Clinical Trials at Children's Hospital of Pittsburgh of UPMC

As of July 2026, 57 paid clinical trials are recruiting at Children's Hospital of Pittsburgh of UPMC, located at 3705 5TH AVE, PITTSBURGH, PA 15213-2584, phone (412) 692-6207 in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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58 clinical trials at Children's Hospital of Pittsburgh of UPMC

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

Sites in Pittsburgh, Philadelphia +17 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting·Listed Feb 2024

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Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

for Acute Biphenotypic Leukemia

Sites in Pittsburgh +8 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 6 Months - 26·Accepts healthy volunteers

Code: NCT03779854·Phase 2·Recruiting·Listed Dec 2018

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CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

for Diffuse Midline Glioma, H3 K27-Altered

Sites in Pittsburgh, Philadelphia +32 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 21

Code: NCT04870944·Phase 1, Phase 2·Recruiting·Listed May 2021

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Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

for Solid Tumor

Sites in Pittsburgh +2 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 20

Code: NCT05645523·EARLY_Phase 1·Recruiting·Listed Dec 2022

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Pittsburgh, Hershey +143 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

for Childhood Fibrolamellar Carcinoma

Sites in Pittsburgh, Philadelphia +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 39

Code: NCT06620302·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

Sites in Pittsburgh, Philadelphia +20 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting·Listed Oct 2024

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Exome and Genome Analysis to Elucidate Genetic Etiologies and Population Characteristics in the Plain Community

for Undiagnosed Disease

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: Up to 100·Accepts healthy volunteers

Code: NCT02927158·Recruiting·Listed Oct 2016

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Neurogenetics Patient Registry

for Neurogenetic Disorders

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT02995538·Recruiting·Listed Dec 2016

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Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

for Recurrent T Acute Lymphoblastic Leukemia

Sites in Pittsburgh, Philadelphia +112 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 12+

Code: NCT04315324·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

for Idiopathic Pulmonary Fibrosis

2 locations in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 18 - 60

Code: NCT03500731·Phase 1, Phase 2·Recruiting·Listed Apr 2018

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A Vaccine Trial for Low Grade Gliomas

for Low Grade Glioma

1 location in Pittsburgh

Sponsor: James Felker

Sex: All·Age: 12 Months - 21

Code: NCT02358187·Phase 2·Recruiting·Listed Feb 2015

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Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

for Systemic Sclerosis

3 locations in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 8 - 60

Code: NCT03630211·Phase 2·Recruiting·Listed Aug 2018

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HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

for Hydrocephalus

Sites in Pittsburgh +14 more locations

Sponsor: University of Utah

Sex: All·Age: 1 Day - 104 Weeks

Code: NCT04177914·Phase 3·Recruiting·Listed Nov 2019

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Biomarkers in Transplant Recipients to Improve Outcomes

for Solid Organ Transplantation

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT01163578·Recruiting·Listed Jul 2010

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TrialNet Pathway to Prevention of T1D

for Diabetes Mellitus, Type 1

Sites in Pittsburgh +16 more locations

Sponsor: University of South Florida

Sex: All·Age: 2 - 45·Accepts healthy volunteers

Code: NCT00097292·Recruiting·Listed Nov 2004

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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

Sites in Pittsburgh, Harrisburg +57 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting·Listed Aug 2016

Apply to this trial