Paid Clinical Trials in South Carolina

South Carolina has 1,277 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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1,277 clinical trials

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Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

Drug: Tirzepatide

9 locations incl. Jacksonville

Sponsor: T. John Winhusen, PhD

Sex: All·Age: 18+

Code: NCT06651177·Phase 2·Recruiting

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A Trial of TAK-861 for the Treatment of Narcolepsy With Cataplexy

for Narcolepsy Type 1 (NT1)

11 locations incl. Redwood City

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT07363720·Phase 3·Recruiting

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Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

for Hepatitis

Drug: Larsucosterol

48 locations incl. Birmingham

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 18+

Code: NCT07428538·Phase 3·Recruiting

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A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

for Eosinophilic Asthma

20 locations incl. Long Beach

Sponsor: Kymera Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07323654·Phase 2·Recruiting

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A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs

for Prostate Cancer

8 locations incl. Duarte

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07336446·Phase 1, Phase 2·Recruiting

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A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD)

for Graves' Disease

Drug: IMVT-1402

89 locations incl. Phoenix

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07286006·Phase 2·Enrolling By Invitation

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

for Pneumococcal Immunization

13 locations incl. Fayetteville

Sponsor: Sanofi

Sex: All·Age: 42 Days - 89 Days·Accepts healthy volunteers

Code: NCT07348692·Phase 3·Recruiting

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Feasibility of a Technology-Based Intervention for Depression Referral Uptake in Cancer Survivors

for Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07091968·Recruiting

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Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

for Malignant Digestive System Neoplasm

58 locations incl. Fort Smith

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07215624·Recruiting

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Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)

for Heart Failure

4 locations incl. Los Angeles

Sponsor: Echosens

Sex: All·Age: 18+

Code: NCT07222813·Not Yet Recruiting

A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

for Chronic Inducible Urticaria

26 locations incl. Birmingham

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07266402·Phase 3·Recruiting

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Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)

for Paroxysmal AF

22 locations incl. Jonesboro

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 80

Code: NCT07308847·Recruiting

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Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

for Fibromyalgia

16 locations incl. Little Rock

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07398417·Phase 3·Recruiting

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EndoForce Post Approval Study

for End Stage Renal Disease (ESRD)

2 locations incl. Orangeburg

Sponsor: Phraxis, Inc.

Sex: All·Age: 18+

Code: NCT07146854·Recruiting

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TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Drug: Tulmimetostat

8 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07190300·Phase 1, Phase 2·Recruiting

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Solv Multi-Pass Hemodialysis System In-Center Clinical Study

for End Stage Renal Disease

1 location in Greenville

Sponsor: Mozarc Medical US LLC

Sex: All·Age: 18+

Code: NCT07216885·Recruiting

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SUPPORT-T in Patients With Progressive Pulmonary Fibrosis and Their Caregivers

for Progressive Pulmonary Fibrosis

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07269262·Recruiting

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A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

for Pneumococcal Infection

14 locations incl. Madera

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 2 Months - 15 Months·Accepts healthy volunteers

Code: NCT07300267·Phase 1·Recruiting

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A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

for Chronic Idiopathic Constipation (CIC)

Drug: Tenapanor

109 locations incl. Foley

Sponsor: Ardelyx

Sex: All·Age: 18 - 80

Code: NCT07382167·Phase 3·Recruiting

Apply to this trial

Methadone in THA for Post-op Pain and Opioid Reduction

for Post Operative Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT07227064·Phase 3·Recruiting

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Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

for Obesity With Diabetes

Drug: KAI-9531

34 locations incl. Cullman

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07284901·Phase 3·Recruiting

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A Study of Buntanetap in Participants With PD

for Parkinson's Disease (PD)

27 locations incl. Birmingham

Sponsor: Annovis Bio Inc.

Sex: All·Age: 40 - 85

Code: NCT07284784·Phase 2, Phase 3·Recruiting

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ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults

for Asthma

14 locations incl. Birmingham

Sponsor: Enveda Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07301255·Phase 2·Recruiting

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Post-stroke Pain tAN-fMRI

for Post Stroke Pain

2 locations incl. Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 80

Code: NCT07144436·Recruiting

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Methadone in TKA for Post-op Pain and Opioid Reduction

for Post Operative Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT07226076·Phase 3·Recruiting

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A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

for Overweight

34 locations incl. Escondido

Sponsor: Novo Nordisk A/S

Sex: All·Age: 8 - 18

Code: NCT07253285·Phase 3·Recruiting

Apply to this trial

The ArtixASCEND Study

for Acute Lower Limb Arterial Occlusion

14 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT07135895·Recruiting

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A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for Metastatic Non-small Cell Lung Cancer With MTAP Deletion

Drug: Navlimetostat

42 locations incl. Anchorage

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07063745·Phase 2, Phase 3·Recruiting

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Efficacy and Safety of KAI-9531 Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes

for Obesity

Drug: Semaglutide

26 locations incl. Glendale

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07284979·Phase 3·Recruiting

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

15 locations incl. Little Rock

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting

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A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

for Atopic Dermatitis

Drug: Tapinarof

37 locations incl. Birmingham

Sponsor: Organon and Co

Sex: All·Age: 3 Months - 23 Months

Code: NCT07265479·Phase 3·Recruiting

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

117 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting

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A Study to Evaluate Safety, Tolerability and Pharmacokinetics of MNKD-201 in Patients With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

9 locations incl. Fresno

Sponsor: Mannkind Corporation

Sex: All·Age: 40 - 85

Code: NCT07344558·Phase 1·Recruiting

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A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostatic Neoplasms, Castration-Resistant

Drug: Pasritamig

49 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07225946·Phase 3·Recruiting

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Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

for Clear Cell Renal Cell Carcinoma

10 locations incl. Duarte

Sponsor: Neomorph, Inc

Sex: All·Age: 18+

Code: NCT07300241·Phase 1·Recruiting

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Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity

for Obesity and Overweight

35 locations incl. Scottsdale

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07311850·Phase 3·Recruiting

Apply to this trial

Autophagy Maintenance (AUTOMAIN)

for Ovarian Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06971744·Phase 2·Recruiting

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Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

for Obesity

Drug: KAI-9531

23 locations incl. Anniston

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07284875·Phase 3·Recruiting

Apply to this trial

Study of DONQ52 in Active Celiac Disease

for Celiac Disease

Drug: DONQ52

49 locations incl. Anniston

Sponsor: Chugai Pharmaceutical

Sex: All·Age: 18 - 75

Code: NCT07239336·Phase 2·Recruiting

Apply to this trial

Accelerated High-Dose tDCS for Depression

for Major Depression

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 70

Code: NCT07226011·Recruiting

Apply to this trial