Paid Clinical Trials in Philadelphia, PA

As of July 2026, 1,975 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,726 clinical trials

Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial

for Acute Respiratory Distress Syndrome (ARDS)

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 Weeks - 17

Code: NCT07123961·Phase 2·Recruiting·Listed Aug 2025

Apply to this trial

Re-Engaging AYA Survivors in Cancer-Related Healthcare

for Cancer

Sites in Philadelphia +2 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 15 - 29

Code: NCT07138040·Recruiting·Listed Aug 2025

Apply to this trial

Massage Impact on Sleep in Pediatric Oncology

for Cancer

Sites in Philadelphia +1 more location

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12 - 21

Code: NCT06892158·Recruiting·Listed Mar 2025

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Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

for Chronic Kidney Disease

Sites in Philadelphia +1 more location

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 6 Months - 22

Code: NCT00327860·Recruiting·Listed May 2006

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Fontan Fitness Trial

for Single-ventricle

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 17

Code: NCT06918795·Recruiting·Listed Apr 2025

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Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

for Leukemia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 25

Code: NCT06839456·Phase 1, Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial

for Heart Failure With Preserved Ejection Fraction

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05138575·Phase 2·Recruiting·Listed Dec 2021

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Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma

for Hepatocellular Carcinoma

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05842174·Phase 1, Phase 2·Recruiting·Listed May 2023

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ALS20-101 Lentiviral Gene Therapy for Beta Thalassemia

for Beta-Thalassemia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18 - 40

Code: NCT06364774·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH

for Developmental Dysplasia of the Hip

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 4 Months - 24 Months

Code: NCT03107520·EARLY_Phase 1·Recruiting·Listed Apr 2017

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Pencil Beam Scanning in Patients With Renal Tumors

for Renal Tumor

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 30

Code: NCT03810651·EARLY_Phase 1·Recruiting·Listed Jan 2019

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Adaptive Radiation Boost for Rectal Cancer

for Rectum Cancer, Adenocarcinoma

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07221058·Phase 1·Recruiting·Listed Oct 2025

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Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

for Metastatic Prostate Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Male·Age: 18+

Code: NCT05487846·Recruiting·Listed Aug 2022

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Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

for Childhood Fibrolamellar Carcinoma

Sites in Philadelphia, Pittsburgh +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 39

Code: NCT06620302·Phase 1, Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

MAGIC Ruxolitinib for aGVHD

for Acute Graft-versus-host Disease

Drug: Ruxolitinib

Sites in Philadelphia +13 more locations

Sponsor: John Levine

Sex: All·Age: 18+

Code: NCT06936566·Phase 2·Recruiting·Listed Apr 2025

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ETHAN - ET for Male BC

for Male Breast Cancer

Sites in Philadelphia, Pittsburgh +6 more locations

Sponsor: Jose Pablo Leone

Sex: Male·Age: 18+

Code: NCT05501704·Phase 2·Recruiting·Listed Aug 2022

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Nerve Transfer to Improve Function in High Level Tetraplegia

for Cervical Spinal Cord Injury

Sites in Philadelphia +8 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT06288763·Recruiting·Listed Mar 2024

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Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

for Delirium

Sites in Philadelphia, Pittsburgh +5 more locations

Sponsor: University of Michigan

Sex: All·Age: 70+

Code: NCT05929703·Recruiting·Listed Jul 2023

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Neuroblastoma Biology Study

for Neuroblastoma

Sites in Philadelphia +13 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting·Listed Apr 2012

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Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

Sites in Philadelphia, Pittsburgh +21 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting·Listed Jul 2025

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Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

Sites in Philadelphia, Pittsburgh +16 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting·Listed May 2024

Apply to this trial

EVR and EPO for Liver Transplant Tolerance

for Liver Transplant

Sites in Philadelphia +2 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06832189·Phase 1·Recruiting·Listed Feb 2025

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Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

for Suspected Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT02637934·Phase 1·Recruiting·Listed Dec 2015

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Collection of Circulating Biomarkers in Pancreatic Cancer

for Pancreas Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05743049·Recruiting·Listed Feb 2023

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

Sites in Philadelphia, Lancaster +71 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting·Listed Apr 2024

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A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

for Amblyopia

Sites in Philadelphia, Lancaster +66 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 3 - 13

Code: NCT04378790·Phase 3·Recruiting·Listed May 2020

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Adolescent Outcomes of Post-operative Opioid EXposure

for Opioid Use Disorder

Sites in Philadelphia +4 more locations

Sponsor: Sharon Levy

Sex: All·Age: 12 - 17

Code: NCT06350409·Recruiting·Listed Apr 2024

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A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for High Grade Glioma

Sites in Philadelphia +8 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04655404·EARLY_Phase 1·Recruiting·Listed Dec 2020

Apply to this trial

Transformative Research in Diabetic Nephropathy

for Diabetic Nephropathies

Sites in Philadelphia, Allentown +11 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 100

Code: NCT02986984·Recruiting·Listed Dec 2016

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RemI for Post-Bariatric Surgery Weight Regain

for Obesity

Sites in Philadelphia +1 more location

Sponsor: Temple University

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06292936·Recruiting·Listed Mar 2024

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Driver Education Research Study

for Risk Reduction Behavior

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 16 - 17·Accepts healthy volunteers

Code: NCT06413927·Recruiting·Listed May 2024

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Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

for Malignant Solid Neoplasm

Sites in Philadelphia +1 more location

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18+

Code: NCT06306638·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)

for Hip Fractures

Sites in Philadelphia +5 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 50+

Code: NCT06438640·Recruiting·Listed Jun 2024

Apply to this trial

Penn Medicine Healthy Heart

for Hypertension

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 35 - 80

Code: NCT06062394·Recruiting·Listed Oct 2023

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Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms

for Gastroparesis

Sites in Philadelphia +4 more locations

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT04661215·Recruiting·Listed Dec 2020

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Gastroparesis Registry 4

for Gastroparesis

Sites in Philadelphia +5 more locations

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 85

Code: NCT05846802·Recruiting·Listed May 2023

Apply to this trial

Social Groups for Autistic Young Adults (SDARIYA)

for Autism Spectrum Disorder

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 30

Code: NCT07222982·Recruiting·Listed Oct 2025

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Longitudinal Assessment of Traumatic Microvascular Injury-2

for Traumatic Brain Injury

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05725993·Recruiting·Listed Feb 2023

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Lurbinectedin in FET-Fused Tumors

for Ewing Sarcoma

Drug: Lurbinectedin

Sites in Philadelphia +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10+

Code: NCT05918640·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

for Pediatric Sarcoma, Refractory

Sites in Philadelphia +21 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 2 - 40

Code: NCT05634369·Phase 1, Phase 2·Recruiting·Listed Dec 2022

Apply to this trial