Paid Clinical Trials in Wilmington, DE

As of September 2026, 137 paid clinical trials are recruiting in Wilmington, Delaware. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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129 clinical trials

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Pediatricians Building Resilience Through Early Identification for Toddler Well-Being

for Mental Health

1 location in Wilmington

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07091240·Recruiting·Listed Jul 2025

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Transdisciplinary Care for Young Adults With Type 1 Diabetes

for Type 1 Diabetes

Sites in Wilmington +1 more location

Sponsor: Nemours Children's Clinic

Sex: All·Age: 17+

Code: NCT06172166·Recruiting·Listed Dec 2023

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Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in Wilmington, Newark +392 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: All ages

Code: NCT04242095·Recruiting·Listed Jan 2020

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Wilmington +141 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Gastroschisis Outcomes of Delivery (GOOD) Study

for Gastroschisis

Sites in Wilmington +35 more locations

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT02774746·Recruiting·Listed May 2016

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Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

Sites in Wilmington, Newark +373 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting·Listed Jun 2025

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Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

for Sickle Cell Disease (SCD)

Sites in Wilmington +30 more locations

Sponsor: University of Rochester

Sex: All·Age: 3 - 20

Code: NCT06941389·Recruiting·Listed Apr 2025

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Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA)

for Sickle Cell Disease

1 location in Wilmington

Sponsor: Nemours Children's Clinic

Sex: All·Age: 15+

Code: NCT05383911·Recruiting·Listed May 2022

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Wilmington, Newark +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Wilmington +59 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

for Severe Sickle Cell Disease

Sites in Wilmington +3 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 1 Day - 21

Code: NCT03128996·Phase 1, Phase 2·Recruiting·Listed Apr 2017

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LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for Advanced Colorectal Carcinoma

Sites in Wilmington, Newark +194 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06073431·Recruiting·Listed Oct 2023

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Non-invasive Functional Assessment and Pathogenesis of Morquio A

for Mucopolysaccharidosis IV Type A

1 location in Wilmington

Sponsor: Nemours Children's Clinic

Sex: All·Age: All ages

Code: NCT05284006·Recruiting·Listed Mar 2022

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A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

for Anemia, Sickle Cell

Sites in Wilmington +3 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 21

Code: NCT06290401·Recruiting·Listed Mar 2024

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Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

for Colorectal Cancer

Sites in Wilmington, Newark +140 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 60+

Code: NCT03998202·Recruiting·Listed Jun 2019

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Precise Infliximab Exposure and Pharmacodynamic Control

for Crohn Disease

Sites in Wilmington +10 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 6 - 22

Code: NCT05660746·Phase 2, Phase 3·Recruiting·Listed Dec 2022

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Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

for Castration-Resistant Prostate Carcinoma

Sites in Wilmington, Newark +172 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT06470243·Phase 3·Recruiting·Listed Jun 2024

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Wilmington +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in Wilmington +27 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting·Listed Feb 2023

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Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

for Failed or Difficult Intubation, Sequela

Sites in Wilmington +50 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02493478·Recruiting·Listed Jul 2015

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Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

Sites in Wilmington +19 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting·Listed Aug 2025

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Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for Cystic Fibrosis

Sites in Wilmington +17 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06683092·Recruiting·Listed Nov 2024

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Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

for Sickle Cell Trait

Sites in Wilmington +9 more locations

Sponsor: National Alliance for Sickle Cell Centers

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06071377·Recruiting·Listed Oct 2023

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Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

Sites in Wilmington +39 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting·Listed Mar 2016

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

Sites in Wilmington +108 more locations

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting·Listed Apr 2025

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

Sites in Wilmington, Newark +586 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting·Listed May 2021

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Pilot Trial Assessing the Effectiveness of Laser Hair Depilation on Pilonidal Disease Recurrence in Patients With Darker Skin Color

for Pilonidal Disease

1 location in Wilmington

Sponsor: Nemours Children's Clinic

Sex: All·Age: 10 - 21

Code: NCT06406621·Recruiting·Listed May 2024

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Non-Invasive Respiratory Monitor

for Neuromuscular Diseases

1 location in Wilmington

Sponsor: Nemours Children's Clinic

Sex: All·Age: 11 - 17·Accepts healthy volunteers

Code: NCT02851043·Recruiting·Listed Aug 2016

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Primordial Dwarfism Registry

for MOPDII

1 location in Wilmington

Sponsor: Nemours Children's Clinic

Sex: All·Age: All ages

Code: NCT04569149·Recruiting·Listed Sep 2020

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The Pediatric Anesthesia Quality Improvement Project

for Surgery

Sites in Wilmington +36 more locations

Sponsor: The Society for Pediatric Anesthesia

Sex: All·Age: Up to 21

Code: NCT00674388·Recruiting·Listed May 2008

Apply to this trial

Disclosure Intervention for People in Treatment for Opioid Use Disorder

for Opioid Use Disorder

1 location in Wilmington

Sponsor: University of Delaware

Sex: All·Age: 18+

Code: NCT06458985·Recruiting·Listed Jun 2024

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Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

Sites in Wilmington +21 more locations

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting·Listed Dec 2025

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Chronic Postsurgical Pain

for Cerebral Palsy

Sites in Wilmington +1 more location

Sponsor: Chantel Burkitt

Sex: All·Age: 5 - 17

Code: NCT05764681·Recruiting·Listed Mar 2023

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Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis

for Scoliosis

Sites in Wilmington +3 more locations

Sponsor: St. Justine's Hospital

Sex: All·Age: 10 - 15

Code: NCT02434003·Recruiting·Listed May 2015

Apply to this trial

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

Sites in Wilmington +58 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting·Listed Aug 2016

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Stress Hydrocortisone In Pediatric Septic Shock

for Septic Shock

Sites in Wilmington +17 more locations

Sponsor: Jerry Zimmerman

Sex: All·Age: 1 Month - 17

Code: NCT03401398·Phase 3·Recruiting·Listed Jan 2018

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Cough Management Wellness App for Refractory or Unexplained Chronic Cough

for Refractory Chronic Cough

1 location in Wilmington

Sponsor: Hyfe Inc

Sex: All·Age: 21+

Code: NCT07070895·Recruiting·Listed Jul 2025

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The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

for B-cell Acute Lymphoblastic Leukemia

Sites in Wilmington +23 more locations

Sponsor: Pediatric Transplantation & Cellular Therapy Consortium

Sex: All·Age: 1 - 25

Code: NCT03509961·Phase 2·Recruiting·Listed Apr 2018

Apply to this trial

Percepta for Cognitive Optimization

for Mild Cognitive Impairment (MCI)

1 location in Wilmington

Sponsor: Cerebrum DAO Association

Sex: All·Age: 40 - 85

Code: NCT07612449·Recruiting·Listed May 2026

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A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

for Rhabdomyosarcoma

Sites in Wilmington +84 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT07466316·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial