Paid Clinical Trials in South Carolina

South Carolina has 1,226 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,109 clinical trials

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for Progressive Pulmonary Fibrosis

Sites in Charleston, Columbia +72 more locations

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT05943535·Phase 3·Recruiting·Listed Jul 2023

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A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor

for Dermatitis Atopic

Drug: Amlitelimab

Sites in Charleston +42 more locations

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT06241118·Phase 3·Recruiting·Listed Feb 2024

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The CONFORM Pivotal Trial

for Atrial Fibrillation

Sites in Columbia, Myrtle Beach +64 more locations

Sponsor: Conformal Medical, Inc

Sex: All·Age: 18+

Code: NCT05147792·Recruiting·Listed Dec 2021

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Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

Drug: Tirzepatide

Sites in Greenville +34 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3·Recruiting·Listed Apr 2025

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A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

for Obstructive Hypertrophic Cardiomyopathy

Drug: Mavacamten

Sites in Greenville +61 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05489705·Recruiting·Listed Aug 2022

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DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

Sites in Spartanburg +32 more locations

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting·Listed Jan 2023

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A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

for Type 2 Diabetes

Drug: Dulaglutide

Sites in Greenville, Columbia +39 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT06739122·Phase 3·Recruiting·Listed Dec 2024

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A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Sites in Charleston +40 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 12+

Code: NCT06338995·Phase 3·Recruiting·Listed Apr 2024

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

for Macular Edema Secondary to Inflammation

Sites in Charleston, West Columbia +51 more locations

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06996080·Phase 3·Recruiting·Listed May 2025

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for Macular Edema Secondary to Inflammation

Sites in Charleston, West Columbia +51 more locations

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06990399·Phase 3·Recruiting·Listed May 2025

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An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

for Colitis, Ulcerative

Sites in Charleston +26 more locations

Sponsor: Pfizer

Sex: All·Age: 18 - 64

Code: NCT06398626·Recruiting·Listed May 2024

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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for Heart Failure

Sites in Charleston +82 more locations

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT06736574·Phase 3·Recruiting·Listed Dec 2024

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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

for Inflammatory Bowel Diseases

Sites in Summerville +24 more locations

Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

Sex: All·Age: 18 - 85

Code: NCT06226883·Phase 2·Recruiting·Listed Jan 2024

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An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

for Oligometastatic Prostate Cancer (OMPC)

Sites in Myrtle Beach, Conway +38 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05939414·Phase 3·Recruiting·Listed Jul 2023

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

for Moderately to Severely Active Ulcerative Colitis

Drug: Afimkibart

Sites in Greenville +69 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06588855·Phase 3·Recruiting·Listed Sep 2024

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A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

for Chronic Obstructive Pulmonary Disease

Sites in Columbia, North Charleston +61 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 40 - 90

Code: NCT05878769·Phase 3·Recruiting·Listed May 2023

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A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

for Eosinophilic Esophagitis (EoE)

Sites in Charleston +28 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 1+

Code: NCT06693531·Recruiting·Listed Nov 2024

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Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

for Amyloidosis

Drug: Acoramidis

Sites in Charleston, Greenville +37 more locations

Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All·Age: 18 - 75

Code: NCT06563895·Phase 3·Recruiting·Listed Aug 2024

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A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

for Parkinsons Disease (PD)

Sites in Charleston +32 more locations

Sponsor: BlueRock Therapeutics

Sex: All·Age: 45 - 75

Code: NCT06944522·Phase 3·Recruiting·Listed Apr 2025

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Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

for Prostate Cancer

Sites in Charleston, Myrtle Beach +31 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT06855277·Phase 3·Recruiting·Listed Mar 2025

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A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

for Psoriasis

Drug: Tirzepatide

Sites in Columbia +39 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06857942·Phase 4·Recruiting·Listed Mar 2025

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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

for Colitis, Ulcerative

Sites in Charleston +17 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 2 - 17

Code: NCT05076175·Phase 2, Phase 3·Recruiting·Listed Oct 2021

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A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

for Myelodysplastic Syndrome

Sites in Charleston +40 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04227847·Phase 1·Recruiting·Listed Jan 2020

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A Study to Assess Growth in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Sites in Columbia +29 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 16

Code: NCT06309979·Recruiting·Listed Mar 2024

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VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

Sites in Charleston +55 more locations

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting·Listed Feb 2024

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A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis

for Primary Biliary Cholangitis (PBC)

Drug: Elafibranor

Sites in Charleston +30 more locations

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT06016842·Phase 3·Recruiting·Listed Aug 2023

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

Sites in Charleston, Columbia +55 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting·Listed Jul 2024

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A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

for Chronic Graft-versus-host-disease

Sites in Charleston, Greenville +33 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06585774·Phase 3·Recruiting·Listed Sep 2024

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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for Treatment Resistant Depression

Sites in Charleston +52 more locations

Sponsor: LivaNova

Sex: All·Age: 18+

Code: NCT03887715·Recruiting·Listed Mar 2019

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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for Hypertension

Sites in Mt. Pleasant +32 more locations

Sponsor: SoniVie Inc.

Sex: All·Age: 22 - 75

Code: NCT06559891·Recruiting·Listed Aug 2024

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

Sites in Charleston +24 more locations

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting·Listed Apr 2025

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Patient Retrospective Outcomes (PRO)

for Chronic Pain

Sites in Greenville +28 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT01550575·Recruiting·Listed Mar 2012

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

Sites in Charleston, Myrtle Beach +32 more locations

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting·Listed May 2025

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Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for Cutaneous Squamous Cell Carcinoma (CSCC)

Drug: Cemiplimab

Sites in Charleston +43 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06585410·Phase 3·Recruiting·Listed Sep 2024

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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: TAK-279

Sites in Greenville +25 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting·Listed Jan 2024

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A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

Drug: Nadofaragene Firadenovec

Sites in Myrtle Beach +38 more locations

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06545955·Phase 3·Recruiting·Listed Aug 2024

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Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

for Persistent Atrial Fibrillation

Sites in Charleston +32 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06735534·Recruiting·Listed Dec 2024

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ELEVATE-HFpEF Clinical Study

for Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Charleston +25 more locations

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 40+

Code: NCT06678841·Recruiting·Listed Nov 2024

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Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

for Relapsing Multiple Sclerosis

Drug: Remibrutinib

Sites in Greenville +39 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 40 - 70

Code: NCT06846281·Phase 3·Recruiting·Listed Feb 2025

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PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

for Heart Failure NYHA Class II

Sites in Charleston, Greenville +43 more locations

Sponsor: Endotronix, Inc.

Sex: All·Age: 18+

Code: NCT05934487·Recruiting·Listed Jul 2023

Apply to this trial