Oncology Clinical Trials in Tampa, FL

As of September 2026, 246 paid clinical trials are recruiting for Oncology in Tampa, Florida. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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250 clinical trials for Oncology

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A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

for Unresectable Melanoma

Drug: IOV-4001

Sites in Tampa, Orlando +8 more locations

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05361174·Phase 1, Phase 2·Recruiting·Listed May 2022

Apply to this trial

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for Solid Tumor, Adult

Sites in Tampa +18 more locations

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06625775·Phase 1·Recruiting·Listed Oct 2024

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Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for Solid Tumor, Adult

Sites in Tampa, Jacksonville +11 more locations

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT04981119·Recruiting·Listed Jul 2021

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Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

for Cholangiocarcinoma

Drug: Trametinib

Sites in Tampa, Orlando +6 more locations

Sponsor: Genfit

Sex: All·Age: 18+

Code: NCT05874414·Phase 1, Phase 2·Recruiting·Listed May 2023

Apply to this trial

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

for Non-Small Cell Lung Cancer

Sites in Tampa +15 more locations

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06917079·Phase 1·Recruiting·Listed Apr 2025

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Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

for Non-small Cell Lung Cancer (NSCLC)

Sites in Tampa +20 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT05379985·Phase 1, Phase 2·Recruiting·Listed May 2022

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A Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung Cancer

for NSCLC

Sites in Tampa +1 more location

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04077099·Phase 1, Phase 2·Recruiting·Listed Sep 2019

Apply to this trial

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

for Solid Tumor

Sites in Tampa +4 more locations

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT04300556·Phase 1, Phase 2·Recruiting·Listed Mar 2020

Apply to this trial

QTX3034 in Patients With KRAS G12D Mutation

for Solid Tumors

Sites in Tampa, Sarasota +12 more locations

Sponsor: Quanta Therapeutics

Sex: All·Age: 18+

Code: NCT06227377·Phase 1·Recruiting·Listed Jan 2024

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Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Tampa +10 more locations

Sponsor: Pyxis Oncology, Inc

Sex: All·Age: 18+

Code: NCT06795412·Phase 1, Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for Oncology

Sites in Tampa +12 more locations

Sponsor: Nested Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06326411·Phase 1·Recruiting·Listed Mar 2024

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A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

for Hepatocellular Carcinoma

Sites in Tampa +17 more locations

Sponsor: Tvardi Therapeutics, Incorporated

Sex: All·Age: 18+

Code: NCT05440708·Phase 1, Phase 2·Recruiting·Listed Jul 2022

Apply to this trial

Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Linvoseltamab

Sites in Tampa +6 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT03761108·Phase 1, Phase 2·Recruiting·Listed Dec 2018

Apply to this trial

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

for Hepatocellular Carcinoma

Sites in Tampa, Miami +10 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: 18+

Code: NCT05733598·Phase 2·Recruiting·Listed Feb 2023

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A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Tampa, Orlando +11 more locations

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05932862·Phase 1·Recruiting·Listed Jul 2023

Apply to this trial

A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

for AML

Sites in Tampa, Hollywood +19 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05473910·Phase 1·Recruiting·Listed Jul 2022

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Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for Non-Hodgkin Lymphoma

Sites in Tampa +9 more locations

Sponsor: Imugene Limited

Sex: All·Age: 18+

Code: NCT03666000·Phase 1·Recruiting·Listed Sep 2018

Apply to this trial

A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

for Breast Cancer

Sites in Tampa, Miami +11 more locations

Sponsor: Processa Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06568692·Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

Sites in Tampa +14 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting·Listed Jun 2020

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AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

for B-cell Malignancy

Sites in Tampa, Miami Beach +11 more locations

Sponsor: Carna Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05602363·Phase 1·Recruiting·Listed Nov 2022

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A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

for Endometrial Cancer

Drug: Lifileucel

Sites in Tampa, Orlando +10 more locations

Sponsor: Iovance Biotherapeutics, Inc.

Sex: Female·Age: 18 - 70

Code: NCT06481592·Phase 2·Recruiting·Listed Jul 2024

Apply to this trial

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for Solid Tumors

Sites in Tampa, Jacksonville +15 more locations

Sponsor: ORIC Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05315700·Phase 1, Phase 2·Recruiting·Listed Apr 2022

Apply to this trial

Study of AVZO-021 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Tampa, Sarasota +9 more locations

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05867251·Phase 1, Phase 2·Recruiting·Listed May 2023

Apply to this trial

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

for Solid Tumor, Adult

Sites in Tampa, Jacksonville +8 more locations

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT06682793·Phase 1, Phase 2·Recruiting·Listed Nov 2024

Apply to this trial

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

for Leukemia

Sites in Tampa, Miami +11 more locations

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06501196·Phase 1·Recruiting·Listed Jul 2024

Apply to this trial

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

Sites in Tampa, Gainesville +20 more locations

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting·Listed May 2023

Apply to this trial

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

for Colorectal Cancer

Sites in Tampa +9 more locations

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07659795·Phase 2·Recruiting·Listed Jun 2026

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Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

for Pancreatic Cancer

Sites in Tampa +5 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT07621718·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

for Advanced Solid Tumor

Sites in Tampa, Sarasota +1 more location

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT07629960·Phase 1, Phase 2·Recruiting·Listed Jun 2026

Apply to this trial

Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)

for Small Cell Lung Cancer

Drug: Tarlatamab

Sites in Tampa +6 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07531095·Phase 1·Recruiting·Listed Apr 2026

Apply to this trial

Artidis Nanomechanical Signature Profiling of Pancreatic Cancer Specimens

for Pancreatic Cancer

1 location in Tampa

Sponsor: ARTIDIS AG

Sex: All·Age: 18+

Code: NCT07542041·Recruiting·Listed Apr 2026

Apply to this trial

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

for Glioblastoma Multiforme of Brain

Sites in Tampa +2 more locations

Sponsor: Tetragon Biosciences Ltd

Sex: All·Age: 18+

Code: NCT07464925·Phase 1·Recruiting·Listed Mar 2026

Apply to this trial

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

for Multiple Myeloma

Drug: ABBV-438

Sites in Tampa +5 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07409246·Phase 1·Recruiting·Listed Feb 2026

Apply to this trial

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

for PIK3CA Mutations

Sites in Tampa +10 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07383506·Phase 1·Recruiting·Listed Feb 2026

Apply to this trial

FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer

for Breast Cancer

Sites in Tampa +6 more locations

Sponsor: Regor Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT05304962·Phase 1·Recruiting·Listed Mar 2022

Apply to this trial

Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

for Leukemia, Myeloid, Acute

Sites in Tampa +5 more locations

Sponsor: Orca Biosystems, Inc.

Sex: All·Age: 18+

Code: NCT07216443·Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Sites in Tampa +10 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT07111520·Phase 1, Phase 2·Recruiting·Listed Aug 2025

Apply to this trial

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

for Brain Tumor

Sites in Tampa, Fort Lauderdale +6 more locations

Sponsor: InSightec

Sex: All·Age: 18 - 100

Code: NCT05317858·Phase 3·Recruiting·Listed Apr 2022

Apply to this trial

Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy

for Bladder Cancer

Sites in Tampa +2 more locations

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT07144319·Recruiting·Listed Aug 2025

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A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Sites in Tampa +6 more locations

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06969430·Phase 1, Phase 2·Recruiting·Listed May 2025

Apply to this trial

Conditions in Oncology (Tampa, FL)

Non-small cell lung cancer (NSCLC)· 36 Solid tumor· 33 Breast cancer· 28 Cancer (any)· 20 Colorectal cancer· 19 Pancreatic cancer· 18 Acute myeloid leukemia (AML)· 18 Myelodysplastic syndromes (MDS)· 17 Ovarian cancer· 13 Melanoma· 13 Endometrial cancer· 11 Multiple myeloma· 10 Metastatic breast cancer· 9 Prostate cancer· 9 Head and neck cancer· 9 Triple-negative breast cancer· 8 Metastatic prostate cancer· 8 Non-Hodgkin lymphoma· 8 Hematologic malignancy· 8 Bladder cancer· 7 Leukemia (other)· 7 Small cell lung cancer· 6 Liver cancer· 6 Acute lymphoblastic leukemia· 6 Diffuse large B-cell lymphoma (DLBCL)· 6 Osteosarcoma· 6 Biliary tract cancer· 5 Chronic lymphocytic leukemia (CLL)· 5 Follicular lymphoma· 5 Mantle cell lymphoma· 5 HER2-negative breast cancer· 4 Lung cancer· 4 Esophageal cancer· 4 Fallopian tube cancer· 4 Glioma· 4 Myelofibrosis· 4 Marginal zone lymphoma· 4 Sarcoma· 4 HER2-positive breast cancer· 3 Metastatic colorectal cancer· 3 Colon cancer· 3 Rectal cancer· 3 Gastric cancer· 3 Kidney cancer· 3 Glioblastoma· 3 Brain cancer· 3 Myeloproliferative neoplasm· 3 Small lymphocytic lymphoma· 3 Ewing sarcoma· 3 Neuroblastoma· 3 Mesothelioma· 3 Gastroesophageal junction cancer· 2 Gastrointestinal cancer· 2 Skin cancer· 2 Thyroid cancer· 2 Pediatric cancer· 2 Neuroendocrine tumors· 2 Chronic myelomonocytic leukemia· 1 Soft tissue sarcoma· 1 Rhabdomyosarcoma· 1