Paid Clinical Trials in Pittsburgh, PA

As of August 2026, 1,248 paid clinical trials are recruiting in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 12, 2026.

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1,097 clinical trials

Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study

for Prostate Adenocarcinoma

Sites in Pittsburgh +1 more location

Sponsor: University of Washington

Sex: Male·Age: 18+

Code: NCT04175431·Phase 2·Recruiting·Listed Nov 2019

Apply to this trial

Acetazolamide for Treatment Resistant Schizophrenia

for Schizophrenia

1 location in Pittsburgh

Sponsor: Vishwajit Nimgaonkar, MD PhD

Sex: All·Age: 18 - 55

Code: NCT04887792·Phase 1, Phase 2·Recruiting·Listed May 2021

Apply to this trial

Autologous Dendritic Cell Vaccine in Kidney Cancer

for Carcinoma, Renal Cell

1 location in Pittsburgh

Sponsor: Jodi Maranchie

Sex: All·Age: 18+

Code: NCT05127824·Phase 2·Recruiting·Listed Nov 2021

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CPI-0209 Plus Carboplatin in Patients With Platinum Sensitive Recurrent Ovarian Cancer

for Recurrent Ovarian Cancer

1 location in Pittsburgh

Sponsor: Lan Coffman

Sex: Female·Age: 18+

Code: NCT05942300·Phase 1·Recruiting·Listed Jul 2023

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Imaging CRF X NOP Interactions in CUD

for Cocaine Use Disorder

1 location in Pittsburgh

Sponsor: Rajesh Narendran

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT05008146·EARLY_Phase 1·Recruiting·Listed Aug 2021

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[C-11]NPA PET-amphetamine in Cocaine Use Disorders

for Cocaine Use Disorder

1 location in Pittsburgh

Sponsor: Rajesh Narendran

Sex: All·Age: 18 - 55

Code: NCT05011760·EARLY_Phase 1·Recruiting·Listed Aug 2021

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

Sites in Pittsburgh, Philadelphia +78 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting·Listed Aug 2023

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

Sites in Pittsburgh, Hershey +132 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020

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TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

for Breast Cancer

Sites in Pittsburgh, State College +2 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 65+

Code: NCT05535192·Recruiting·Listed Sep 2022

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Digital Maternal Support Tool Implementation

for Postpartum

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18 - 45

Code: NCT07295015·Recruiting·Listed Dec 2025

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Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness

for Schizophrenia

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 70

Code: NCT05157620·Recruiting·Listed Dec 2021

Apply to this trial

Get ActivE Study for At-risk Youth

for Anhedonia

Sites in Pittsburgh & Philadelphia

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 18

Code: NCT06829953·Recruiting·Listed Feb 2025

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Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

for Clinical Stage III Cutaneous Melanoma AJCC v8

Sites in Pittsburgh +24 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05896839·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

Sites in Pittsburgh, Philadelphia +17 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting·Listed Sep 2021

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Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

for Opioid Withdrawal

1 location in Pittsburgh

Sponsor: Payel Roy

Sex: All·Age: 18+

Code: NCT07079826·Recruiting·Listed Jul 2025

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Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder

for Central Sleep Apnea Comorbid With Opioid Use

1 location in Pittsburgh

Sponsor: Sanjay R Patel

Sex: All·Age: 18 - 100

Code: NCT06521476·Phase 2·Recruiting·Listed Jul 2024

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TERPS Trial for de Novo Oligometastic Prostate Cancer

for Prostate Cancer

Sites in Pittsburgh, Philadelphia +8 more locations

Sponsor: University of Maryland, Baltimore

Sex: Male·Age: 18+

Code: NCT05223803·Phase 2·Recruiting·Listed Feb 2022

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Dietary Interventions in Cancer Patients Treated With Immune Checkpoint Inhibitors

for Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06475807·Recruiting·Listed Jun 2024

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Pittsburgh, Wyomissing +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

Sites in Pittsburgh, Philadelphia +67 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting·Listed Jan 2023

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Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation

for Repetitive Head Impacts

1 location in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 30 - 70

Code: NCT07050173·Phase 1·Recruiting·Listed Jul 2025

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ALS/MND Natural History Study Data Repository

for ALS

Sites in Pittsburgh, Philadelphia +12 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

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University of Pittsburgh Brain Health Initiative

for Traumatic Brain Injury

1 location in Pittsburgh

Sponsor: David Okonkwo, MD, PhD

Sex: Male·Age: 29 - 59·Accepts healthy volunteers

Code: NCT04708613·Recruiting·Listed Jan 2021

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Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

for Pancreatic Carcinoma

Sites in Pittsburgh +7 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06271291·Recruiting·Listed Feb 2024

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Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

Sites in Pittsburgh +17 more locations

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting·Listed Nov 2019

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Pittsburgh, Philadelphia +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

for Childhood Astrocytoma

Sites in Pittsburgh, Philadelphia +18 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 22

Code: NCT06894979·Phase 1·Recruiting·Listed Mar 2025

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Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke

for Stroke

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06458153·Recruiting·Listed Jun 2024

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Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

for Opioid-use Disorder

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All·Age: 22 - 65

Code: NCT04354077·Recruiting·Listed Apr 2020

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Machine-Learning Prediction and Reducing Overdoses With EHR Nudges

for Opioid Overdose

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06806163·Recruiting·Listed Feb 2025

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Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)

for Esophageal Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06872515·Recruiting·Listed Mar 2025

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Study of Individuals Affected With Hypoplasminogenemia

for Plasminogen Deficiency

Sites in Pittsburgh +10 more locations

Sponsor: Indiana Hemophilia &Thrombosis Center, Inc.

Sex: All·Age: All ages

Code: NCT03797495·Recruiting·Listed Jan 2019

Apply to this trial

Quantifying New Heart Muscle Cells

for Tetralogy of Fallot With Pulmonary Stenosis

Sites in Pittsburgh, Philadelphia +2 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 30 Days - 1

Code: NCT06587165·Recruiting·Listed Sep 2024

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Pittsburgh, Hershey +58 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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MyPaTH Story Booth

for Narrative Medicine

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 99

Code: NCT03494075·Recruiting·Listed Apr 2018

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Active Surveillance in Older Women With ER+ Breast Cancer

for Early Stage Estrogen Receptor (ER) Positive Breast Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 70+

Code: NCT07262138·Recruiting·Listed Dec 2025

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Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

for Sleep Disturbance

Sites in Pittsburgh & Philadelphia

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 18

Code: NCT06963463·Recruiting·Listed May 2025

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Pittsburgh, Philadelphia +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in Pittsburgh, Hershey +161 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

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A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

for Graft-Versus-Host Disease

Sites in Pittsburgh +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 4+

Code: NCT05675930·Phase 2·Recruiting·Listed Jan 2023

Apply to this trial