Paid Clinical Trials in Walnut Creek, CA

As of September 2026, 186 paid clinical trials are recruiting in Walnut Creek, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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175 clinical trials

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A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

for Chronic Migraine

Drug: Atogepant

Sites in Walnut Creek, San Jose +27 more locations

Sponsor: AbbVie

Sex: All·Age: 12 - 17

Code: NCT06810505·Phase 3·Recruiting·Listed Feb 2025

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A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

for Plaque Psoriasis

Drug: Deucravacitinib

Sites in Walnut Creek, Fremont +42 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 12 - 17

Code: NCT06979453·Phase 3·Recruiting·Listed May 2025

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A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

for Asthma

Drug: PF-07275315

Sites in Walnut Creek, San Jose +33 more locations

Sponsor: Pfizer

Sex: All·Age: 18 - 70

Code: NCT06977581·Phase 2·Recruiting·Listed May 2025

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A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

for Psychotic Disorders

Sites in Walnut Creek, Anaheim +15 more locations

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 55+

Code: NCT06540833·Phase 2·Recruiting·Listed Aug 2024

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A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

Sites in Walnut Creek, San Jose +28 more locations

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT07115329·Phase 2·Recruiting·Listed Aug 2025

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Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

Sites in Walnut Creek, Los Angeles +19 more locations

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT06547489·Phase 2·Recruiting·Listed Aug 2024

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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for High Risk Cardiovascular Disease

Drug: Zilebesiran

Sites in Walnut Creek, San Ramon +266 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07181109·Phase 3·Recruiting·Listed Sep 2025

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CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

for Type 1 Diabetes Mellitus

Sites in Walnut Creek, Newport Beach +43 more locations

Sponsor: COUR Pharmaceutical Development Company, Inc.

Sex: All·Age: 12 - 35

Code: NCT06783309·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

for Alzheimer Disease

Drug: KarXT

Sites in Walnut Creek, Fresno +31 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT07011732·Phase 3·Recruiting·Listed Jun 2025

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A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

for Alzheimer Disease

Drug: KarXT

Sites in Walnut Creek, Fresno +39 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT06937229·Phase 3·Recruiting·Listed Apr 2025

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A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

for Menstrual Migraine

Drug: Rimegepant

Sites in Walnut Creek, Canoga Park +30 more locations

Sponsor: Pfizer

Sex: Female·Age: 18 - 45

Code: NCT06641466·Phase 3·Recruiting·Listed Oct 2024

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A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

for Episodic Migraine

Drug: Atogepant

Sites in Walnut Creek, San Jose +25 more locations

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05711394·Phase 3·Recruiting·Listed Feb 2023

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A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

Sites in Walnut Creek, Orange +7 more locations

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05511363·Phase 3·Recruiting·Listed Aug 2022

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Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

Sites in Walnut Creek, Oakland +59 more locations

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07085767·Phase 3·Recruiting·Listed Jul 2025

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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

for Generalized Anxiety Disorder (GAD)

Sites in Walnut Creek, Los Angeles +45 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06846320·Phase 2·Recruiting·Listed Feb 2025

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Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sites in Walnut Creek, Encino +21 more locations

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18+

Code: NCT06701903·Phase 2·Recruiting·Listed Nov 2024

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Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

Sites in Walnut Creek, Los Angeles +84 more locations

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05980949·Phase 3·Recruiting·Listed Aug 2023

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A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting

for Pneumonia

Sites in Walnut Creek, Oakland +37 more locations

Sponsor: Pfizer

Sex: All·Age: 65+

Code: NCT05452941·Recruiting·Listed Jul 2022

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Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

for Neovascular Age-Related Macular Degeneration (nAMD)

Sites in Walnut Creek, Mountain View +52 more locations

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT07064759·Phase 3·Recruiting·Listed Jul 2025

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A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

for Hypothyroidism

Sites in Walnut Creek, Concord +128 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06345339·Phase 2, Phase 3·Recruiting·Listed Apr 2024

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A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

for Major Depressive Disorder

Sites in Walnut Creek, Glendale +41 more locations

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT06775379·Phase 3·Recruiting·Listed Jan 2025

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Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

for Major Depressive Disorder

Sites in Walnut Creek, San Jose +30 more locations

Sponsor: Autobahn Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06633016·Phase 2·Recruiting·Listed Oct 2024

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Study of EVO756 in Adults With Migraine

for Migraine

Sites in Walnut Creek, Fresno +24 more locations

Sponsor: Evommune, Inc.

Sex: All·Age: 18 - 64

Code: NCT07616128·Phase 2·Recruiting·Listed Jun 2026

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A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

for Obesity

Sites in Walnut Creek, Sacramento +32 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07595549·Phase 3·Recruiting·Listed May 2026

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Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

for Diabetic Retinopathy

Drug: Surabgene Lomparvovec

Sites in Walnut Creek, Mountain View +30 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07592273·Phase 2, Phase 3·Recruiting·Listed May 2026

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A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

for Depressive Disorder, Major

Drug: Seltorexant

Sites in Walnut Creek, Glendale +29 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 74

Code: NCT07573176·Phase 3·Recruiting·Listed May 2026

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Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

for Obesity

Sites in Walnut Creek +10 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07607587·Phase 1·Recruiting·Listed May 2026

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AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

Sites in Walnut Creek, Lomita +12 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

Continuous Dual Aspiration Technique With Zoom System for Stroke

for Ischemic Stroke

Sites in Walnut Creek +16 more locations

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07491952·Recruiting·Listed Mar 2026

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A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for Obesity

Drug: NNC0487-0111

Sites in Walnut Creek +18 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07481630·Phase 3·Recruiting·Listed Mar 2026

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A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

for Diabetes Mellitus, Type 2

Drug: NNC0662-0419

Sites in Walnut Creek, Lancaster +21 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18 - 75

Code: NCT07415954·Phase 2·Recruiting·Listed Feb 2026

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A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

for Diabetic Macular Edema

Drug: RO7823653

Sites in Walnut Creek, Beverly Hills +10 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07425522·Phase 1·Recruiting·Listed Feb 2026

Apply to this trial

Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)

for Hereditary Angioedema (HAE)

Sites in Walnut Creek, San Diego +13 more locations

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07428499·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial

A Study to Learn About mRNA Vaccines Against Influenza in Adults

for Healthy Adults

Sites in Walnut Creek +14 more locations

Sponsor: Pfizer

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07431853·Phase 2·Recruiting·Listed Feb 2026

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A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

for Ovarian Neoplasms

Sites in Walnut Creek +25 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT07318558·Phase 3·Recruiting·Listed Jan 2026

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A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

for Nausea

Sites in Walnut Creek, Los Alamitos +19 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07169851·Phase 2·Recruiting·Listed Sep 2025

Apply to this trial

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

for Clonal Mast Cell Disease

Sites in Walnut Creek, San Diego +20 more locations

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT07143669·Recruiting·Listed Aug 2025

Apply to this trial

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

for Macular Telangiectasia Type 2 (MacTel)

Sites in Walnut Creek, Palo Alto +21 more locations

Sponsor: Neurotech Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06971939·Phase 4·Recruiting·Listed May 2025

Apply to this trial

STOP-HAE: A Phase 3 Study of ADX-324 in HAE

for Hereditary Angioedema

Sites in Walnut Creek, Santa Monica +15 more locations

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06960213·Phase 3·Recruiting·Listed May 2025

Apply to this trial

HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs

for Degenerative Disc Disease (DDD)

Sites in Walnut Creek, Santa Monica +12 more locations

Sponsor: ReGelTec, Inc.

Sex: All·Age: 22 - 85

Code: NCT06011551·Recruiting·Listed Aug 2023

Apply to this trial