Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0

for Cervical Deformity

16 locations incl. La Jolla

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04194996·Recruiting

Apply to this trial

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for Glioblastoma

42 locations incl. Birmingham

Sponsor: Global Coalition for Adaptive Research

Sex: All·Age: 18+

Code: NCT03970447·Phase 2, Phase 3·Recruiting

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GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

for Stroke

45 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 70

Code: NCT03821129·Recruiting

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Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors

for Solid Tumor

10 locations incl. Phoenix

Sponsor: Oxford BioTherapeutics Ltd

Sex: All·Age: 18+

Code: NCT04064359·Phase 1·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

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Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

for Metastatic Uveal Melanoma

12 locations incl. Los Angeles

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT03947385·Phase 1, Phase 2·Recruiting

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Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

for Clinical Stage I Esophageal Adenocarcinoma AJCC v8

95 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT03801876·Phase 3·Recruiting

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Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

for Colorectal Neoplasms

6 locations incl. Duarte

Sponsor: Surgimab

Sex: All·Age: 18+

Code: NCT03659448·Phase 3·Recruiting

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Phenotyping Genetic Risk for Type 2 Diabetes

for Diabetes Mellitus, Type 2

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 10 - 70·Accepts healthy volunteers

Code: NCT04024631·Recruiting

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The Impact of Glomerular Disorders on Bone Quality and Strength

for Glomerular Disease

2 locations incl. New York

Sponsor: Columbia University

Sex: All·Age: 5 - 55·Accepts healthy volunteers

Code: NCT04528446·Recruiting

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Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy

for Neovascular Age-related Macular Degeneration

9 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT03999801·Phase 2·Enrolling By Invitation

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

for Lower Respiratory Tract Infection

49 locations incl. Duarte

Sponsor: Ansun Biopharma, Inc.

Sex: All·Age: All ages

Code: NCT03808922·Phase 3·Recruiting

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ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

for Refractory Cancer

Drug: Nivolumab

13 locations incl. Stanford

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT03686124·Phase 1, Phase 2·Recruiting

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Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for Bladder Adenocarcinoma

Drug: Cabozantinib

578 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03866382·Phase 2·Recruiting

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Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

for B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

275 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03739814·Phase 2·Recruiting

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A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

for Secondary Hyperparathyroidism

10 locations incl. Los Angeles

Sponsor: Amgen

Sex: All·Age: 0 - 18

Code: NCT03633708·Phase 3·Recruiting

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The Johns Hopkins Heartburn Center Registry

for Gastroesophageal Reflux Disease

9 locations incl. Orange

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT03853772·Enrolling By Invitation

Oral Iron in Children With Chronic Kidney Disease

for Chronic Kidney Insufficiency

2 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 1 - 21

Code: NCT03991169·Phase 4·Recruiting

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Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy

for Pain, Postoperative

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT03737292·Phase 4·Recruiting

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[18F] F-GLN by PET/CT in Breast Cancer

for Breast Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT03863457·Phase 1·Recruiting

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Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

for Schizophrenia

1 location in Pittsburgh

Sponsor: Vishwajit Nimgaonkar, MD PhD

Sex: All·Age: 18 - 65

Code: NCT03794076·Phase 1, Phase 2·Recruiting

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Epilepsy Learning Healthcare System (ELHS)

for Epilepsy

13 locations incl. Phoenix

Sponsor: Epilepsy Foundation of America

Sex: All·Age: All ages

Code: NCT06265103·Recruiting

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Reduction of Adverse Drug Events and Readmissions

for Pharmacogenomic Testing for Medication Management

1 location in York

Sponsor: ClinLogic LLC

Sex: All·Age: 25+·Accepts healthy volunteers

Code: NCT02738047·Recruiting

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Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator

for Chronic Pain

30 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT03876054·Recruiting

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Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

for Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7

140 locations incl. Tucson

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT03493425·Phase 2·Recruiting

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Deep Brain Stimulation (DBS) Retrospective Outcomes Study

for Parkinson Disease

9 locations incl. Phoenix

Sponsor: Boston Scientific Corporation

Sex: All·Age: All ages

Code: NCT03664609·Recruiting

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Stress Hydrocortisone In Pediatric Septic Shock

for Septic Shock

18 locations incl. Tucson

Sponsor: Jerry Zimmerman

Sex: All·Age: 1 Month - 17

Code: NCT03401398·Phase 3·Recruiting

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Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

for Bone Pain

9 locations incl. Duarte

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT03858205·Recruiting

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Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

for Early Stage Non-Small Cell Lung Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT03546829·Phase 1·Recruiting

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CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT

for Acute Leukemia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 25

Code: NCT03810196·Recruiting

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Two Dose Levels of Privigen in Pediatric CIDP

for Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

9 locations incl. Phoenix

Sponsor: CSL Behring

Sex: All·Age: 2 - 17

Code: NCT03684018·Phase 4·Recruiting

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Metformin for Pulmonary Hypertension HFpEF

for Pulmonary Hypertension

2 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT03629340·Phase 2·Recruiting

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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

1229 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting

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The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

for Oncology

3 locations incl. Pittsburgh

Sponsor: UMC Utrecht

Sex: All·Age: 18+

Code: NCT04075305·Recruiting

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Studying Health Outcomes After Treatment in Patients With Retinoblastoma

for Retinoblastoma

10 locations incl. Chicago

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT03932786·Recruiting

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Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease

for Triple Negative Breast Cancer

12 locations incl. San Carlos

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT03808337·Phase 2·Recruiting

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Cardiac Sarcoidosis Randomized Trial

for Cardiac Sarcoidosis

9 locations incl. New Haven

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18+

Code: NCT03593759·Phase 3·Recruiting

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Whole Exome Sequencing and Whole Genome Sequencing for Nonimmune Fetal/Neonatal Hydrops

for Nonimmune Fetal Hydrops

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 16 - 55

Code: NCT03911531·Recruiting

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A Long-term Observational Study Evaluating Eteplirsen, Golodirsen, or Casimersen in Routine Clinical Practice

for Duchenne Muscular Dystrophy

20 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06606340·Enrolling By Invitation

Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates

for Schizophrenia

1 location in Philadelphia

Sponsor: Corporal Michael J. Crescenz VA Medical Center

Sex: All·Age: 18 - 75

Code: NCT03495024·Phase 4·Recruiting

Apply to this trial