code: NCT06679881·Phase 3·Recruiting

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Point of Care Respiratory Pathogen Testing for Antibiotic Stewardship in Primary Care

for Upper Respiratory Infection

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06765135·Enrolling By Invitation

Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery

for Dysbiosis

1 location in Philadelphia

Sponsor: Acibadem Maslak Hospital

Sex: All·Age: 18 - 65

Code: NCT06791993·Phase 4·Not Yet Recruiting

Drinking in Young Adult Duos (DYAD) Study

for Alcohol Consumption

1 location in Pittsburgh

Sponsor: Carnegie Mellon University

Sex: All·Age: 21 - 30·Accepts healthy volunteers

Code: NCT06822257·Recruiting

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Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer

for Breast Cancer Surgery

4 locations incl. New Haven

Sponsor: Sir Mortimer B. Davis - Jewish General Hospital

Sex: Female·Age: 18 - 90

Code: NCT06888388·Recruiting

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StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

41 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting

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A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

for T-cell Acute Lymphoblastic Leukemia

13 locations incl. Duarte

Sponsor: Wugen, Inc.

Sex: All·Age: 1+

Code: NCT06514794·Phase 2·Recruiting

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BOOM-IBD2 Pivotal Clinical Trial

for Ulcerative Colitis

19 locations incl. Folsom

Sponsor: Boomerang Medical

Sex: All·Age: 18 - 85

Code: NCT06571669·Recruiting

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Evaluating the Durability of Closure for Venous Leg Ulcers

for Venous Leg

1 location in Monroeville

Sponsor: Kerecis Ltd.

Sex: All·Age: 18+

Code: NCT06697925·Recruiting

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

464 locations incl. Fairbanks

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting

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A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for Chronic Lymphocytic Leukaemia

13 locations incl. Boston

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06564038·Phase 1, Phase 2·Recruiting

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Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for Anaplastic Large Cell Lymphoma, ALK-Negative

158 locations incl. Birmingham

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18 - 75

Code: NCT06724237·Phase 3·Recruiting

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Tissue Repair Gel in Venous Leg Ulcers (US)

for Venous Leg Ulcer

33 locations incl. Tucson

Sponsor: TR Therapeutics

Sex: All·Age: 18+

Code: NCT06707090·Phase 3·Recruiting

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for Metastatic Head and Neck Squamous Cell Carcinoma

53 locations incl. Birmingham

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT06788990·Phase 2, Phase 3·Recruiting

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A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

for Sexual Dysfunction

3 locations incl. Coral Gables

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06541002·Recruiting

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A Long-Term Follow-Up Basket Study for Participants Treated With SynKIR Chimeric Antigen Receptor (CAR) T Cell Product

for Cancer

6 locations incl. Denver

Sponsor: Verismo Therapeutics

Sex: All·Age: 18+

Code: NCT06701201·Enrolling By Invitation

Evaluation of Uterine Fibroids by CEUS and SHAPE Pre and Post UAE

for Uterine Fibroid

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+

Code: NCT06705075·Phase 2·Recruiting

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A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia

for Narcolepsy Type 1

Drug: ALKS 2680

30 locations incl. Phoenix

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT06767683·Phase 2, Phase 3·Recruiting

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Flu Infection at UPHS

for Influenza Human

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06807840·Recruiting

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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension Due to Lung Diseases and Hypoxia

61 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT06388421·Recruiting

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Investigation of Filaggrin Gene Mutations Among Latinx Patients With Atopic Dermatitis

for Atopic Dermatitis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT06464133·Enrolling By Invitation

Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension

for Obesity

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 65

Code: NCT06482853·EARLY_Phase 1·Recruiting

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Healthy-donor Microbiome MTP-101-C in Steroid Relapse/Refractory Immune-related Cutaneous Adverse Events (irCAEs) and Immune-mediated Colitis (IMC)

for Immune-mediated Colitis (IMC)

1 location in Pittsburgh

Sponsor: Diwakar Davar

Sex: All·Age: 18+

Code: NCT06499896·Phase 2·Recruiting

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Massage Impact on Sleep in Pediatric Oncology

for Cancer

2 locations incl. Washington D.C.

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12 - 21

Code: NCT06892158·Recruiting

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A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

for Ulcerative Colitis

14 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT06100289·Phase 3·Recruiting

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Serranator POINT FORCE Registry

for Peripheral Artery Disease (PAD)

19 locations incl. Scottsdale

Sponsor: Cagent Vascular LLC

Sex: All·Age: 18+

Code: NCT06687590·Recruiting

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A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

for Geographic Atrophy

65 locations incl. Phoenix

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: All ages

Code: NCT06779773·Recruiting

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Examining Interactions Between PALS and Caregivers

for Amyotrophic Lateral Sclerosis (ALS)

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06819124·Recruiting

Apply to this trial