Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

for Infant, Extremely Premature

37 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 - 1

Code: NCT05685745·Recruiting

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Caffeine Consumption in Glaucoma Patients and Healthy Subjects

for Glaucoma, Primary Open Angle

1 location in Philadelphia

Sponsor: Wills Eye

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT03675412·Recruiting

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Study of Individuals Affected With Hypoplasminogenemia

for Plasminogen Deficiency

13 locations incl. Birmingham

Sponsor: Indiana Hemophilia &Thrombosis Center, Inc.

Sex: All·Age: All ages

Code: NCT03797495·Recruiting

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Genetic and Epigenetic Basis of Chronic Wounds

for Chronic Wounds

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 100

Code: NCT03793062·Recruiting

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IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry

for Ventricular Arrhythmia

34 locations incl. Phoenix

Sponsor: University of California, Los Angeles

Sex: All·Age: All ages

Code: NCT04520347·Enrolling By Invitation

Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma

for Metastatic Melanoma

Drug: Nivolumab

3 locations incl. Lancaster

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT03646617·Phase 2·Recruiting

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

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Medtronic Terminate AF Study

for Persistent Atrial Fibrillation

15 locations incl. Palo Alto

Sponsor: Medtronic Cardiac Surgery

Sex: All·Age: 18+

Code: NCT03546374·Recruiting

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Brief Smartphone Treatment Study

for Generalized Anxiety Disorder

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18+

Code: NCT04846777·Recruiting

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Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

for Adenovirus

10 locations incl. Los Angeles

Sponsor: New York Medical College

Sex: All·Age: 1 Month - 79

Code: NCT03266627·Phase 2·Recruiting

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Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

for Cytomegalovirus Infections

9 locations incl. Los Angeles

Sponsor: New York Medical College

Sex: All·Age: 1 Month - 79

Code: NCT03266640·Phase 2·Recruiting

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Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

for Pulmonary Invasive Fungal Infections

32 locations incl. Little Rock

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 120 Days - 21

Code: NCT03827694·Recruiting

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A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee

for Chondral Defect

12 locations incl. Palo Alto

Sponsor: Vericel Corporation

Sex: All·Age: 10 - 17

Code: NCT03588975·Phase 3·Recruiting

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Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

for Smoking, Cigarette

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT03721822·Phase 1·Recruiting

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Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies

for Gastric Cancer

Drug: Cabozantinib

2 locations incl. Westwood

Sponsor: Anwaar Saeed

Sex: All·Age: 18+

Code: NCT03539822·Phase 1, Phase 2·Recruiting

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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

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Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

for Ewing Sarcoma

23 locations incl. Scottsdale

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 12 - 85

Code: NCT03715933·Phase 1·Recruiting

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Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

for Lactating Women on Select DOI

20 locations incl. La Jolla

Sponsor: Duke University

Sex: All·Age: All ages

Code: NCT03511118·Recruiting

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Molecular and Cellular Characterization of Skull Base Tumors

for Skull Base Neoplasm

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT03759717·Recruiting

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The Influence of Repairing the Sub-scapularis on Outcomes After Reverse Arthroplasty

for Severe Arthropathy With a Grossly Deficient Rotator Cuff

4 locations incl. St Louis

Sponsor: Encore Medical, L.P.

Sex: All·Age: 21+

Code: NCT03711175·Enrolling By Invitation

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

50 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

334 locations incl. Gilbert

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting

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WiTNNess - TNNT1 Myopathy Natural History Study

for TNNT1-associated Myopathy

1 location in Gordonville

Sponsor: Clinic for Special Children

Sex: All·Age: All ages

Code: NCT06374719·Recruiting

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Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

for Leukemia, Acute

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 60+

Code: NCT03680677·Recruiting

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Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

for Melanoma Stage IIIB

19 locations incl. Phoenix

Sponsor: Philogen S.p.A.

Sex: All·Age: 18+

Code: NCT03567889·Phase 3·Recruiting

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Extension Study for the Port Delivery System With Ranibizumab (Portal)

for Neovascular Age-Related Macular Degeneration

Drug: Ranibizumab

81 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50+

Code: NCT03683251·Phase 3·Recruiting

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

709 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting

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Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

for Opioid-use Disorder

1 location in Pittsburgh

Sponsor: Senthil Sadhasivam

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT03923374·Recruiting

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Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound

for Healthy

1 location in Pittsburgh

Sponsor: Carnegie Mellon University

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT03192436·Recruiting

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Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

for Ascending Aortic Aneurysm Enlargement

15 locations incl. San Francisco

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18 - 79

Code: NCT03536312·Recruiting

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Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for Solid Tumors

65 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT03486873·Phase 3·Recruiting

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Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

for Metastatic Urothelial Cancer

37 locations incl. Tucson

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT03547973·Phase 2·Recruiting

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Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

for Carcinoma, Squamous Cell

1 location in Pittsburgh

Sponsor: Melissa Pugliano-Mauro

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03370406·Phase 1·Recruiting

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Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

for Obstructive Sleep Apnea of Adult

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: 18+

Code: NCT03487185·Recruiting

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T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

for Sickle Cell Anemia

1 location in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 5 - 40

Code: NCT03653338·Phase 1, Phase 2·Recruiting

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Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

for Systemic Sclerosis

3 locations incl. Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 8 - 60

Code: NCT03630211·Phase 2·Recruiting

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Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria

for Idiopathic Infantile Hypercalcaemia - Severe Form

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 6 Months - 65

Code: NCT03301038·Phase 2·Recruiting

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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

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A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

for Renal Cell Carcinoma

14 locations incl. Phoenix

Sponsor: Xynomic Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT03592472·Phase 3·Recruiting

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A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration

for Age-Related Macular Degeneration

19 locations incl. Phoenix

Sponsor: Astellas Institute for Regenerative Medicine

Sex: All·Age: 50+

Code: NCT03178149·Phase 1·Recruiting

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