Paid Clinical Trials in Tennessee

Tennessee has 2,076 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,847 clinical trials

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

Sites in Memphis +18 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting·Listed Feb 2024

Apply to this trial

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 6 - 25

Code: NCT03353584·Recruiting·Listed Nov 2017

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Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans

for Endothelial Dysfunction

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT04769206·Phase 1, Phase 2·Recruiting·Listed Feb 2021

Apply to this trial

Revealing Information Genuinely & Honestly Across Time - Communication Preferences Visit

for Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT06993688·Recruiting·Listed May 2025

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Single Versus Dual Implant Fixation of Distal Femur Fractures

for Articular Fractures

Sites in Nashville +15 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06286670·Recruiting·Listed Feb 2024

Apply to this trial

Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

Sites in Nashville +25 more locations

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting·Listed Jul 2022

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Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

for Breast Cancer

Sites in Chattanooga +14 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04468061·Phase 2·Recruiting·Listed Jul 2020

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CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions

for B-Cell Acute Lymphoblastic Leukemia (B-ALL)

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT07048535·Recruiting·Listed Jul 2025

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Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

for Breast Cancer

Sites in Nashville +6 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT05748834·Phase 2·Recruiting·Listed Mar 2023

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Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for Stage III Ovarian Cancer

Drug: Niraparib

Sites in Nashville +58 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05659381·Phase 3·Recruiting·Listed Dec 2022

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Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

for Neuroblastoma

Sites in Nashville +11 more locations

Sponsor: Giselle Sholler

Sex: All·Age: 1 - 21

Code: NCT06540963·Phase 2·Recruiting·Listed Aug 2024

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Early Use of Long-acting Tacrolimus in Lung Transplant Recipients

for Lung Transplant

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT04469842·EARLY_Phase 1·Recruiting·Listed Jul 2020

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OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

for Cardiac Failure

Sites in Nashville +6 more locations

Sponsor: Inova Health Care Services

Sex: All·Age: 18 - 99

Code: NCT06939751·Recruiting·Listed Apr 2025

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Cabozantinib for Patients With Recurrent or Progressive Meningioma

for Meningioma

Drug: Cabozantinib

Sites in Nashville +2 more locations

Sponsor: Baptist Health South Florida

Sex: All·Age: 18+

Code: NCT05425004·Phase 2·Recruiting·Listed Jun 2022

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Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

for Orthopaedic Trauma

Sites in Nashville +1 more location

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06201676·Phase 4·Recruiting·Listed Jan 2024

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Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

for Lung Cancer

2 locations in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT00898313·Recruiting·Listed May 2009

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Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

for High Grade Glioma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 3

Code: NCT06528691·Phase 2·Recruiting·Listed Jul 2024

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High-Resolution PET-CT Imaging for Surgical Margin Visualization

for Cancer

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT06915454·Recruiting·Listed Apr 2025

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Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

for Fracture of Tibia

Sites in Nashville +5 more locations

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18+

Code: NCT06337292·Phase 3·Recruiting·Listed Mar 2024

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Clinical Outcomes of the ALPS Proximal Humerus Plating System

for Proximal Humeral Fracture

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT03328650·Recruiting·Listed Nov 2017

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Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck

for Aortic Aneurysm, Abdominal

Sites in Kingsport +15 more locations

Sponsor: Rijnstate Hospital

Sex: All·Age: 18+

Code: NCT05484115·Recruiting·Listed Aug 2022

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Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

Sites in Nashville +5 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05422794·Phase 1·Recruiting·Listed Jun 2022

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Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases

for Neurodegenerative Diseases

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 50 - 85·Accepts healthy volunteers

Code: NCT05357612·Phase 4·Recruiting·Listed May 2022

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Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

for Locally Advanced Cancer

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT06828588·EARLY_Phase 1·Recruiting·Listed Feb 2025

Apply to this trial

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

for Drug Allergy

Sites in Nashville +5 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06406114·Phase 2·Recruiting·Listed May 2024

Apply to this trial

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

Sites in Nashville +22 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting·Listed Jun 2024

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in Nashville +27 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting·Listed Feb 2023

Apply to this trial

Retinoblastoma Patient Clinical Database and Tissue Repository

for Retinoblastoma

Sites in Memphis +7 more locations

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 0 - 18

Code: NCT04959097·Recruiting·Listed Jul 2021

Apply to this trial

Swallowing Impairments in Adults With and Without Alzheimer's Disease

for Alzheimer Disease

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06678100·Recruiting·Listed Nov 2024

Apply to this trial

Retinal Vascular Changes During Pregnancy

for Pregnancy

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+

Code: NCT06311617·Recruiting·Listed Mar 2024

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(89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma

for Head and Neck Squamous Cell Carcinoma

1 location in Nashville

Sponsor: Eben Rosenthal

Sex: All·Age: 19+

Code: NCT05747625·Phase 1·Recruiting·Listed Feb 2023

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High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

for Immunization

Sites in Nashville +7 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 17

Code: NCT05947071·Phase 2·Recruiting·Listed Jul 2023

Apply to this trial

Volatility in Paranoia (VIP) Trial: An RCT of Changes in Volatility With Psychotherapy

for Schizophrenia Disorders

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65

Code: NCT06835556·Recruiting·Listed Feb 2025

Apply to this trial

Effects of Acute Sugar Intake on Choroidal Thickness

for Choroid

1 location in Memphis

Sponsor: Southern College of Optometry

Sex: All·Age: 21 - 35·Accepts healthy volunteers

Code: NCT07376005·Recruiting·Listed Jan 2026

Apply to this trial

Effect of Giving Reduced Fluid in Children After Trauma

for Critical Illness

Sites in Memphis +3 more locations

Sponsor: Columbia University

Sex: All·Age: 6 Months - 15

Code: NCT04201704·Recruiting·Listed Dec 2019

Apply to this trial

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

for AL Amyloidosis

Drug: Belantamab mafodotin

Sites in Nashville +2 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT05145816·Phase 1, Phase 2·Recruiting·Listed Dec 2021

Apply to this trial

Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 8+·Accepts healthy volunteers

Code: NCT05810181·Recruiting·Listed Apr 2023

Apply to this trial

Respiratory Strength Training in Heart Transplant Recipients

for Dysphagia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 90

Code: NCT06190171·Recruiting·Listed Jan 2024

Apply to this trial

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18 - 21·Accepts healthy volunteers

Code: NCT05583721·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for Metastatic Malignant Neoplasm in the Liver

Sites in Memphis, Knoxville +378 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05040360·Phase 2·Recruiting·Listed Sep 2021

Apply to this trial