Paid Clinical Trials in Tennessee

Tennessee has 2,157 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,157 clinical trials

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A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

for Pneumococcal Disease

58 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 42 Days - 211 Days·Accepts healthy volunteers

Code: NCT07629440·Phase 3·Recruiting

Apply to this trial

A Phase 1 Study of the Safety and Tolerability of CTX-10726

for Gastroesophageal Cancer (GC)

Drug: CTX-10726

5 locations incl. Boston

Sponsor: Compass Therapeutics

Sex: All·Age: 18+

Code: NCT07419841·Phase 1·Recruiting

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A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

for ER-Positive HER2-Negative Breast Cancer

Drug: Camizestrant

12 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07647328·Phase 3·Not Yet Recruiting

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndrome

24 locations incl. Gilbert

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07422480·Phase 3·Recruiting

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A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

for Obesity

Drug: Semaglutide

99 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07564414·Phase 3·Recruiting

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Feasibility and Safety of Single-Port Robotic-Assisted Deep Inferior Epigastric Pedicle Flap Harvest

for DIEP Flap Breast Reconstruction

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+

Code: NCT07222514·Recruiting

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A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

3 locations incl. Palo Alto

Sponsor: AbbVie

Sex: All·Age: 6 Months - 17

Code: NCT07306832·Phase 1·Recruiting

Apply to this trial

Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

for Major Depressive Disorder

25 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06705478·Phase 2·Recruiting

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Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS)

for Lumbar Puncture

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 1 Day - 12 Months

Code: NCT07612644·Recruiting

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Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

8 locations incl. Orange

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 60+

Code: NCT06773936·Phase 2·Enrolling By Invitation

2-HOBA in Systemic Lupus Erythematosus

for Systemic Lupus Erthematosus (SLE)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+

Code: NCT07225543·Phase 2·Recruiting

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An Open-Label Study to Evaluate PF-07994525 in Participants With Advanced Cancers

for Advanced Malignancies

4 locations incl. Nashville

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07426757·Phase 1·Recruiting

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PrP-targeting siRNA Safety & Mechanism Study

for Prion Disease

5 locations incl. Boston

Sponsor: Broad Institute of MIT and Harvard

Sex: All·Age: 18+

Code: NCT07444580·Phase 1·Recruiting

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A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

for Alzheimer's Disease

10 locations incl. Irvine

Sponsor: AbbVie

Sex: All·Age: 50 - 90

Code: NCT07599670·Phase 1, Phase 2·Recruiting

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Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

for Type 1 Diabetes Mellitus

2 locations incl. Pittsburgh

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 8 - 45

Code: NCT07142252·Phase 2·Recruiting

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AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

for Hernia

12 locations incl. Loma Linda

Sponsor: Tissium

Sex: All·Age: 22+

Code: NCT07277946·Recruiting

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Early Signals of the Transition From Immune Quiescence to Activation in the Liver Allograft Microenvironment and in the Circulation

for Liver Transplant

10 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 13

Code: NCT07549503·Phase 2·Recruiting

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A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

for Diabetic Macular Edema

30 locations incl. Phoenix

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07553429·Phase 1, Phase 2·Recruiting

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Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for Atypical Teratoid/Rhabdoid Tumor

10 locations incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 26

Code: NCT06465199·Phase 1, Phase 2·Recruiting

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Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

for Ovarian Cancer

5 locations incl. Peoria

Sponsor: Nerviano Medical Sciences

Sex: Female·Age: 18+

Code: NCT06930755·Phase 1·Recruiting

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Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

for Locally Advanced Pancreatic Adenocarcinoma

274 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06998940·Phase 3·Recruiting

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Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica

for Polymyalgia Rheumatica

9 locations incl. Denver

Sponsor: Sanofi

Sex: All·Age: 50+

Code: NCT07286214·Phase 4·Recruiting

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Examination of Personalized SpO2 Targets

for Acute Respiratory Failure

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07536984·Enrolling By Invitation

A Study of TAK-505 in Adults With Solid Tumors

for Malignant Solid Tumors

15 locations incl. Orange

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07436728·Phase 1, Phase 2·Recruiting

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Study of INCA036978 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Drug: INCA036978

22 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07441694·Phase 1·Recruiting

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An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for Cardiovascular Disease and Lipoprotein(a)

Drug: Pelacarsen

115 locations incl. Andalusia

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07517263·Phase 3·Recruiting

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Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

for Urothelial Cancer

9 locations incl. Santa Barbara

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07566156·Phase 3·Recruiting

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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for Obesity

Drug: NNC0487-0111

202 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07567001·Phase 3·Not Yet Recruiting

A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

for Overweight

48 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07575932·Phase 2·Recruiting

Apply to this trial

Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis

for Liver Fibrosis

19 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07610837·Phase 2·Recruiting

Apply to this trial

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

for Solid Tumors

Drug: Adagrasib

17 locations incl. Phoenix

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07415031·Phase 2·Recruiting

Apply to this trial

Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer

for Advanced Breast Cancer

Drug: Camizestrant

3 locations incl. St Louis

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07427394·Phase 2·Recruiting

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Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

14 locations incl. Birmingham

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting

Apply to this trial

Impact of Pelvic Pain Podcast

for Chronic Pelvic Pain

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+

Code: NCT07568834·Recruiting

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A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

for Non-small Cell Lung Cancer

5 locations incl. Billings

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07513376·Phase 3·Recruiting

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AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

24 locations incl. Dothan

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting

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Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

for High Grade Glioma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 3

Code: NCT06528691·Phase 2·Recruiting

Apply to this trial

Mode of Ventilation During Critical Illness at Multiple Centers

for Respiratory Failure

4 locations incl. Chicago

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07313956·Enrolling By Invitation

Investigation of the Delve Detect Cerebrospinal Fluid (CSF) Metagenomic Next-generation Sequencing (mNGS) Test When Used for the Initial Diagnostic Workup of Patients With Suspected Central Nervous System (CNS) Infection

for Central Nervous System Infection

3 locations incl. San Francisco

Sponsor: Delve Bio, Inc.

Sex: All·Age: All ages

Code: NCT07435649·Recruiting

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A Study in People With Advanced Cancer to Test How Well Different Doses of BI 3819026 Are Tolerated When Taken Alone and Together With Ezabenlimab

for Advanced Solid Cancer

4 locations incl. New Haven

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07607678·Phase 1·Recruiting

Apply to this trial