Clinical Trials at Moffitt Cancer Center

As of July 2026, 293 paid clinical trials are recruiting at Moffitt Cancer Center, located at 12902 USF MAGNOLIA DR, TAMPA, FL 33612-9416, phone (813) 745-3862 in Tampa, Florida. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 1, 2026.

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293 clinical trials at Moffitt Cancer Center

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

Apply to this trial

Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

for Pancreatic Cancer

3 locations incl. Lakewood Rch

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT04275557·Recruiting

Apply to this trial

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

for Malignant Peripheral Nerve Sheath Tumors

9 locations incl. Tampa

Sponsor: Washington University School of Medicine

Sex: All·Age: All ages

Code: NCT03141021·Recruiting

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Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for Locally Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

9 locations incl. Sacramento

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07012031·Phase 1, Phase 2·Recruiting

Apply to this trial

Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors

for Smoking Cessation

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07447635·Recruiting

Apply to this trial

Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC

for Metastatic Castration-resistant Prostate Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Male·Age: 18+

Code: NCT07476001·Phase 2·Recruiting

Apply to this trial

Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALL

for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT07250087·Phase 1·Recruiting

Apply to this trial

Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Tebentafusp

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT07276386·Phase 2·Recruiting

Apply to this trial

Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma

for Melanoma

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06961357·Phase 1, Phase 2·Recruiting

Apply to this trial

Hybrid Effectiveness-Implementation Trial to Integrate Precision Skin Cancer Risk Feedback in FQHCs

for Skin Cancer

2 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07222995·Recruiting

Apply to this trial

A First-in-Human Study of FID-022 in Solid Tumor Patients

for Pancreatic Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT07249775·Recruiting

Apply to this trial

ILR to Prevent BRCL_MCC 23608

for Breast Cancer Lymphedema

3 locations incl. Tampa

Sponsor: University of South Florida

Sex: Female·Age: 18 - 75

Code: NCT07127003·Recruiting

Apply to this trial

Ropeginterferon in Patients w/Cutaneous T-Cell Lymphoma (CTCL)

for Cutaneous T Cell Lymphoma

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT07047885·Phase 1·Recruiting

Apply to this trial

Axatilimab for Sclerotic Chronic Graft-versus-Host Disease

for Chronic Graft Versus Host Disease

3 locations incl. Tampa

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07011810·Phase 2·Recruiting

Apply to this trial

Predictors of Health-Related QOL in Adults With CLL or Small Lymphocytic Lymphoma

for Small Lymphocytic Lymphoma (SLL)

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT07030400·Recruiting

Apply to this trial

The MIND-BC Study: MIND Diet for Breast Cancer Cognition

for Breast Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Female·Age: 18+

Code: NCT07018986·Recruiting

Apply to this trial

Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes

for Cancer

3 locations incl. Tampa

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT07061652·Recruiting

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Study of NALIRIFOX in Advanced Unresectable Small Bowel Tumors

for Small Bowel Adenocarcinoma

7 locations incl. Tampa

Sponsor: Tiago Biachi de Castria

Sex: All·Age: 18+

Code: NCT06835387·Phase 2·Recruiting

Apply to this trial

Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma

for Cutaneous Sarcoma

3 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT07007273·Phase 2·Recruiting

Apply to this trial

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

for Non-small Cell Lung Cancer

5 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06745882·Phase 2·Recruiting

Apply to this trial

Elranatamab Post Cilta-cel in Patients With Clinical High Risk Relapsed Myeloma

for Myeloma

Drug: Elranatamab

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06947083·Phase 2·Recruiting

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Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

for Metastatic Colorectal Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06553885·Phase 2·Recruiting

Apply to this trial

Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.

for Graft Vs Host Disease

3 locations incl. Tampa

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT06450925·Phase 2·Recruiting

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Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell Lym

for Large B-cell Lymphoma

Drug: Tafasitamab

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06760156·Phase 2·Recruiting

Apply to this trial

A Trial of Durvalumab (MEDI4736) Plus Monalizumab in Non-Muscle-Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer

Drug: Monalizumab

4 locations incl. Tampa

Sponsor: John Sfakianos

Sex: All·Age: 18+

Code: NCT06503614·Phase 2·Recruiting

Apply to this trial

Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer

for Breast Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06833502·Phase 2·Recruiting

Apply to this trial

BMT-CARE: Psychosocial Intervention for Transplant Caregivers

for Bone Marrow Transplant Complications

3 locations incl. Birmingham

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06472089·Recruiting

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Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

for Chronic Graft-versus-host Disease (cGVHD)

Drug: Ruxolitinib

5 locations incl. Miami

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06660355·Phase 2·Recruiting

Apply to this trial

Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases

for Breast Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06238921·Phase 1, Phase 2·Recruiting

Apply to this trial

Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors

for Hematopoietic Stem Cell Transplant

3 locations incl. Tampa

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06328127·Recruiting

Apply to this trial

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

10 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting

Apply to this trial

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

2 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18 - 80

Code: NCT06660368·Phase 2·Recruiting

Apply to this trial

Discontinuation of Hypomethylating Agent and Venetoclax in Patients With AML MRD

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06511882·Phase 2·Recruiting

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Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Aflibercept

4 locations incl. Los Angeles

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06121180·Phase 2·Recruiting

Apply to this trial

Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer

for Breast Cancer Metastatic Breast Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06691035·Phase 1·Recruiting

Apply to this trial

Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC

for Metastatic Castration-resistant Prostate Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Male·Age: 18+

Code: NCT06193486·Phase 1·Recruiting

Apply to this trial

Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening

for Colorectal Cancer Screening

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT06745895·Recruiting

Apply to this trial

A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

for Head and Neck Squamous Cell Carcinoma

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06597565·Phase 2·Recruiting

Apply to this trial

Working Through Outreach, Navigation and Digital Enabled Referral and Recruitment Strategies (ACT WONDER²S)

for Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06560398·Recruiting

Apply to this trial

Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R MCL

for Mantle Cell Lymphoma

3 locations incl. Stanford

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06553872·Phase 2·Recruiting

Apply to this trial