Paid Clinical Trials in Tennessee

Tennessee has 2,062 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,839 clinical trials

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A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

for Breast Cancer

Sites in Nashville +4 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06695845·Phase 2·Recruiting·Listed Nov 2024

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

Sites in Memphis +20 more locations

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting·Listed Sep 2023

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Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Nashville +16 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT06800313·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

for Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations

Sites in Nashville +14 more locations

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05967689·Phase 2·Recruiting·Listed Aug 2023

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Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

for HER2 Expressing Solid Tumors

Sites in Nashville +10 more locations

Sponsor: Vironexis Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT07192432·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Drug: Osimertinib

Sites in Nashville, Knoxville +13 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07155187·Phase 2, Phase 3·Recruiting·Listed Sep 2025

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A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

for Locally Advanced Breast Cancer

Sites in Nashville +26 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06827236·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

for Relapsed or Refractory Multiple Myeloma

Sites in Nashville +9 more locations

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18+

Code: NCT07116616·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for Colorectal Cancer

Sites in Nashville +21 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07023289·Phase 2·Recruiting·Listed Jun 2025

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Total Shoulder Arthroplasty Multi-Center Registry

for Shoulder Arthroplasty

Sites in Germantown +15 more locations

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 100

Code: NCT03511586·Recruiting·Listed Apr 2018

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A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-Resistant Prostate Cancer

Sites in Nashville +22 more locations

Sponsor: Kyntra Bio

Sex: Male·Age: 18+

Code: NCT06842498·Phase 2·Recruiting·Listed Feb 2025

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Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

for Breast Reconstruction

Sites in Chattanooga, Johnson City +15 more locations

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06575192·Phase 3·Recruiting·Listed Aug 2024

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The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

for Hemorrhagic Stroke

Sites in Nashville +23 more locations

Sponsor: phenox Inc.

Sex: All·Age: 18+

Code: NCT07143019·Recruiting·Listed Aug 2025

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Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

for Ewing Sarcoma

Sites in Nashville +18 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 12 - 85

Code: NCT03715933·Phase 1·Recruiting·Listed Oct 2018

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Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies

for Advanced Solid Malignancies

Sites in Nashville +10 more locations

Sponsor: Georgiamune Inc

Sex: All·Age: 18+

Code: NCT06028074·Phase 1, Phase 2·Recruiting·Listed Sep 2023

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A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

for Multiple Sclerosis (MS) Primary Progressive

Sites in Cordova +15 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07067463·Phase 3·Recruiting·Listed Jul 2025

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A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in Nashville +11 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06172478·Phase 2·Recruiting·Listed Dec 2023

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A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for Geographic Atrophy

Sites in Nashville +14 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 50+

Code: NCT05626114·Phase 2·Recruiting·Listed Nov 2022

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A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

for Primary Membranous Nephropathy

Sites in Nashville, Knoxville +13 more locations

Sponsor: Biogen

Sex: All·Age: 18 - 80

Code: NCT06962800·Phase 3·Recruiting·Listed May 2025

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A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for Colorectal Neoplasms

Sites in Nashville +20 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT06131840·Phase 1·Recruiting·Listed Nov 2023

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CoMind Early Feasibility Study

for Intracranial Pressure

Sites in Nashville +11 more locations

Sponsor: CoMind Technologies Limited

Sex: All·Age: 18+

Code: NCT06368648·Recruiting·Listed Apr 2024

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REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome

for Angelman Syndrome

Sites in Nashville +17 more locations

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 50

Code: NCT06914609·Phase 3·Recruiting·Listed Apr 2025

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Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

for Generalized Myasthenia Gravis

Sites in Chattanooga +18 more locations

Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Sex: All·Age: 18+

Code: NCT06463587·Phase 3·Recruiting·Listed Jun 2024

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The ArtixASCEND Study

for Acute Lower Limb Arterial Occlusion

Sites in Nashville +19 more locations

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT07135895·Recruiting·Listed Aug 2025

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A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for Advanced Solid Tumors

Sites in Nashville +8 more locations

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06760819·Phase 2·Recruiting·Listed Jan 2025

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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

for Heart Failure

Sites in Memphis +19 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 29 Days - 17

Code: NCT05714085·Phase 2, Phase 3·Recruiting·Listed Feb 2023

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A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

for Prostatic Neoplasms

Sites in Nashville +11 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT06095089·Phase 1·Recruiting·Listed Oct 2023

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A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

for Autoimmune Haemolytic Anaemia

Sites in Memphis +22 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07086976·Phase 3·Recruiting·Listed Jul 2025

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Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

for Complex Cardiovascular Surgery With Cardiopulmonary Bypass

Sites in Nashville +15 more locations

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT07094087·Phase 3·Recruiting·Listed Jul 2025

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A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

for Solid Tumor

Sites in Nashville +10 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06619587·Phase 1·Recruiting·Listed Oct 2024

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AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

for KRAS Altered Advanced or Metastatic Solid Tumors

Sites in Nashville +9 more locations

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07094113·Phase 1·Recruiting·Listed Jul 2025

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A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

for Head and Neck Squamous Cell Carcinoma (HNSCC)

Drug: Cemiplimab

Sites in Nashville, Knoxville +16 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06769698·Phase 2·Recruiting·Listed Jan 2025

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A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

for Solid Tumors

Drug: INCB161734

Sites in Nashville +12 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06179160·Phase 1·Recruiting·Listed Dec 2023

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A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Nashville +16 more locations

Sponsor: K36 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05651932·Phase 1·Recruiting·Listed Dec 2022

Apply to this trial

Investigations of Reproductive Cancers in Women

for Uterine Cancer

Sites in Nashville, Memphis +11 more locations

Sponsor: PinkDx, Inc.

Sex: Female·Age: 45 - 100

Code: NCT06527157·Recruiting·Listed Jul 2024

Apply to this trial

The Ailliance Post-Market Clinical Study

for Spinal Deformity

Sites in Nashville +21 more locations

Sponsor: Medtronic Spinal and Biologics

Sex: All·Age: 18+

Code: NCT05856370·Recruiting·Listed May 2023

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A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

for Lymphoma

Sites in Nashville +13 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT07015242·Phase 2·Recruiting·Listed Jun 2025

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A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

for Prostate Cancer

Sites in Nashville +11 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT07005154·Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

Sites in Nashville, Memphis +15 more locations

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting·Listed Jan 2026

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Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

for Non-Small Cell Lung Cancer (NSCLC)

Drug: daraxonrasib

Sites in Nashville +19 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06128551·Phase 1, Phase 2·Recruiting·Listed Nov 2023

Apply to this trial