Paid Clinical Trials in Spartanburg, SC

As of June 2026, 100 paid clinical trials are recruiting in Spartanburg, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 26, 2026.

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101 clinical trials

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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

72 locations incl. Decatur

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting

Apply to this trial

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

464 locations incl. Fairbanks

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting

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Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

for Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Drug: Durvalumab

8 locations incl. Los Alamitos

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT06501625·Phase 1, Phase 2·Recruiting

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Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

for Resectable Lung Non-Small Cell Carcinoma

378 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632327·Phase 3·Recruiting

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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

76 locations incl. Anniston

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06628908·Phase 3·Recruiting

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A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

29 locations incl. Birmingham

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 18 - 80

Code: NCT06559150·Phase 2·Recruiting

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RevCore for In Stent Thrombosis

for In-stent Thrombosis

16 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06394739·Recruiting

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A Study to Evaluate Solrikitug in Participants With COPD (ZION)

for COPD

101 locations incl. Birmingham

Sponsor: Uniquity One (UNI)

Sex: All·Age: 40 - 75

Code: NCT06496620·Phase 2·Recruiting

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Global Paradise System US Post Approval Study

for Hypertension

39 locations incl. Sacramento

Sponsor: ReCor Medical, Inc.

Sex: All·Age: 18+

Code: NCT06297291·Recruiting

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The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

for Peripheral Arterial Disease

20 locations incl. Scottsdale

Sponsor: Avantec Vascular

Sex: All·Age: 18+

Code: NCT06321575·Recruiting

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A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

for Atopic Dermatitis

Drug: Upadacitinib

83 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18 - 63

Code: NCT06389136·Phase 3·Recruiting

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EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

for Breast Cancer

53 locations incl. Anchorage

Sponsor: Exact Sciences Corporation

Sex: All·Age: 18+

Code: NCT06401421·Recruiting

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IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for Advanced Melanoma

Drug: Nivolumab

37 locations incl. Tucson

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT06112314·Phase 3·Recruiting

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Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

for Breast Cancer

673 locations incl. Anchorage

Sponsor: NRG Oncology

Sex: All·Age: 18 - 100

Code: NCT05896189·Recruiting

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

235 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

491 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting

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SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

for Chronic Kidney Diseases

28 locations incl. Bullhead City

Sponsor: VenoStent

Sex: All·Age: 18+

Code: NCT06001827·Recruiting

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Vitamin D for Prostate Endocrine Therapy

for Stage I Prostate Cancer AJCC v8

51 locations incl. Newark

Sponsor: University of Rochester

Sex: Male·Age: 50+

Code: NCT05838716·Phase 3·Recruiting

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

402 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting

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LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for Advanced Colorectal Carcinoma

225 locations incl. Fort Smith

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06073431·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1208 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

for Hodgkin Lymphoma

428 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06002828·Recruiting

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A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

for Alopecia Areata

Drug: Upadacitinib

77 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 12 - 63

Code: NCT06012240·Phase 3·Recruiting

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An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

148 locations incl. Dothan

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05952557·Phase 3·Recruiting

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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

186 locations incl. Alexander City

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting

Apply to this trial

Mindfulness Intervention for College Students With ADHD

for Attention Deficit Hyperactivity Disorder

2 locations incl. Tuscaloosa

Sponsor: University of Alabama, Tuscaloosa

Sex: All·Age: 17 - 25

Code: NCT06076967·Recruiting

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A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension

for Knee Osteoarthritis

7 locations incl. Fayetteville

Sponsor: Canary Medical

Sex: All·Age: 18+

Code: NCT06040827·Recruiting

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A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: PF-07275315

52 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05995964·Phase 2·Recruiting

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Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

476 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting

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Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for Malignant Solid Neoplasm

36 locations incl. Fairfield

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642611·Phase 3·Recruiting

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A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

127 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05774951·Phase 3·Recruiting

Apply to this trial

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

48 locations incl. Scottsdale

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting

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Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for Advanced Melanoma

Drug: Tebentafusp

25 locations incl. Phoenix

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT05549297·Phase 3·Recruiting

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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

184 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting

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Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

for Atherosclerotic Cardiovascular Disease in Patients With ESKD

Drug: Clazakizumab

164 locations incl. Decatur

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT05485961·Phase 2, Phase 3·Recruiting

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

42 locations incl. Phoenix

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

746 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

1021 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting

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A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB

for FSGS

54 locations incl. Birmingham

Sponsor: Dimerix Bioscience Pty Ltd

Sex: All·Age: 12 - 80

Code: NCT05183646·Phase 3·Recruiting

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Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease

for Proteinuric Kidney Disease

227 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 10 - 65

Code: NCT05312879·Phase 2, Phase 3·Recruiting

Apply to this trial