Paid Clinical Trials in Philadelphia, PA

As of July 2026, 1,975 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

1,726 clinical trials

A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings

for Functional Impairment

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT06404970·Recruiting·Listed May 2024

Apply to this trial

Short Course Radiotherapy

for Central Nervous System Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: Up to 21

Code: NCT07147179·Recruiting·Listed Aug 2025

Apply to this trial

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

for Colorectal Carcinoma

Sites in Philadelphia +8 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05410977·Recruiting·Listed Jun 2022

Apply to this trial

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

for SLE

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12 - 29

Code: NCT06839976·Phase 1, Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Tocilizumab in Lung Transplantation

for Lung Transplant

Drug: Tocilizumab

Sites in Philadelphia +16 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 75

Code: NCT06033196·Phase 2·Recruiting·Listed Sep 2023

Apply to this trial

Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

for Pediatric Patients Treated With Radiation Therapy

Sites in Philadelphia +22 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: Up to 21

Code: NCT01696721·Recruiting·Listed Oct 2012

Apply to this trial

Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Philadelphia, Hershey +58 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

Apply to this trial

Quantifying New Heart Muscle Cells

for Tetralogy of Fallot With Pulmonary Stenosis

Sites in Philadelphia, Pittsburgh +2 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 30 Days - 1

Code: NCT06587165·Recruiting·Listed Sep 2024

Apply to this trial

QOL and Sarcopenia in Patients With Ascites

for Ascites Hepatic

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05726747·Recruiting·Listed Feb 2023

Apply to this trial

Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention

for Sepsis

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 17

Code: NCT07084129·Phase 1·Recruiting·Listed Jul 2025

Apply to this trial

Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants

for Williams Beuren Syndrome

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06930417·Recruiting·Listed Apr 2025

Apply to this trial

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Philadelphia, Pittsburgh +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

Apply to this trial

Neoadjuvant Tebentafusp for Uveal Melanoma

for Locally Advanced Unresectable Uveal Melanoma

Drug: Tebentafusp

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06414590·Phase 2·Recruiting·Listed May 2024

Apply to this trial

A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program

for Obesity

Sites in Philadelphia +2 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 25 - 59

Code: NCT05748158·Recruiting·Listed Feb 2023

Apply to this trial

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

for Sleep Disturbance

Sites in Philadelphia & Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 18

Code: NCT06963463·Recruiting·Listed May 2025

Apply to this trial

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in Philadelphia, Allentown +161 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

Apply to this trial

Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism

for Hyperparathyroidism, Primary

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06562881·Recruiting·Listed Aug 2024

Apply to this trial

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

for Diffuse Midline Glioma (DMG)

Sites in Philadelphia +4 more locations

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 2 - 21

Code: NCT04732065·Phase 1·Recruiting·Listed Feb 2021

Apply to this trial

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

for Non-small Cell Lung Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04332367·Phase 2·Recruiting·Listed Apr 2020

Apply to this trial

NEPTUNE Match Study

for Nephrotic Syndrome in Children

Sites in Philadelphia +15 more locations

Sponsor: University of Michigan

Sex: All·Age: 1 - 80

Code: NCT04571658·Recruiting·Listed Oct 2020

Apply to this trial

Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients

for Autoimmune Lymphoproliferative Syndrome

Drug: Soquelitinib

Sites in Philadelphia +2 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 16 - 120

Code: NCT06730126·Phase 2·Recruiting·Listed Dec 2024

Apply to this trial

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

for Hematologic Neoplasms

Sites in Philadelphia +1 more location

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 85·Accepts healthy volunteers

Code: NCT04959175·Phase 1, Phase 2·Recruiting·Listed Jul 2021

Apply to this trial

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

Sites in Philadelphia, Willow Grove +144 more locations

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting·Listed Aug 2024

Apply to this trial

Synovial Sarcoma Registry / Biospecimen Repository

for Synovial Sarcoma

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT05910307·Recruiting·Listed Jun 2023

Apply to this trial

Triage Survey for Psychiatry Research Eligibility

for Major Depressive Disorder

Sites in Philadelphia +5 more locations

Sponsor: Adams Clinical

Sex: All·Age: 18+

Code: NCT05800925·Recruiting·Listed Apr 2023

Apply to this trial

A Registry for People With T-cell Lymphoma

for T-cell Lymphoma

Sites in Philadelphia +25 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: All ages

Code: NCT05978141·Recruiting·Listed Aug 2023

Apply to this trial

The Periviable GOALS Decision Support Tool

for Pregnancy Preterm

Sites in Philadelphia +11 more locations

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05264779·Recruiting·Listed Mar 2022

Apply to this trial

Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

for Stress Urinary Incontinence

Sites in Philadelphia +6 more locations

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 21+

Code: NCT06480227·Recruiting·Listed Jun 2024

Apply to this trial

Prokinetics and Body Surface Gastric Mapping in Dyspeptic Patients: Baseline and Treatment Effects

for Gastroparesis

1 location in Philadelphia

Sponsor: University of Auckland, New Zealand

Sex: All·Age: 18+

Code: NCT06854120·Recruiting·Listed Mar 2025

Apply to this trial

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

for Cystic Fibrosis

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04731272·Phase 2·Recruiting·Listed Jan 2021

Apply to this trial

Targeted Immunotherapy After Myeloablative TBI-Based Conditioning & AlloHCT in CAYA With High Risk T-Cell ALL & Lymphoma

for T-cell Acute Lymphoblastic Leukemia

Sites in Philadelphia +15 more locations

Sponsor: New York Medical College

Sex: All·Age: Up to 39

Code: NCT04972942·Phase 1·Recruiting·Listed Jul 2021

Apply to this trial

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

for Bone Pain

Sites in Philadelphia +8 more locations

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT03858205·Recruiting·Listed Feb 2019

Apply to this trial

Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients

for BK Polyomavirus

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 5 Weeks - 25

Code: NCT04293042·EARLY_Phase 1·Recruiting·Listed Mar 2020

Apply to this trial

[18F]FES PET/.CT in Uterine Cancer

for Uterine Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT05916196·Phase 2·Recruiting·Listed Jun 2023

Apply to this trial

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

Sites in Philadelphia, Wilkes-Barre +114 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting·Listed Sep 2023

Apply to this trial

CapTemY90 for Grade 2/3 NET Liver Metastases

for Neuroendocrine Tumor Grade 2

Sites in Philadelphia +3 more locations

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04339036·Phase 2·Recruiting·Listed Apr 2020

Apply to this trial

Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention

for Suicide and Depression

Sites in Philadelphia, Springfield +11 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 18

Code: NCT05748730·Recruiting·Listed Mar 2023

Apply to this trial

Flu Infection at UPHS

for Influenza Human

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06807840·Recruiting·Listed Feb 2025

Apply to this trial

Improving Heart Health in Individuals With SCI Using Home-Based Virtual Gaming

for Spinal Cord Injuries (SCI)

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18+

Code: NCT06690372·Recruiting·Listed Nov 2024

Apply to this trial

Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections

for Gonorrhea

Sites in Philadelphia +12 more locations

Sponsor: Westat

Sex: Female·Age: 13 - 29

Code: NCT06738407·Phase 4·Recruiting·Listed Dec 2024

Apply to this trial