Oncology Clinical Trials in Palo Alto, CA

As of June 2026, 129 paid clinical trials are recruiting for Oncology in Palo Alto, California. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 3, 2026.

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129 clinical trials for Oncology

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

Apply to this trial

PrehabPal: A Digital Tool to Help Older Adults Prepare for Cancer Surgery

for Colon Cancer

3 locations incl. Palo Alto

Sponsor: University of California, San Francisco

Sex: All·Age: 65+

Code: NCT05520866·Recruiting

Apply to this trial

Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Drug: Durvalumab

3 locations incl. Palo Alto

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05388006·Phase 2·Recruiting

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Study of CHS-114 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

16 locations incl. Newport Beach

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05635643·Phase 1·Recruiting

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Study to Evaluate Percussive Ventilation Breathhold to Improve Lung Stereotactic Ablative Radiotherapy

for Lung Cancer

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05283564·Recruiting

Apply to this trial

Goals of Care Conversations Study

for Seriously Ill Patients

3 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05001009·Enrolling By Invitation

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

45 locations incl. Goodyear

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting

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A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

for Chronic Lymphocytic Leukemia

Drug: Ibrutinib

19 locations incl. Anaheim

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05254743·Phase 3·Recruiting

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Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

for Advanced Cancer

14 locations incl. Scottsdale

Sponsor: Riboscience, LLC.

Sex: All·Age: 18+

Code: NCT05270213·Phase 1·Recruiting

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A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

8 locations incl. Scottsdale

Sponsor: Peel Therapeutics Inc

Sex: All·Age: 18+

Code: NCT05329103·Phase 1·Recruiting

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Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

for Gastric Cancer

3 locations incl. Palo Alto

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT05274048·Phase 1·Recruiting

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Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

for End of Life

17 locations incl. Birmingham

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT05297734·Recruiting

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Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy

for Follicular Lymphoma

1 location in Palo Alto

Sponsor: Adaptive Biotechnologies

Sex: All·Age: 18+

Code: NCT05255354·Recruiting

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

164 locations incl. Birmingham

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting

Apply to this trial

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

for Cancer

5 locations incl. Duarte

Sponsor: RefleXion Medical

Sex: All·Age: All ages

Code: NCT05406167·Recruiting

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

219 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting

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The Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Cell Transplantation (The RV-BOS Study)

for Bronchiolitis Obliterans Syndrome

4 locations incl. Palo Alto

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 8+

Code: NCT05250037·Recruiting

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Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

for GEP-NET

32 locations incl. Phoenix

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT05477576·Phase 3·Recruiting

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

134 locations incl. Goodyear

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting

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A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

for Leukemia, Myeloid, Acute

33 locations incl. Newport Beach

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 12+

Code: NCT04988555·Phase 1, Phase 2·Recruiting

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A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for Locally Advanced Solid Tumor

20 locations incl. Orange

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05118789·Phase 1, Phase 2·Recruiting

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Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

for Renal Cell Carcinoma (RCC)

46 locations incl. Phoenix

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05176483·Phase 1·Recruiting

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A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

14 locations incl. Palo Alto

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT05125016·Phase 1, Phase 2·Recruiting

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

21 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting

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Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for Solid Tumor, Adult

16 locations incl. Gilbert

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT04981119·Recruiting

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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

for B-cell Malignancy

30 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting

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Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

for Advanced Solid Tumor

10 locations incl. La Jolla

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05007782·Phase 1·Recruiting

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

387 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

621 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

342 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting

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A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

for Solid Tumor

24 locations incl. Tucson

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT04300556·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

1150 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting

Apply to this trial

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia

Drug: Revumenib

22 locations incl. Duarte

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 30 Days+

Code: NCT04065399·Phase 1, Phase 2·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

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Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

for Leukemia, Myeloid, Acute

Drug: Tuspetinib

15 locations incl. Birmingham

Sponsor: Aptose Biosciences Inc.

Sex: All·Age: 18+

Code: NCT03850574·Phase 1, Phase 2·Recruiting

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Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for Solid Tumors

65 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT03486873·Phase 3·Recruiting

Apply to this trial

Panitumumab-IRDye800 in Detecting Cancer in Participants With Lung Cancer During Surgery

for Lung Carcinoma

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 19+

Code: NCT03582124·Phase 1, Phase 2·Recruiting

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

Apply to this trial

Conditions in Oncology (Palo Alto, CA)

Solid tumor· 22 Cancer (any)· 14 Non-small cell lung cancer (NSCLC)· 11 Breast cancer· 9 Ovarian cancer· 7 Acute myeloid leukemia (AML)· 7 Chronic lymphocytic leukemia (CLL)· 7 Leukemia (other)· 7 Myelodysplastic syndromes (MDS)· 7 Non-Hodgkin lymphoma· 7 Small lymphocytic lymphoma· 7 Pancreatic cancer· 6 Colorectal cancer· 5 Metastatic prostate cancer· 5 Head and neck cancer· 5 Osteosarcoma· 5 Neuroblastoma· 5 Lung cancer· 4 Gastric cancer· 4 Prostate cancer· 4 Endometrial cancer· 4 Acute lymphoblastic leukemia· 4 Diffuse large B-cell lymphoma (DLBCL)· 4 Metastatic breast cancer· 3 Liver cancer· 3 Kidney cancer· 3 Multiple myeloma· 3 Follicular lymphoma· 3 Mantle cell lymphoma· 3 Hematologic malignancy· 3 Melanoma· 3 Biliary tract cancer· 2 Fallopian tube cancer· 2 Marginal zone lymphoma· 2 Soft tissue sarcoma· 2 Neuroendocrine tumors· 2 Triple-negative breast cancer· 1 Colon cancer· 1 Esophageal cancer· 1 Gastroesophageal junction cancer· 1 Gastrointestinal cancer· 1 Bladder cancer· 1 Cervical cancer· 1 Uterine cancer· 1 Gynecologic cancer· 1 Glioblastoma· 1 Glioma· 1 Brain metastases· 1 Chronic myelomonocytic leukemia· 1 Myelofibrosis· 1 Myeloproliferative neoplasm· 1 Hodgkin lymphoma· 1 Burkitt lymphoma· 1 Sarcoma· 1 Ewing sarcoma· 1 Rhabdomyosarcoma· 1 Mesothelioma· 1