Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

for Open Midline Laparotomy

30 locations incl. Phoenix

Sponsor: C. R. Bard

Sex: All·Age: 18+

Code: NCT03911700·Recruiting

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Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

for Tricuspid Regurgitation

73 locations incl. Phoenix

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04097145·Recruiting

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Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

for Rectal Adenocarcinoma

10 locations incl. Hartford

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT04165772·Phase 2·Recruiting

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Medtronic Cardiac Surgery PMCF Registry

for Valve Disease, Heart

11 locations incl. Marietta

Sponsor: Medtronic Cardiac Surgery

Sex: All·Age: All ages

Code: NCT04073420·Recruiting

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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for Generalized Myasthenia Gravis

32 locations incl. Birmingham

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT04202341·Recruiting

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Abbott DBS Post-Market Study of Outcomes for Indications Over Time

for Movement Disorders

23 locations incl. Tucson

Sponsor: Abbott Medical Devices

Sex: All·Age: All ages

Code: NCT04071847·Recruiting

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Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

for Acute Leukemia

3 locations incl. Tampa

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 1 - 60

Code: NCT03970096·Phase 2·Recruiting

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University of Pittsburgh Brain Health Initiative

for Traumatic Brain Injury

1 location in Pittsburgh

Sponsor: David Okonkwo, MD, PhD

Sex: Male·Age: 29 - 59·Accepts healthy volunteers

Code: NCT04708613·Recruiting

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A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia

Drug: Revumenib

22 locations incl. Duarte

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 30 Days+

Code: NCT04065399·Phase 1, Phase 2·Recruiting

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HeartStart FRx Defibrillator Event Registry

for Sudden Cardiac Arrest

1 location in Monroeville

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: All ages

Code: NCT04250857·Recruiting

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Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors

for Advanced Solid Tumor

15 locations incl. Los Angeles

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT04145622·Phase 1, Phase 2·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab

for Solid Tumor, Adult

10 locations incl. Los Angeles

Sponsor: Linnaeus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT04130516·Phase 1, Phase 2·Recruiting

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Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)

for B-cell Acute Lymphoblastic Leukemia

14 locations incl. Los Angeles

Sponsor: Cellectis S.A.

Sex: All·Age: 15 - 50

Code: NCT04150497·Phase 1, Phase 2·Recruiting

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Von Willebrand Factor in Pregnancy (VIP) Study

for Von Willebrand Diseases

11 locations incl. Aurora

Sponsor: University of Washington

Sex: Female·Age: 18+

Code: NCT04146376·Recruiting

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Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study

for ADPKD

4 locations incl. Washington D.C.

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 18

Code: NCT04338048·Recruiting

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Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

for Congenital Disorders of Glycosylation

12 locations incl. San Diego

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: All ages

Code: NCT04199000·Recruiting

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Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients

for BK Polyomavirus

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 5 Weeks - 25

Code: NCT04293042·EARLY_Phase 1·Recruiting

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Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

for Spinal Cord Injuries

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT02592291·Recruiting

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Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

for Metastatic Castrate Resistant Prostate Cancer

18 locations incl. West Los Angeles

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04038502·Phase 2·Recruiting

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Parkinson's Disease and Movement Disorders Clinical Database

for Parkinson Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04997642·Recruiting

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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for Treatment Resistant Depression

98 locations incl. Birmingham

Sponsor: LivaNova

Sex: All·Age: 18+

Code: NCT03887715·Recruiting

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Li-Fraumeni Syndrome/TP53 Biobank

for Li-Fraumeni Syndrome

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04367246·Recruiting

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A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

for PAH

Drug: Ralinepag

48 locations incl. Phoenix

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT03683186·Phase 3·Enrolling By Invitation

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

for Colorectal Cancer

146 locations incl. Millville

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 60+

Code: NCT03998202·Recruiting

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A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

for Advanced Solid Tumor

Drug: Tulmimetostat

17 locations incl. Atlanta

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04104776·Phase 1, Phase 2·Recruiting

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

54 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting

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Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

for Smoldering Plasma Cell Myeloma

Drug: Daratumumab

741 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT03937635·Phase 3·Recruiting

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Dynamic Neural Mechanisms of Audiovisual Speech Perception

for Speech Perception

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 65

Code: NCT04290130·Enrolling By Invitation

Coflex PS3 Actual Conditions for Use Study

for Spinal Stenosis Lumbar

19 locations incl. Phoenix

Sponsor: Xtant Medical

Sex: All·Age: 18+

Code: NCT02555280·Recruiting

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Transforming Research and Clinical Knowledge in Geriatric Traumatic Brain Injury (TRACK-GERI)

for Traumatic Brain Injury

3 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07296783·Enrolling By Invitation

Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

for Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG

10 locations incl. Chicago

Sponsor: Theralase® Technologies Inc.

Sex: All·Age: 18+

Code: NCT03945162·Phase 2·Recruiting

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Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

for Acute Biphenotypic Leukemia

10 locations incl. Los Angeles

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 6 Months - 26·Accepts healthy volunteers

Code: NCT03779854·Phase 2·Recruiting

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Autonomic Control of the Circulation and VDR

for Venous Distension Reflex

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21 - 35·Accepts healthy volunteers

Code: NCT03513770·EARLY_Phase 1·Recruiting

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Cenobamate Open-Label Extension Study for YKP3089C025

for Primary Generalized Tonic Clonic Seizures in the Setting of Idiopathic Generalized Epilepsy

Drug: Cenobamate

16 locations incl. La Jolla

Sponsor: SK Life Science, Inc.

Sex: All·Age: 12+

Code: NCT03961568·Phase 3·Enrolling By Invitation

A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Drug: Cemiplimab

21 locations incl. Gilbert

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT03972657·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

for Myelodysplastic Syndromes (MDS)

12 locations incl. Los Angeles

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT04064060·Phase 3·Recruiting

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Pan Tumor Rollover Study

for Cancer

59 locations incl. Huntsville

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT03899155·Phase 2·Recruiting

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Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

for Haematological Malignancy

6 locations incl. Atlanta

Sponsor: CellCentric Ltd.

Sex: All·Age: 18+

Code: NCT04068597·Phase 1, Phase 2·Recruiting

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Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

for Colonic Neoplasms

11 locations incl. Los Angeles

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT00843375·Recruiting

Apply to this trial