Paid Clinical Trials in Philadelphia, PA

As of July 2026, 1,975 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,726 clinical trials

SBRT With Atezo/Bev for HCC

for Hepatocellular Carcinoma

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18 - 99

Code: NCT05488522·Phase 1·Recruiting·Listed Aug 2022

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The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

for Smoking

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06264154·Recruiting·Listed Feb 2024

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Validation of Nanosensor Oxygen Measurement

for MItochondrial Myopathies

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06819683·Phase 1·Recruiting·Listed Feb 2025

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External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients

for Sepsis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT04855786·Recruiting·Listed Apr 2021

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Virtual Reality 3D-Surgery Modeling to Enhance Head and Neck Cancer Surgery Quality

for Head and Neck Squamous Cell Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05031910·Recruiting·Listed Sep 2021

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Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation

for Recurrent Renal Cell Carcinoma

1 location in Philadelphia

Sponsor: john eisenbrey

Sex: All·Age: 18+

Code: NCT05641935·Phase 2·Recruiting·Listed Dec 2022

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Contrast Enhanced Ultrasound to Evaluate Response to Chemoembolization in Patients With Liver Tumors

for Liver Neoplasms

1 location in Philadelphia

Sponsor: john eisenbrey

Sex: All·Age: 18+

Code: NCT06261814·Phase 2·Recruiting·Listed Feb 2024

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One-Time DNA Study for Vasculitis

for Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: All·Age: 7+

Code: NCT01241305·Recruiting·Listed Nov 2010

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VCRC Tissue Repository

for Aortitis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT02967068·Recruiting·Listed Nov 2016

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Maternal Newborn Health Registry

for Pregnancy Outcome Trends in Low-resource Geographic Areas

Sites in Philadelphia +7 more locations

Sponsor: NICHD Global Network for Women's and Children's Health

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01073475·Recruiting·Listed Feb 2010

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Healthy Volunteers Study

for Ovarian Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 30 - 50·Accepts healthy volunteers

Code: NCT06962059·Recruiting·Listed May 2025

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Brief Behavioral Sleep Intervention for Obesity Prevention in Primary Care

for Obesity, Childhood

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 6 - 11

Code: NCT06810557·Recruiting·Listed Feb 2025

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Localizing Epileptic Networks Using MRI and iEEG

for Epilepsy

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04649008·EARLY_Phase 1·Recruiting·Listed Dec 2020

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Biobehavioral Reward Responses Associated With Consumption of Nutritionally Diverse Ultra-Processed Foods

for Obesity

1 location in Philadelphia

Sponsor: Oregon Research Institute

Sex: All·Age: 18 - 65

Code: NCT05437809·Recruiting·Listed Jun 2022

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Reducing Patient Memory Recall in the Burning Mouth Patient Population

for Burning Mouth Syndrome

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05819697·Recruiting·Listed Apr 2023

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Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma

for Neuroblastoma

Sites in Philadelphia +5 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 17

Code: NCT06831552·Recruiting·Listed Feb 2025

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An Open-Label Study of Effectiveness of Immunomodulatory Medications for Patients With Relapsing Polychondritis

for Relapsing Polychondritis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06941376·Phase 2·Recruiting·Listed Apr 2025

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Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy

for Hypertrophic Cardiomyopathy Without Obstruction

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06433050·EARLY_Phase 1·Recruiting·Listed May 2024

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Validation of Oxygen Nanosensor in Mitochondrial Myopathy

for Mitochondrial Myopathies

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT04086329·Phase 1·Recruiting·Listed Sep 2019

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PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial

for Lung Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05775939·Recruiting·Listed Mar 2023

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BSGM to Evaluate Patients With GI Symptoms

for Gastrointestinal Motility Disorders in Children

Sites in Philadelphia +4 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 8 - 25·Accepts healthy volunteers

Code: NCT05880199·Recruiting·Listed May 2023

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Neurometabolic Profile of Individuals With Primary Mitochondrial Disease

for Primary Mitochondrial Disease

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 8 - 75·Accepts healthy volunteers

Code: NCT06890520·Recruiting·Listed Mar 2025

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Home Blood Transfusions

for Hematologic Malignancy

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07121140·Recruiting·Listed Aug 2025

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FAPI-74 PET/CT in Adults With Fibrosis

for Fibrosis (Morphologic Abnormality)

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 21+

Code: NCT06413355·Phase 1·Recruiting·Listed May 2024

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Ketone Ester Intervention in Alcohol Use Disorder

for Alcohol Drinking

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT04616781·Phase 2, Phase 3·Recruiting·Listed Nov 2020

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SKIP for PA Study: Team and Leadership Level Implementation Support for Collaborative Care

for Child Behavior Problem

Sites in Philadelphia & Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04946253·Recruiting·Listed Jun 2021

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Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults

for Influenza, Human

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05108818·Phase 4·Recruiting·Listed Nov 2021

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The Myelin Disorders Biorepository Project

for Leukodystrophy

Sites in Philadelphia, Pittsburgh +21 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting·Listed Feb 2017

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Left vs Left Randomized Clinical Trial

for Heart Failure

Sites in Philadelphia, Allentown +55 more locations

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting·Listed Dec 2022

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Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

for Relapsing Multiple Sclerosis

Sites in Philadelphia +19 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT04047628·Phase 3·Recruiting·Listed Aug 2019

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Prospective 4D CTA of BAV Competence

for Bicuspid

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04645862·Recruiting·Listed Nov 2020

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Hypofractionated WPPT With HDR Boost

for Prostate Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06591819·Phase 2·Recruiting·Listed Sep 2024

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Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

for Pancreatic Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT02478892·Recruiting·Listed Jun 2015

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CTNNA1 Familial Expansion Study

for Cancer Gene Mutation

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05126290·Recruiting·Listed Nov 2021

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Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal

for Opiate Withdrawal Syndrome

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05995535·Phase 2·Recruiting·Listed Aug 2023

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Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy

for Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07167446·EARLY_Phase 1·Recruiting·Listed Sep 2025

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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

Sites in Philadelphia +27 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting·Listed Jun 2021

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Comparing Antibiotic Treatment Strategies for Children With Pneumonia in Outpatient Settings: (STAMPP)

for Community Acquired Pneumonia (CAP)

Sites in Philadelphia +3 more locations

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 12 Months - 71 Months

Code: NCT06986148·Recruiting·Listed May 2025

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Philadelphia, Hershey +66 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

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National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

Sites in Philadelphia +17 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting·Listed Oct 2023

Apply to this trial