Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 11, 2026.

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3,655 clinical trials

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Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE

for Eosinophilic Esophagitis

25 locations incl. Scottsdale

Sponsor: Dr. Falk Pharma GmbH

Sex: All·Age: 18 - 75

Code: NCT06596252·Phase 3·Recruiting

Apply to this trial

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

for Acute Leukemia

26 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2+

Code: NCT04811560·Phase 1, Phase 2·Recruiting

Apply to this trial

An Internet-based Program to Help Cancer Survivors Manage Pain

for Cancer

149 locations incl. Fort Smith

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04462302·Recruiting

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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

for Pulmonary Arterial Hypertension

27 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07218029·Phase 3·Recruiting

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Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

for Locally Advanced (Inoperable) or Metastatic Breast Cancer

54 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT04862663·Phase 3·Recruiting

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Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for Metastatic Non Small Cell Lung Cancer

46 locations incl. Gilbert

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT04614103·Phase 2·Recruiting

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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

for Post Operative Surgical Site Infection

31 locations incl. Redwood City

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting

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KRT-232 and TKI Study in Chronic Myeloid Leukemia

for Chronic Myeloid Leukemia

5 locations incl. Birmingham

Sponsor: Kartos Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT04835584·Phase 1, Phase 2·Recruiting

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Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

for Symptomatic Hypertrophic Cardiomyopathy (HCM)

Drug: Aficamten

52 locations incl. Birmingham

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT04848506·Phase 2, Phase 3·Enrolling By Invitation

A Study of Intra-operative Imaging in Women With Ovarian Cancer

for Ovarian Cancer

9 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: All ages

Code: NCT04878094·Phase 3·Recruiting

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Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens

for Delayed Sleep Phase Syndrome

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13 - 15·Accepts healthy volunteers

Code: NCT04792697·Recruiting

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Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

17 locations incl. Los Angeles

Sponsor: Debiopharm International SA

Sex: All·Age: 12+

Code: NCT04855656·Phase 1·Recruiting

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A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.

for Spasticity

5 locations incl. Downey

Sponsor: Ipsen

Sex: All·Age: 18 - 70

Code: NCT04752774·Phase 1, Phase 2·Recruiting

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Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

for Acute Treatment of Migraine

Drug: Rimegepant

116 locations incl. Scottsdale

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT04743141·Phase 3·Recruiting

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Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for Recurrent Head and Neck Squamous Cell Carcinoma

178 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 79

Code: NCT04671667·Phase 2·Recruiting

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ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

for Acute Hepatic Porphyria

13 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 12+

Code: NCT04883905·Recruiting

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Childhood Cancer Predisposition Study (CCPS)

for Pediatric Cancer

6 locations incl. Atlanta

Sponsor: Emory University

Sex: All·Age: All ages

Code: NCT04511806·Recruiting

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

49 locations incl. Birmingham

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

for Low-grade Glioma

14 locations incl. San Francisco

Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All·Age: 6 Months - 25

Code: NCT04775485·Phase 2·Recruiting

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Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

for Propionic Acidemia

15 locations incl. Los Angeles

Sponsor: ModernaTX, Inc.

Sex: All·Age: All ages

Code: NCT04159103·Phase 1, Phase 2·Recruiting

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

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Auriculotherapy in the Treatment of Pre-Operative Anxiety

for Anxiety Preoperative

1 location in Pittsburgh

Sponsor: Jacques E. Chelly

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04836936·Recruiting

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Handoffs and Transitions in Critical Care - Understanding Scalability

for Patient Handoff

5 locations incl. Baltimore

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04571749·Enrolling By Invitation

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for High Grade Glioma

10 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04655404·EARLY_Phase 1·Recruiting

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Urban and Reservation Implementation of All Nations Breath of Life

for Smoking Cessation

1 location in Bethlehem

Sponsor: Lehigh University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04931810·Recruiting

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Ketone Ester Intervention in Alcohol Use Disorder

for Alcohol Drinking

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT04616781·Phase 2, Phase 3·Recruiting

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Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)

for Pancreatic Cancer

10 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 30 - 84

Code: NCT03460769·Recruiting

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COVID-19 Vaccines Safety Tracking (CoVaST)

for Adverse Reaction to Vaccine

1 location in Philadelphia

Sponsor: Masaryk University

Sex: All·Age: 18+

Code: NCT04834869·Recruiting

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

22 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting

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Abatacept for the Treatment of Giant Cell Arteritis

for Giant Cell Arteritis

5 locations incl. Rochester

Sponsor: University of Pennsylvania

Sex: All·Age: 50+

Code: NCT04474847·Phase 3·Recruiting

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Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

for Peripheral Vascular Diseases

52 locations incl. Jonesboro

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT04674969·Recruiting

Apply to this trial

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

for Medulloblastoma

23 locations incl. Little Rock

Sponsor: Giselle Sholler

Sex: All·Age: Up to 21

Code: NCT04696029·Phase 2·Recruiting

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A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

12 locations incl. Duarte

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT04786262·Phase 3·Recruiting

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Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

for Kidney Disease, End-Stage

16 locations incl. La Jolla

Sponsor: C. R. Bard

Sex: All·Age: 18+

Code: NCT04634916·Recruiting

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Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

for Motor Function

16 locations incl. Scottsdale

Sponsor: Guerbet

Sex: All·Age: 18 - 64

Code: NCT04373564·Phase 4·Recruiting

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ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study

for Transitional Cell Cancer of Renal Pelvis and Ureter

12 locations incl. Irvine

Sponsor: Steba Biotech S.A.

Sex: All·Age: 18+

Code: NCT04620239·Phase 3·Recruiting

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REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

for Lumbar Spinal Stenosis

10 locations incl. Santa Rosa

Sponsor: Pacific Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05504499·Recruiting

Apply to this trial

CTNNA1 Familial Expansion Study

for Cancer Gene Mutation

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05126290·Recruiting

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Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

for Advanced Solid Tumor Cancer

Drug: ABBV-CLS-484

15 locations incl. Tucson

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 18+

Code: NCT04777994·Phase 1·Recruiting

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

387 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting

Apply to this trial