Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 11, 2026.

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3,655 clinical trials

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A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

29 locations incl. Birmingham

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT04976322·Phase 3·Enrolling By Invitation

Biomechanical Footwear as a Non-invasive Alternative and Supplement to Total Knee Replacement

for Osteoarthritis, Knee

2 locations incl. Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 45 - 80

Code: NCT04732962·Recruiting

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GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

for Cystic Fibrosis

2 locations incl. Aurora

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04731272·Phase 2·Recruiting

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Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for Papillary Thyroid Cancer

8 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0+

Code: NCT05024929·Recruiting

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

149 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting

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Valved Graft PMCF Study

for Aortic Valve Disease

5 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT04754217·Recruiting

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CureDuchenne Link®: A Resource for Research

for Duchenne Muscular Dystrophy

10 locations incl. Little Rock

Sponsor: CureDuchenne

Sex: All·Age: 4 Weeks+

Code: NCT04972604·Recruiting

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Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs

for Liver Diseases

18 locations incl. Los Angeles

Sponsor: European Foundation for Study of Chronic Liver Failure

Sex: All·Age: 18 - 80

Code: NCT04613921·Recruiting

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Oral Nutritional Optimization in Total Joint Arthroplasty

for Osteoarthritis

2 locations incl. New York

Sponsor: NYU Langone Health

Sex: All·Age: 55+

Code: NCT04210284·Recruiting

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Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for Recurrent Ovarian High Grade Serous Adenocarcinoma

27 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT04633239·Phase 1·Recruiting

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Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

for Prostate Cancer

20 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04787744·Phase 2, Phase 3·Recruiting

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EyeConic: Qualification for Cone-Optogenetics

for Retinal Dystrophies

3 locations incl. San Francisco

Sponsor: Institute of Molecular and Clinical Ophthalmology Basel

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05294978·Recruiting

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Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

19 locations incl. Los Angeles

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting

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CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

for Cardiac Valve Disease

9 locations incl. Indianapolis

Sponsor: Corcym S.r.l

Sex: All·Age: All ages

Code: NCT05002543·Recruiting

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Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for Pulmonary Embolism

57 locations incl. Long Beach

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT04798261·Recruiting

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

812 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting

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A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

for Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer

12 locations incl. Duarte

Sponsor: Hoffmann-La Roche

Sex: Female·Age: 18+

Code: NCT04802759·Phase 1, Phase 2·Recruiting

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APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

for Pancreatic Acinar Cell Carcinoma

451 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04858334·Phase 2·Recruiting

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DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for Relapsed Diffuse Large B-cell Lymphoma

17 locations incl. Fountain Valley

Sponsor: ImmunoVaccine Technologies, Inc. (IMV Inc.)

Sex: All·Age: 18+

Code: NCT04920617·Phase 2·Recruiting

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IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

for Nontuberculous Mycobacterium Infection

10 locations incl. Birmingham

Sponsor: Chris Goss

Sex: All·Age: 18+

Code: NCT04294043·Phase 1·Recruiting

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Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

for Coronary Artery Disease

40 locations incl. Birmingham

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT04451044·Enrolling By Invitation

ATEMPT 2.0: Adjuvant T-DM1 vs TH

for Breast Cancer

53 locations incl. San Francisco

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04893109·Phase 2·Recruiting

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Long-Term Follow-Up of Patients Who Received Gene-Modified Cell Therapy

for Long-term Follow-up

1 location in Philadelphia

Sponsor: Sorrento Therapeutics, Inc.

Sex: All·Age: All ages

Code: NCT05472649·Enrolling By Invitation

Long Term Follow up of the LTOG Cohort

for Lung Transplant Failure and Rejection

10 locations incl. Birmingham

Sponsor: University of Pennsylvania

Sex: All·Age: 13+

Code: NCT04787822·Enrolling By Invitation

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for Prostate Cancer

24 locations incl. Tucson

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT04729114·Phase 1·Recruiting

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Persona Revision Knee System Outcomes

for Arthroplasty Complications

16 locations incl. Fayetteville

Sponsor: Zimmer Biomet

Sex: All·Age: 18+

Code: NCT04821154·Recruiting

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Device Global Registry for the IlluminOss Bone Stabilization System

for Traumatic Fracture

13 locations incl. Mobile

Sponsor: IlluminOss Medical, Inc.

Sex: All·Age: 50+

Code: NCT05206981·Recruiting

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Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

for Sickle Cell Disease

7 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 6 Months - 100

Code: NCT04657822·Phase 4·Recruiting

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Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

for Metastatic Lung Small Cell Carcinoma

223 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04804644·Phase 3·Recruiting

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Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

18 locations incl. Phoenix

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting

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Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer

for Breast Cancer

7 locations incl. Washington D.C.

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04841148·Phase 2·Recruiting

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Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for Ovarian Cancer

9 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18+

Code: NCT04606914·Phase 2·Recruiting

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A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

for Ulcerative Colitis

11 locations incl. San Francisco

Sponsor: Eli Lilly and Company

Sex: All·Age: 2 - 19

Code: NCT04844606·Phase 3·Recruiting

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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

for Tibial Fractures

13 locations incl. Indianapolis

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 80

Code: NCT07006675·Phase 3·Recruiting

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CrCest Study in Primary Mitochondrial Disease

for Mitochondrial Diseases

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 7 - 75

Code: NCT04734626·Enrolling By Invitation

DALY II USA/ MB-CART2019.1 for DLBCL

for Refractory Diffuse Large B Cell Lymphoma (DLBCL)

23 locations incl. Gilbert

Sponsor: Miltenyi Biomedicine GmbH

Sex: All·Age: 18+

Code: NCT04792489·Phase 2·Recruiting

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A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

for Plasmablastic Lymphoma

Drug: Daratumumab

8 locations incl. Miami

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT04139304·EARLY_Phase 1·Recruiting

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A Study of BGB-11417 in Participants With Myeloid Malignancies

for Acute Myeloid Leukemia

5 locations incl. Duarte

Sponsor: BeiGene

Sex: All·Age: 18+

Code: NCT04771130·Phase 1, Phase 2·Recruiting

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ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

for Aortic Aneurysm, Abdominal

9 locations incl. La Jolla

Sponsor: FCRE (Foundation for Cardiovascular Research and Education)

Sex: All·Age: 18+

Code: NCT04503395·Recruiting

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Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

for Metastatic Malignant Solid Neoplasm

7 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04585958·Phase 1·Recruiting

Apply to this trial