Paid Clinical Trials in San Francisco, CA

As of July 2026, 1,365 paid clinical trials are recruiting in San Francisco, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,100 clinical trials

Closed-Loop Deep Brain Stimulation for Major Depression

for Major Depressive Disorder

1 location in San Francisco

Sponsor: Andrew Krystal

Sex: All·Age: 22 - 70

Code: NCT04004169·Recruiting·Listed Jul 2019

Apply to this trial

IRIS Registry: Intelligent Research in Sight Registry

for Eye Diseases

1 location in San Francisco

Sponsor: American Academy of Ophthalmology

Sex: All·Age: 6 Months+

Code: NCT02485847·Recruiting·Listed Jun 2015

Apply to this trial

Dopamine and Sensorimotor Function in Stuttering

for Stuttering, Adult

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07215884·Phase 1·Recruiting·Listed Oct 2025

Apply to this trial

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for Acute Ischemic Stroke

Sites in San Francisco, Sacramento +49 more locations

Sponsor: Mercy Health Ohio

Sex: All·Age: 18 - 79

Code: NCT05611242·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial

Ropivacaine and Fentanyl for Labor Epidural Initiation

for Pregnancy

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 18+

Code: NCT07076368·Phase 3·Recruiting·Listed Jul 2025

Apply to this trial

Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in San Francisco, Stanford +50 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

Apply to this trial

Patient-centered Information on Permanent Contraception

for Contraception

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 21 - 45·Accepts healthy volunteers

Code: NCT06296797·Recruiting·Listed Mar 2024

Apply to this trial

Direct-to-patient Teledermatology and Computer-assisted Diagnosis

for New Patient Use of Teledermatology Mobile App

Sites in San Francisco +2 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05128006·Recruiting·Listed Nov 2021

Apply to this trial

Volunteers to Investigate Best Results for Ablation and Novel Therapies for Atrial Fibrillation

for Atrial Fibrillation

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT05504356·Recruiting·Listed Aug 2022

Apply to this trial

Pediatric Dose Optimization for Seizures in Emergency Medical Services

for Seizures

Sites in San Francisco, Sacramento +18 more locations

Sponsor: Stanford University

Sex: All·Age: 6 Months - 13

Code: NCT05121324·Phase 3·Recruiting·Listed Nov 2021

Apply to this trial

Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

Sites in San Francisco, Los Angeles +51 more locations

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting·Listed Aug 2021

Apply to this trial

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for Langerhan's Cell Histiocytosis

Sites in San Francisco, Orange +9 more locations

Sponsor: Carl Allen

Sex: All·Age: All ages

Code: NCT04079179·Phase 2·Recruiting·Listed Sep 2019

Apply to this trial

Treating Major Depression With Yoga Mono-therapy

for Depression Mild

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06091527·Recruiting·Listed Oct 2023

Apply to this trial

ChangeGradients: Promoting Adolescent Health Behavior Change

for Alcohol Drinking

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 15 - 17·Accepts healthy volunteers

Code: NCT04110756·Recruiting·Listed Oct 2019

Apply to this trial

Contingency Management for Veteran Smokers Undergoing Major Elective Surgery

for Tobacco Use Disorder

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06678672·Recruiting·Listed Nov 2024

Apply to this trial

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

for Stage IV Esophageal Adenocarcinoma

Sites in San Francisco & Walnut Creek

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT04221893·Recruiting·Listed Jan 2020

Apply to this trial

RCT of Olanzapine for Control of CIV in Children Receiving Highly Emetogenic Chemotherapy

for Vomiting in Infants and/or Children

Sites in San Francisco +4 more locations

Sponsor: The Hospital for Sick Children

Sex: All·Age: 30 Months - 18

Code: NCT03118986·Phase 2·Recruiting·Listed Apr 2017

Apply to this trial

Effect of Magnesium on Neuromonitoring

for Spine

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06975072·Phase 4·Recruiting·Listed May 2025

Apply to this trial

The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

for B-cell Acute Lymphoblastic Leukemia

Sites in San Francisco, Oakland +22 more locations

Sponsor: Pediatric Transplantation & Cellular Therapy Consortium

Sex: All·Age: 1 - 25

Code: NCT03509961·Phase 2·Recruiting·Listed Apr 2018

Apply to this trial

Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population

for Cataract

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT05157113·Phase 4·Recruiting·Listed Dec 2021

Apply to this trial

Mobile App to Help Survivors of Childhood Cancer Navigate Long-Term Follow-Up Care

for Childhood Cancer

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05641961·Recruiting·Listed Dec 2022

Apply to this trial

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

for Sleep Initiation and Maintenance Disorders

Sites in San Francisco, Long Beach +2 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT03642028·Phase 4·Recruiting·Listed Aug 2018

Apply to this trial

Comparison of Methods for Recording Post Operative Pain

for Pain, Postoperative

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06206148·Recruiting·Listed Jan 2024

Apply to this trial

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

Sites in San Francisco, Los Angeles +27 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting·Listed Jul 2022

Apply to this trial

Model-based Electrical Brain Stimulation

for Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring

Sites in San Francisco & Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT05327387·Recruiting·Listed Apr 2022

Apply to this trial

Text Education About Cardiovascular Health and HIV (TEACH-HIV)

for HIV

2 locations in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 40+

Code: NCT05642858·Recruiting·Listed Dec 2022

Apply to this trial

Valacyclovir in Pain Management of Acute Apical Abscesses

for Acute Apical Abscess

Drug: Valacyclovir

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05266040·Phase 2·Recruiting·Listed Mar 2022

Apply to this trial

HEalth Advocate for Liver Transplantation: Improving Transition of Care for Adolescent Liver Transplant Recipients

for Liver Transplant

Sites in San Francisco +1 more location

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 25

Code: NCT06386198·Recruiting·Listed Apr 2024

Apply to this trial

Building Resilience for Surgical Recovery

for Psychosocial Functioning

1 location in San Francisco

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 65+

Code: NCT06174701·Recruiting·Listed Dec 2023

Apply to this trial

Family Mental Health Family Navigator Project (FMHN)

for Mental Health

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 6 - 17·Accepts healthy volunteers

Code: NCT04822636·Recruiting·Listed Mar 2021

Apply to this trial

Emgality for Migraine in Breastmilk

for Migraine

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 18 - 45

Code: NCT06085144·Recruiting·Listed Oct 2023

Apply to this trial

ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer

for Prostate Cancer

Sites in San Francisco, San Diego +2 more locations

Sponsor: University of California, San Diego

Sex: Male·Age: 18+

Code: NCT06579417·Recruiting·Listed Aug 2024

Apply to this trial

CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19

for Long COVID

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT05530317·Recruiting·Listed Sep 2022

Apply to this trial

PRescription Exercise for Older Men With Urinary Disease

for Lower Urinary Tract Symptoms

2 locations in San Francisco

Sponsor: University of California, San Francisco

Sex: Male·Age: 60+

Code: NCT06225479·Recruiting·Listed Jan 2024

Apply to this trial

NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial

for Ischemia Reperfusion Injury

1 location in San Francisco

Sponsor: Kaiser Permanente

Sex: All·Age: 18+

Code: NCT04750616·Phase 2·Recruiting·Listed Feb 2021

Apply to this trial

Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas

for Osteoid Osteoma

Sites in San Francisco, Palo Alto +1 more location

Sponsor: Matthew Bucknor

Sex: All·Age: 8+·Accepts healthy volunteers

Code: NCT02923011·Phase 3·Recruiting·Listed Oct 2016

Apply to this trial

UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones

for Ureteral Stone

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05715086·Recruiting·Listed Feb 2023

Apply to this trial

Topical Treatment for TMJ Arthralgia

for TMJ Pain

1 location in San Francisco

Sponsor: University of the Pacific

Sex: All·Age: 18+

Code: NCT05816226·Phase 3·Recruiting·Listed Apr 2023

Apply to this trial

PrEPsmart 2-1-1 Pilot

for HIV-1-infection

1 location in San Francisco

Sponsor: Public Health Foundation Enterprises, Inc.

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT06631365·Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

Using Electrophysiology to Index Non-invasive Brain Stimulation Effects on Reward System Functioning in Depression

for Major Depressive Disorder

1 location in San Francisco

Sponsor: San Francisco Veterans Affairs Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05194098·Recruiting·Listed Jan 2022

Apply to this trial