Paid Clinical Trials in Tennessee

Tennessee has 2,157 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,157 clinical trials

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Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

for Psoriatic Arthritis

16 locations incl. Huntington Beach

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06865105·Phase 2·Recruiting

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A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for Lymphoma, Large B-Cell, Diffuse

Drug: Polatuzumab Vedotin

70 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06890884·Phase 2·Recruiting

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A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for Breast Cancer

51 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06790693·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

for Ovarian Cancer

30 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT06824467·Phase 3·Recruiting

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Brief Interventions to Improve Behavior Outcomes and Prevent Cavities

for Parenting

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 9 Months - 3·Accepts healthy volunteers

Code: NCT06588725·Enrolling By Invitation

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

for ALS

10 locations incl. La Jolla

Sponsor: Amylyx Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06665165·Phase 1·Recruiting

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CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)

for AML

4 locations incl. Sacramento

Sponsor: CERo Therapeutics Holdings, Inc.

Sex: All·Age: 18 - 85

Code: NCT06834282·Phase 1·Recruiting

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Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age

for Hyperkalemia

Drug: patiromer

13 locations incl. Aurora

Sponsor: Vifor Pharma, Inc.

Sex: All·Age: 0 - 11

Code: NCT05766839·Phase 2·Recruiting

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FORWARD CAD IDE Study

for Coronary Arterial Disease (CAD)

28 locations incl. La Jolla

Sponsor: Shockwave Medical, Inc.

Sex: All·Age: 18+

Code: NCT06662500·Recruiting

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Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

for Advanced HR+/HER2- Breast Cancer

8 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06726148·Phase 1, Phase 2·Recruiting

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A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for Graft-versus-host Disease (GVHD)

Drug: Ruxolitinib

30 locations incl. Palo Alto

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06615050·Phase 3·Recruiting

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Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

for Lung Non-Small Cell Carcinoma

243 locations incl. Jonesboro

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06498635·Phase 3·Recruiting

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Evaluating rhPDGF-BB-Enhanced Wound Matrix for Head and Neck Reconstruction

for Wound Healing

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 22+

Code: NCT06634030·Phase 2·Recruiting

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A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

for Metastatic Solid Tumor

20 locations incl. Tucson

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06657144·Phase 1·Recruiting

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School Readiness Intervention for Preschool Children With Sickle Cell Disease

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 42 Months - 78 Months

Code: NCT06367192·Recruiting

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CT-95 in Advanced Cancers Associated With Mesothelin Expression

for Mesothelin-Expressing Tumors

9 locations incl. Denver

Sponsor: Context Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06756035·Phase 1·Recruiting

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A Study of PHST001 in Advanced Solid Tumors

for Advanced Solid Tumors

20 locations incl. Beverly Hills

Sponsor: Pheast Therapeutics

Sex: All·Age: 18+

Code: NCT06840886·Phase 1·Recruiting

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Pain with Differing Intraperitoneal Washes At the End of Laparoscopic Gynecologic Surgery

for Laparoscopic Adnexal Surgery

1 location in Memphis

Sponsor: University of Tennessee

Sex: Female·Age: 18+

Code: NCT06842771·Phase 4·Not Yet Recruiting

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

for Non-Small Cell Lung Cancer

16 locations incl. Los Angeles

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06917079·Phase 1·Recruiting

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The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

18 locations incl. Torrance

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting

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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

for Ulcerative Colitis

100 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 80

Code: NCT06581328·Phase 4·Recruiting

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A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)

for Esophageal Squamous Cell Carcinoma

6 locations incl. Fullerton

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644781·Phase 3·Recruiting

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting

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A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

for Elevated Blood Pressure

5 locations incl. Valley Village

Sponsor: Zona Health, Inc

Sex: All·Age: 22+

Code: NCT06843577·Recruiting

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Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

85 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06890598·Phase 3·Recruiting

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Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer

for Lung Cancer - Non Small Cell Squamous

Drug: Petosemtamab

6 locations incl. St. Petersburg

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT07353957·Phase 2·Recruiting

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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

55 locations incl. Bakersfield

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting

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A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors

for Advanced Malignant Tumors

4 locations incl. Hackensack

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06764771·Phase 1·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for Chronic Obstructive Pulmonary Disease (COPD)

68 locations incl. Cullman

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06878261·Phase 3·Recruiting

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Whole Foods for Teens: A Pilot Dietary Intervention to Reduce Body Adiposity in Adolescents With Obesity

for Obesity, Childhood

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 10+

Code: NCT06464497·Recruiting

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A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors

for Triple Negative Locally Advanced Non-resectable Breast Cancer

6 locations incl. Los Angeles

Sponsor: Marengo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06827613·Phase 1, Phase 2·Recruiting

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Gene Editing For Sickle Cell Disease

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18 - 24

Code: NCT06506461·Phase 1·Recruiting

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

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First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

for Advanced Solid Tumors

5 locations incl. Sarasota

Sponsor: Accent Therapeutics

Sex: All·Age: 18+

Code: NCT06799065·Phase 1·Recruiting

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MObile Support Adapted to Individual Contexts

for Type 2 Diabetes

2 locations incl. Birmingham

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 75

Code: NCT06828549·Enrolling By Invitation

Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults

for RSV Infection

5 locations incl. Phoenix

Sponsor: Clover Biopharmaceuticals USA, LLC

Sex: All·Age: 60 - 85·Accepts healthy volunteers

Code: NCT06843317·Phase 1·Recruiting

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A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

for MTAP-deleted Solid Tumors

17 locations incl. Birmingham

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06914128·Phase 1, Phase 2·Recruiting

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A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)

for Renal Cell Carcinoma, Clear Cell

Drug: Ipilimumab

6 locations incl. Boston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06708949·Phase 2·Recruiting

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Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

for Breast Neoplasms

8 locations incl. Santa Monica

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06797635·Phase 2·Recruiting

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A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

for Solid Tumor

13 locations incl. Denver

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06874335·Phase 1·Recruiting

Apply to this trial