Paid Clinical Trials in Plano, TX

As of July 2026, 167 paid clinical trials are recruiting in Plano, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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142 clinical trials

Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

for Ascending Aortic Aneurysm Enlargement

Sites in Plano, Houston +13 more locations

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18 - 79

Code: NCT03536312·Recruiting·Listed May 2018

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Optima Coil Performance in The Interventional Management of Intracranial Aneurysms Registry

for Intracranial Aneurysm

1 location in Plano

Sponsor: HCA Healthcare Research Institute

Sex: All·Age: 18+

Code: NCT06282939·Recruiting·Listed Feb 2024

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Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in Plano, Dallas +50 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

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Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

Sites in Plano, Round Rock +53 more locations

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting·Listed Nov 2020

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Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR

for Iliac Disease

1 location in Plano

Sponsor: Baylor Research Institute

Sex: All·Age: 18 - 90

Code: NCT05862558·Recruiting·Listed May 2023

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The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment

for Uveitis

1 location in Plano

Sponsor: Texas Retina Associates

Sex: All·Age: 18+

Code: NCT05486468·Phase 3·Recruiting·Listed Aug 2022

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Assessing the Functional Movement Screen as a Reliable Physical Therapy Discharge Criteria for Chronic Lower Back Pain Patients

for Chronic Lower Back Pain

1 location in Plano

Sponsor: Texas Back Institute

Sex: All·Age: 18 - 49

Code: NCT06474429·Recruiting·Listed Jun 2024

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A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

for Nausea and Vomiting

Sites in Plano, San Antonio +8 more locations

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07446439·Phase 3·Recruiting·Listed Mar 2026

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

Sites in Plano, Denton +46 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting·Listed Dec 2025

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

Sites in Plano, McKinney +294 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting·Listed Jun 2025

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

Sites in Plano, McKinney +133 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting·Listed Feb 2024

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Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

for Insomnia Disorder

Sites in Plano, Houston +18 more locations

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 2 - 17

Code: NCT06953869·Phase 3·Recruiting·Listed May 2025

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Product Surveillance Registry

for Cardiac Rhythm Disorders

Sites in Plano, Dallas +127 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting·Listed Feb 2012

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A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

for Systemic Lupus Erythematosus

Sites in Plano, Colleyville +39 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06411249·Phase 4·Recruiting·Listed May 2024

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A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

for Non-obstructive Hypertrophic Cardiomyopathy

Sites in Plano, Houston +20 more locations

Sponsor: Imbria Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07023614·Phase 2·Recruiting·Listed Jun 2025

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A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Plano, Tyler +34 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting·Listed Jul 2024

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Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

for Arrhythmia

Sites in Plano, Dallas +83 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT00271180·Recruiting·Listed Dec 2005

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A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease

for Sjögren

Sites in Plano, Webster +3 more locations

Sponsor: Cullinan Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07041099·Phase 1·Recruiting·Listed Jun 2025

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Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sites in Plano, Austin +26 more locations

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18+

Code: NCT06480383·Phase 2·Recruiting·Listed Jun 2024

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Study of ALTO-300 in MDD

for Major Depressive Disorder

Sites in Plano, Fort Worth +36 more locations

Sponsor: Alto Neuroscience

Sex: All·Age: 18 - 70

Code: NCT05922878·Phase 2·Recruiting·Listed Jun 2023

Apply to this trial