Paid Clinical Trials in Philadelphia, PA

As of August 2026, 1,975 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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1,738 clinical trials

PET Tau - Neurodegenerative Disease Imaging

for Neurodegenerative Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT03143374·Phase 2, Phase 3·Recruiting·Listed May 2017

Apply to this trial

Postpartum Care in the NICU (PeliCaN) Transitions

for Stress Disorders, Post-Traumatic

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 16+

Code: NCT06521398·Recruiting·Listed Jul 2024

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The Cancer of the Pancreas Screening-5 CAPS5)Study

for Pancreas Cancer

Sites in Philadelphia, Pittsburgh +7 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT02000089·Phase 3·Recruiting·Listed Dec 2013

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Parkinson's Disease and Movement Disorders Clinical Database

for Parkinson Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04997642·Recruiting·Listed Aug 2021

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Imaging Retinal Vasculature in Infant Eyes

for Retinopathy of Prematurity

Sites in Philadelphia +1 more location

Sponsor: Duke University

Sex: All·Age: Up to 2 Months

Code: NCT05558059·Recruiting·Listed Sep 2022

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Physical Activity in CKD

for Chronic Kidney Diseases

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 13 - 18

Code: NCT06624358·Recruiting·Listed Oct 2024

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Remote Sputum Collection in Cystic Fibrosis

for Cystic Fibrosis

Sites in Philadelphia +2 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06950892·Recruiting·Listed Apr 2025

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Cord Clamping Among Neonates With Congenital Heart Disease

for Congenital Heart Disease (CHD)

Sites in Philadelphia +17 more locations

Sponsor: Carl Backes, MD

Sex: All·Age: 37 Weeks - 42 Weeks

Code: NCT06153459·Recruiting·Listed Dec 2023

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Using the EHR to Advance Genomic Medicine Across a Diverse Health System

for Genetic Predisposition

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06377033·Recruiting·Listed Apr 2024

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T1D Pregnancy & Me

for Diabetes Mellitus, Type 1

Sites in Philadelphia +9 more locations

Sponsor: Jaeb Center for Health Research

Sex: Female·Age: 18+

Code: NCT06959316·Recruiting·Listed May 2025

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Intravesical Treatment of Bladder Cancer at Home, Multi-modal Treatment Support

for Bladder Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07048496·Recruiting·Listed Jul 2025

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A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

Sites in Philadelphia +9 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting·Listed Jun 2025

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Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

for Urothelial Carcinoma

2 locations in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07043972·Phase 2·Recruiting·Listed Jun 2025

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Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

for Systemic Lupus Erythematosus

1 location in Philadelphia

Sponsor: Stephan Grupp MD PhD

Sex: All·Age: 8 - 25

Code: NCT05029336·Phase 2·Recruiting·Listed Aug 2021

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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

Sites in Philadelphia, Pittsburgh +50 more locations

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting·Listed Apr 2012

Apply to this trial

Philly CEAL- DECIDE+ Adaptation

for Disparities

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 35 - 75·Accepts healthy volunteers

Code: NCT06732102·Recruiting·Listed Dec 2024

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Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

for Smoking, Cigarette

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT03721822·Phase 1·Recruiting·Listed Oct 2018

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Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

Sites in Philadelphia, Kingston +25 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting·Listed Jul 2021

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Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

for Heart Failure

Sites in Philadelphia +3 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06291922·Recruiting·Listed Mar 2024

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Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy

for Pancreatic Adenocarcinoma Metastatic

Drug: Ipilimumab

Sites in Philadelphia +1 more location

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06747845·Phase 2·Recruiting·Listed Dec 2024

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MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction

for HFpEF - Heart Failure With Preserved Ejection Fraction

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06670001·Recruiting·Listed Nov 2024

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Evaluation of the PACE/PACENET BHL Clinical Program

for Depression

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 65+

Code: NCT02463266·Recruiting·Listed Jun 2015

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Studying Health Outcomes After Treatment in Patients With Retinoblastoma

for Retinoblastoma

Sites in Philadelphia +9 more locations

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT03932786·Recruiting·Listed May 2019

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Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)

for Giant Cell Arteritis

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT05865054·Recruiting·Listed May 2023

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Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65

Code: NCT06559995·Phase 2, Phase 3·Recruiting·Listed Aug 2024

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Posterior Cingulate Cortex and Executive Control of Episodic Memory

for Episodic Memory

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 50

Code: NCT06540976·Recruiting·Listed Aug 2024

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Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children

for Pediatric ALL

Sites in Philadelphia +2 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 4 Weeks - 18

Code: NCT06529575·Recruiting·Listed Jul 2024

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Oral Nutritional Optimization in Total Joint Arthroplasty

for Osteoarthritis

Sites in Philadelphia +1 more location

Sponsor: NYU Langone Health

Sex: All·Age: 55+

Code: NCT04210284·Recruiting·Listed Dec 2019

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Ovarian Tissue Transplantation

for Infertile Females or Females With Ovarian Insufficiency

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18 - 45

Code: NCT01870752·Recruiting·Listed Jun 2013

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Natural History Study of Mitochondrial Myopathy

for Primary Mitochondrial Disease

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 100·Accepts healthy volunteers

Code: NCT05250375·Recruiting·Listed Feb 2022

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Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

for Sickle Cell Disease

Sites in Philadelphia +8 more locations

Sponsor: RTI International

Sex: All·Age: 18+

Code: NCT06385886·Recruiting·Listed Apr 2024

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Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

for Friedreich Ataxia

Sites in Philadelphia +8 more locations

Sponsor: Friedreich's Ataxia Research Alliance

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06016946·Recruiting·Listed Aug 2023

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Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure

for Atrial Fibrillation (AF)

Sites in Philadelphia +5 more locations

Sponsor: McMaster University

Sex: All·Age: 18+

Code: NCT06957366·Recruiting·Listed May 2025

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Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

for Relapsed/Refractory KMT2A-r Acute Leukemia

Sites in Philadelphia +10 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 0 - 21

Code: NCT06376162·Phase 1·Recruiting·Listed Apr 2024

Apply to this trial

Videos to Aid Decision Making for Fibroid Treatment

for Uterine Bleeding

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 55

Code: NCT07072364·Recruiting·Listed Jul 2025

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Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

for Alzheimer's Disease

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 120

Code: NCT05658913·Recruiting·Listed Dec 2022

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Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis

for FAP

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06578637·Recruiting·Listed Aug 2024

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Decoding and Modulating Affective Brain States

for Rumination

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65

Code: NCT05437705·Recruiting·Listed Jun 2022

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The Pediatric Anesthesia Quality Improvement Project

for Surgery

Sites in Philadelphia, Hershey +35 more locations

Sponsor: The Society for Pediatric Anesthesia

Sex: All·Age: Up to 21

Code: NCT00674388·Recruiting·Listed May 2008

Apply to this trial

Trauma Resuscitation With Low-Titer Group O Whole Blood or Products

for Wounds and Injuries

Sites in Philadelphia +12 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 15+

Code: NCT05638581·Phase 3·Recruiting·Listed Dec 2022

Apply to this trial