Paid Clinical Trials in Tennessee

Tennessee has 2,076 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,847 clinical trials

A Study of CSTI-500 in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

1 location in Nashville

Sponsor: ConSynance Therapeutics

Sex: All·Age: 13 - 50

Code: NCT07348601·Phase 2·Recruiting·Listed Jan 2026

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A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

for TP53 Y220C Mutation

Drug: rezatapopt

Sites in Nashville +4 more locations

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 18+

Code: NCT07372625·Phase 1·Recruiting·Listed Jan 2026

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DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

for Transthyretin Amyloidosis With Cardiomyopathy

Sites in Memphis +3 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07358078·Recruiting·Listed Jan 2026

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A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

for Locally Advanced or Metastatic Malignant Solid Tumors

Sites in Nashville +3 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07287995·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Study in Advanced Solid Tumor Patients

for Advanced Solid Tumor

Sites in Nashville +4 more locations

Sponsor: Callio Therapeutics

Sex: All·Age: 18+

Code: NCT07300943·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for Renal Cell Carcinoma

Sites in Knoxville +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07227402·Phase 3·Recruiting·Listed Nov 2025

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A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for Advanced Solid Tumor, Adult

Sites in Nashville +5 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07361562·Phase 1·Recruiting·Listed Jan 2026

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A Study of BI 3810944 in Patients With Advanced Cancer

for Solid Tumours

Sites in Nashville +3 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07224425·Phase 1·Recruiting·Listed Nov 2025

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A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.

for Ankle Arthrodesis or Arthroplasty

Sites in Chattanooga +5 more locations

Sponsor: Kuros Biosurgery AG

Sex: All·Age: 18 - 75

Code: NCT07225751·Recruiting·Listed Nov 2025

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Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

for Lymphoma Diffuse Large B-cell

Sites in Nashville +4 more locations

Sponsor: AvenCell Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07284433·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

for Advanced Solid Tumor

Sites in Nashville +5 more locations

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT07213830·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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TLN-372 in Advanced KRAS Mutant Solid Tumors

for KRAS Mutant Solid Tumors

Sites in Nashville +5 more locations

Sponsor: Treeline Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07204340·Phase 1·Recruiting·Listed Oct 2025

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A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

for Solid Tumors

Sites in Nashville +7 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07195916·Phase 1·Recruiting·Listed Sep 2025

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Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability

for Smoking Behaviors

Sites in Knoxville +1 more location

Sponsor: JT International SA

Sex: All·Age: 22 - 65·Accepts healthy volunteers

Code: NCT07476144·Phase 1·Recruiting·Listed Mar 2026

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Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

for Leukemia, Myeloid, Acute

Sites in Nashville +5 more locations

Sponsor: Orca Biosystems, Inc.

Sex: All·Age: 18+

Code: NCT07216443·Phase 2·Recruiting·Listed Oct 2025

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Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

for Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Sites in Nashville +7 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07140900·Phase 1·Recruiting·Listed Aug 2025

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A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

for Renal Cell Carcinoma

Drug: BMS-986506

Sites in Nashville +4 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07195682·Phase 1·Recruiting·Listed Sep 2025

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A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors

for Colorectal Neoplasms

Sites in Nashville +3 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07107230·Phase 1·Recruiting·Listed Aug 2025

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Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

for Skin Laxity (Submental and Neck)

Sites in Nashville +4 more locations

Sponsor: CLASSYS Inc.

Sex: All·Age: 30 - 65·Accepts healthy volunteers

Code: NCT07229430·Recruiting·Listed Nov 2025

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This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

for Non-Hodgkin Lymphoma Refractory/ Relapsed

Sites in Nashville +5 more locations

Sponsor: LTZ Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07121946·Phase 1·Recruiting·Listed Aug 2025

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TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas

for Lymphoma

Sites in Nashville +7 more locations

Sponsor: Treeline Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07082803·Phase 1·Recruiting·Listed Jul 2025

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Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

for Hemophilia B

Sites in Memphis +4 more locations

Sponsor: CSL Behring

Sex: Male·Age: 138 Months - 206 Months

Code: NCT07080905·Phase 3·Recruiting·Listed Jul 2025

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A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

for Non Small Cell Lung Cancer

Sites in Nashville +8 more locations

Sponsor: Compass Therapeutics

Sex: All·Age: 18+

Code: NCT06150664·Phase 1·Recruiting·Listed Nov 2023

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A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

for Breast Cancer

Sites in Germantown +3 more locations

Sponsor: Hoffmann-La Roche

Sex: Female·Age: 18+

Code: NCT07054190·Phase 2·Recruiting·Listed Jul 2025

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Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN)

for Osteogenesis Imperfecta (OI)

Sites in Nashville +8 more locations

Sponsor: Angitia Incorporated Limited

Sex: All·Age: 18 - 75

Code: NCT07062588·Phase 2·Recruiting·Listed Jul 2025

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Virtue® SAB in the Treatment of Coronary ISR Trial

for Coronary Artery Disease

Sites in Nashville +14 more locations

Sponsor: Orchestra BioMed, Inc

Sex: All·Age: 18+

Code: NCT07045194·Recruiting·Listed Jul 2025

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A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS)

for Multiple Sclerosis

Sites in Knoxville +8 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18 - 65

Code: NCT07074886·Phase 2·Recruiting·Listed Jul 2025

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First In Human Study of CX-2051 in Advanced Solid Tumors

for Solid Tumor, Adult

Sites in Nashville +7 more locations

Sponsor: CytomX Therapeutics

Sex: All·Age: 18+

Code: NCT06265688·Phase 1·Recruiting·Listed Feb 2024

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Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

for GEP-NET

Sites in Nashville +6 more locations

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT07165132·Phase 1·Recruiting·Listed Sep 2025

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Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

for Metastatic Hepatocellular Carcinoma

Sites in Nashville +8 more locations

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06915753·Phase 1·Recruiting·Listed Apr 2025

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First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

for Advanced Solid Tumors

Sites in Nashville +5 more locations

Sponsor: Accent Therapeutics

Sex: All·Age: 18+

Code: NCT06799065·Phase 1·Recruiting·Listed Jan 2025

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A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

for Metastatic Hepatocellular Carcinoma

Drug: Bevacizumab

Sites in Nashville +6 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06427941·Phase 1·Recruiting·Listed May 2024

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Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for Diffuse Astrocytoma, IDH-Mutant

Sites in Nashville +6 more locations

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06047379·Phase 1, Phase 2·Recruiting·Listed Sep 2023

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Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

for Advanced HR+/HER2- Breast Cancer

Sites in Nashville +7 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06726148·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

for Hormone Receptor-positive Breast Cancer

Sites in Nashville +5 more locations

Sponsor: Ellipses Pharma

Sex: Female·Age: 18+

Code: NCT05573126·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Nashville +2 more locations

Sponsor: Nerviano Medical Sciences

Sex: All·Age: 18+

Code: NCT06931626·Phase 1·Recruiting·Listed Apr 2025

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Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

for Epithelial Ovarian Cancer

Sites in Chattanooga +7 more locations

Sponsor: Imunon

Sex: Female·Age: 18+

Code: NCT06915025·Phase 3·Recruiting·Listed Apr 2025

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A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours

for Advanced Solid Tumor

Sites in Nashville +4 more locations

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT06833008·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

for Castration-Resistant Prostatic Cancer

Sites in Germantown +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06863272·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors

for Solid Tumor

Sites in Nashville +4 more locations

Sponsor: Chugai Pharmaceutical

Sex: All·Age: 18+

Code: NCT05907980·Phase 1·Recruiting·Listed Jun 2023

Apply to this trial