Paid Clinical Trials in Santa Monica, CA

As of August 2026, 187 paid clinical trials are recruiting in Santa Monica, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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178 clinical trials

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

for Refractory Metastatic Colorectal Cancer

Sites in Santa Monica, Duarte +4 more locations

Sponsor: Delcath Systems Inc.

Sex: All·Age: 18+

Code: NCT06607458·Phase 2·Recruiting·Listed Sep 2024

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A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

for Solid Tumours

Sites in Santa Monica, Beverly Hills +1 more location

Sponsor: Epkin

Sex: All·Age: 18+

Code: NCT06789172·Phase 1·Recruiting·Listed Jan 2025

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A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Adult Participants With Aggressive B-cell Non-Hodgkin Lymphomas

for B-cell Non-Hodgkins Lymphoma (B-NHL)

Drug: Odronextamab

Sites in Santa Monica, Duarte +7 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05685173·Phase 1·Recruiting·Listed Jan 2023

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Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis

for Low-grade Upper Tract Urothelial Carcinoma

Drug: Nadofaragene Firadenovec

Sites in Santa Monica +8 more locations

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06668493·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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The Effects of a Nutritional Supplement on Sleep Quality

for Sleep

1 location in Santa Monica

Sponsor: Athletic Greens International

Sex: All·Age: 35 - 65·Accepts healthy volunteers

Code: NCT07345260·Recruiting·Listed Jan 2026

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A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment

for Hepatotoxicity

Sites in Santa Monica +5 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT04635111·Recruiting·Listed Nov 2020

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Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors

for Solid Tumor, Adult

Sites in Santa Monica +1 more location

Sponsor: Trethera

Sex: All·Age: 18+

Code: NCT05055609·Phase 1·Recruiting·Listed Sep 2021

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Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors

for Muscle-Invasive Bladder Carcinoma

1 location in Santa Monica

Sponsor: Vasgene Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06493552·Phase 2, Phase 3·Recruiting·Listed Jul 2024

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A Beta-only IL-2 ImmunoTherapY Study

for Advanced Solid Tumor

Sites in Santa Monica, San Diego +3 more locations

Sponsor: Medicenna Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05086692·Phase 1, Phase 2·Recruiting·Listed Oct 2021

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This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects with Any Progressive Locally Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in Santa Monica, Los Angeles +3 more locations

Sponsor: ABL Bio, Inc.

Sex: All·Age: 18+

Code: NCT04762641·Phase 1·Recruiting·Listed Feb 2021

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A Clinical Trial to Assess the Efficacy and Tolerance of a Berberine-based Nutraceutical Formula to Aid Blood Sugar Regulation and Metabolism

for Metabolism Disorder

1 location in Santa Monica

Sponsor: Ultimate International, Inc.

Sex: All·Age: 18 - 70

Code: NCT06700915·Recruiting·Listed Nov 2024

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A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

for Solid Tumors

Sites in Santa Monica, Duarte +6 more locations

Sponsor: Adcentrx Therapeutics

Sex: All·Age: 18+

Code: NCT06710379·Phase 1·Recruiting·Listed Nov 2024

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Urine Metabolites in the Diagnosis of Disease

for Colorectal Cancer

Sites in Santa Monica, Encinitas & Walnut Creek

Sponsor: Luventix, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06710067·Recruiting·Listed Nov 2024

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A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer

for Breast Cancer

1 location in Santa Monica

Sponsor: BriaCell Therapeutics Corporation

Sex: All·Age: 18+

Code: NCT06471673·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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Mobile Vehicle-Based Delivery of Lenacapavir Pre-Exposure Prophylaxis in Los Angeles County

for HIV Prevention

1 location in Santa Monica

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT07467018·Recruiting·Listed Mar 2026

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

Sites in Santa Monica, Los Angeles +777 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023

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ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Santa Monica, Beverly Hills +591 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in Santa Monica, Los Angeles +445 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

Sites in Santa Monica, Los Angeles +427 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

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Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

for Phantom Limb Syndrome With Pain

Sites in Santa Monica, Sacramento +2 more locations

Sponsor: The Ketamine Research Foundation

Sex: All·Age: 18 - 65

Code: NCT07276542·Phase 2, Phase 3·Recruiting·Listed Dec 2025

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A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

for Glioblastoma Multiforme

Sites in Santa Monica, Los Angeles +2 more locations

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT05708352·Phase 2·Recruiting·Listed Feb 2023

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Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

for Sleep Apnea, Obstructive

1 location in Santa Monica

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT00695214·Phase 2·Recruiting·Listed Jun 2008

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Endotypic Traits and Obstructive Sleep Apnea Surgery

for Obstructive Sleep Apnea

Sites in Santa Monica & Westwood, Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 21+

Code: NCT05953610·Phase 2·Recruiting·Listed Jul 2023

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Metastatic Leiomyosarcoma Biomarker Protocol

for Leiomyosarcoma

Sites in Santa Monica +8 more locations

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: All ages

Code: NCT05653388·Recruiting·Listed Dec 2022

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Santa Monica, Los Angeles +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

for Stomach Cancer Stage IV

Drug: Ivonescimab

Sites in Santa Monica +1 more location

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07070466·Phase 2·Recruiting·Listed Jul 2025

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Starting Technology in At Risk Type 1 Diabetes Study

for Diabetes Mellitus, Type 1

Sites in Santa Monica, Torrance & Sylmar

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT06453928·Recruiting·Listed Jun 2024

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Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

for Gout

Sites in Santa Monica +6 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT04875702·Phase 4·Recruiting·Listed May 2021

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Beacon Sensors and Telerehabilitation to Assess and Improve Use of Devices (BeST-AID) for Low Vision

for Low Vision

Sites in Santa Monica, Los Angeles +7 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT06107881·Recruiting·Listed Oct 2023

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SAINT:Trabectedin, Ipilimumab and Nivolumab for Previously Treated Advanced Soft Tissue Sarcoma

for Advanced Soft Tissue Sarcoma

Drug: Ipilimumab

1 location in Santa Monica

Sponsor: Sarcoma Oncology Research Center, LLC

Sex: All·Age: 18+

Code: NCT03138161·Phase 1, Phase 2·Recruiting·Listed May 2017

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Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma

for Sarcoma

Drug: Nivolumab

1 location in Santa Monica

Sponsor: Sarcoma Oncology Research Center, LLC

Sex: All·Age: 18+

Code: NCT03886311·Phase 2·Recruiting·Listed Mar 2019

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Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma

for Leiomyosarcoma

1 location in Santa Monica

Sponsor: Sarcoma Oncology Research Center, LLC

Sex: All·Age: 18+

Code: NCT04535271·Phase 2·Recruiting·Listed Sep 2020

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Pembrolizumab and Pemetrexed for Progressive Chordoma

for Chordomas

1 location in Santa Monica

Sponsor: Saint John's Cancer Institute

Sex: All·Age: 18+

Code: NCT06794645·Phase 2·Recruiting·Listed Jan 2025

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Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy

for Cerebral Palsy

Sites in Santa Monica, Los Angeles +2 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: Up to 18

Code: NCT06189781·Phase 4·Recruiting·Listed Jan 2024

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Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer

for Early-stage Breast Cancer

1 location in Santa Monica

Sponsor: Saint John's Cancer Institute

Sex: All·Age: 18+

Code: NCT04603209·Recruiting·Listed Oct 2020

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CRS Questionnaire Validation Project

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

Sites in Santa Monica +4 more locations

Sponsor: The European Forum for Research and Education in Allergy and Airway Diseases

Sex: All·Age: 18+

Code: NCT06970977·Recruiting·Listed May 2025

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LINNOVATE: Lurbinectedin, Ipilimumab and Nivolumab for Soft Tissue Sarcoma

for Advanced Soft-tissue Sarcoma

Drug: Lurbinectedin

1 location in Santa Monica

Sponsor: ERLINDA M GORDON

Sex: All·Age: 18 - 90

Code: NCT05876715·Phase 1, Phase 2·Recruiting·Listed May 2023

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DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer (epNEC)

Drug: Obrixtamig

Sites in Santa Monica, Duarte +18 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Recruiting·Listed Apr 2026

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Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

Sites in Santa Monica, Los Angeles +22 more locations

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18 - 79

Code: NCT07474792·Phase 2·Recruiting·Listed Mar 2026

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An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for Plaque Psoriasis

Sites in Santa Monica, Los Angeles +16 more locations

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07449702·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial