Clinical Trials at Seattle Children's Hospital

As of September 2026, 166 paid clinical trials are recruiting at Seattle Children's Hospital, located at 4800 SAND POINT WAY NE, 818-RC, SEATTLE, WA 98105-3901, phone (206) 987-2000 in Seattle, Washington. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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168 clinical trials at Seattle Children's Hospital

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PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

for High Grade Glioma

Sites in Seattle +12 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 3 - 39

Code: NCT05096481·Phase 2·Recruiting·Listed Oct 2021

Apply to this trial

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

Sites in Seattle +65 more locations

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

Apply to this trial

A-LiNK: Improving Outcomes in Autoimmune Liver Disease

for Autoimmune Hepatitis

Sites in Seattle +7 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05750498·Recruiting·Listed Mar 2023

Apply to this trial

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

Sites in Seattle +30 more locations

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting·Listed Oct 2024

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Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

for Congenital Central Hypoventilation Syndrome

Sites in Seattle +3 more locations

Sponsor: Ilya Khaytin

Sex: All·Age: 3 - 85

Code: NCT03568669·Recruiting·Listed Jun 2018

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Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

for Congenital Disorders of Glycosylation

Sites in Seattle +11 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: All ages

Code: NCT04199000·Recruiting·Listed Dec 2019

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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

for Cystic Fibrosis

Sites in Seattle +34 more locations

Sponsor: Sonya Heltshe

Sex: All·Age: Up to 10

Code: NCT04509050·Recruiting·Listed Aug 2020

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

Sites in Seattle, Spokane +57 more locations

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting·Listed Sep 2022

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Primary Sclerosing Cholangitis in Children

for Primary Sclerosing Cholangitis

Sites in Seattle +8 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 2 - 25

Code: NCT04181138·Recruiting·Listed Nov 2019

Apply to this trial

Resilience Mobile App for Teens and Young Adults With Cancer

for Cancer

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 12 - 25

Code: NCT05842902·Recruiting·Listed May 2023

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NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

for Neuroblastoma

Drug: Irinotecan

Sites in Seattle +12 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 31

Code: NCT06450041·Phase 2·Recruiting·Listed Jun 2024

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

Sites in Seattle +18 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting·Listed Aug 2021

Apply to this trial

Childhood Cancer Survivor Study

for Cancer

Sites in Seattle +26 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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Internet-Delivered Pain Self-Management for Persons With Acute Recurrent and Chronic Pancreatitis Pain

for Pancreatitis

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 18+

Code: NCT06386224·Recruiting·Listed Apr 2024

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Nephrotic Syndrome Study Network

for Minimal Change Disease (MCD)

Sites in Seattle, Spokane +32 more locations

Sponsor: University of Michigan

Sex: All·Age: Up to 80

Code: NCT01209000·Recruiting·Listed Sep 2010

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Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

for High Grade Glioma

Sites in Seattle +9 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 21·Accepts healthy volunteers

Code: NCT06333899·EARLY_Phase 1·Recruiting·Listed Mar 2024

Apply to this trial

A Prospective Database of Infants With Cholestasis

for Biliary Atresia

Sites in Seattle +8 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: Up to 6 Months

Code: NCT00061828·Recruiting·Listed Jun 2003

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Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

for Heart Failure

Sites in Seattle +4 more locations

Sponsor: Stanford University

Sex: All·Age: 0 - 16

Code: NCT06080074·Phase 2·Recruiting·Listed Oct 2023

Apply to this trial

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

for Hematopoietic Stem Cell Transplant (HSCT)

Sites in Seattle +8 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 24

Code: NCT04098445·Recruiting·Listed Sep 2019

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Biliary Atresia Study in Infants and Children

for Biliary Atresia

Sites in Seattle +8 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 6 Months - 20

Code: NCT00345553·Recruiting·Listed Jun 2006

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Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for Lymphoid Leukemia

Sites in Seattle +21 more locations

Sponsor: Stanford University

Sex: All·Age: Up to 26

Code: NCT05865301·Recruiting·Listed May 2023

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Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

for Crohn Disease

Sites in Seattle +20 more locations

Sponsor: Connecticut Children's Medical Center

Sex: All·Age: 6 - 17

Code: NCT05781152·Phase 4·Recruiting·Listed Mar 2023

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Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

Sites in Seattle +21 more locations

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting·Listed Feb 2022

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NEPTUNE Match Study

for Nephrotic Syndrome in Children

Sites in Seattle, Spokane +14 more locations

Sponsor: University of Michigan

Sex: All·Age: 1 - 80

Code: NCT04571658·Recruiting·Listed Oct 2020

Apply to this trial

Study of Individuals Affected With Hypoplasminogenemia

for Plasminogen Deficiency

Sites in Seattle +10 more locations

Sponsor: Indiana Hemophilia &Thrombosis Center, Inc.

Sex: All·Age: All ages

Code: NCT03797495·Recruiting·Listed Jan 2019

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HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)

for Pediatric Hydrocephalus

Sites in Seattle +10 more locations

Sponsor: University of Utah

Sex: All·Age: Up to 18

Code: NCT00670735·Recruiting·Listed May 2008

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Seattle, Spokane +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

Apply to this trial

ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

for Adamantinomatous Craniopharyngioma

Sites in Seattle +6 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 39

Code: NCT05233397·Phase 2·Recruiting·Listed Feb 2022

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Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

Sites in Seattle +10 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting·Listed May 2023

Apply to this trial

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

for Pediatric Intestinal Failure

Sites in Seattle +10 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 6 Months - 25

Code: NCT04629014·Recruiting·Listed Nov 2020

Apply to this trial

The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies

for Gastrointestinal Complication

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 0 Days - 55

Code: NCT06072976·Recruiting·Listed Oct 2023

Apply to this trial

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

for Inflammatory Bowel Diseases

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 6 - 21

Code: NCT06315179·Recruiting·Listed Mar 2024

Apply to this trial

Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

for Failed or Difficult Intubation, Sequela

Sites in Seattle +50 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02493478·Recruiting·Listed Jul 2015

Apply to this trial

Neuroblastoma Biology Study

for Neuroblastoma

Sites in Seattle +13 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting·Listed Apr 2012

Apply to this trial

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for High Grade Glioma

Sites in Seattle +8 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04655404·EARLY_Phase 1·Recruiting·Listed Dec 2020

Apply to this trial

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

for Central Nervous System Tumor

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 1 - 26

Code: NCT04185038·Phase 1·Recruiting·Listed Dec 2019

Apply to this trial

The INFLUENTIAL Trial- Evaluation of National Inpatient Influenza Vaccination Program

for Influenza

Sites in Seattle +1 more location

Sponsor: University of Colorado, Denver

Sex: All·Age: 6 Months - 99·Accepts healthy volunteers

Code: NCT05832307·Recruiting·Listed Apr 2023

Apply to this trial

Integrated Suicide Supports and Safety Planning for Youth

for Suicidal Ideation

1 location in Seattle

Sponsor: University of Washington

Sex: All·Age: 13 - 21

Code: NCT06701006·Recruiting·Listed Nov 2024

Apply to this trial

The Myelin Disorders Biorepository Project

for Leukodystrophy

Sites in Seattle +22 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting·Listed Feb 2017

Apply to this trial

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Seattle, Spokane +66 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

Apply to this trial