Comparative Trial for Pixantrone in Combination With Rituximab in Indolent Non-Hodgkin's Lymphoma

Part of paid clinical trials in Tucson, Arizona.

Sponsor
CTI BioPharma
Study ID
NCT00060671
Phase
PHASE3
Status
Terminated

Conditions

  • Lymphoma, Follicular
  • Lymphoma, Low-Grade
  • Lymphoma, Mixed-Cell, Follicular
  • Lymphoma, Small Cleaved-Cell, Follicular

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • rituximab — DRUG
  • Pixantrone (BBR 2778) — DRUG

Study Details

The purpose of this study is to determine whether combining pixantrone (BBR 2778, INN name pending) with the monoclonal antibody rituximab, leads to an increase in the period of patients' remission, compared to rituximab alone.

Key Dates

Start date
Jan 31, 2005
Status verified
May 2013
Primary completion
Jan 31, 2006
Completion
Jan 31, 2006

Study Design

Enrollment
800 participants
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Primary Outcome Measure

Compare the time to tumor progression (TTP) of the combination of BBR 2778 (pixantrone) + rituximab with that of rituximab alone [ Time Frame: For 5 years post treatment ]

Locations (38)

FacilityCityStateZIPSite coordinators
Arizona Clinical Research CenterTucsonArizona85712-
Sutter Health Western Division Cancer Research GroupGreenbraeCalifornia94904-
Kenmar Research InstituteLos AngelesCalifornia90057-
Rocky Moutain Cancer CenterDenverColorado80218-
Pasco, Hernando Oncology Associates, P.A.New Port RicheyFlorida--
Ocala Oncology CenterOcalaFlorida34474-
Orange Park Cancer CenterOrange ParkFlorida32073-
Illinois Masonic Cancer CenterChicagoIllinois60657-
University of Chicago Medical Center Hematology / OncologyChicagoIllinois60637-
Edward Cancer CenterNapervilleIllinois60540-
Hope CenterTerre HauteIndiana47802-
Commonwealth Hematology/OncologyDanvilleKentucky40422-
New England Hematology / Oncology AssociatesWellesleyMassachusetts02481-
St. Joseph OncologySaint JosephMissouri64507-
Christian HospitalSt LouisMissouri63136-
St. Johns Mercy Medical CenterSt LouisMissouri63141-
Hematology - Oncology Centers of N. RockiesBillingsMontana59101-
Great Falls ClinicGreat FallsMontana59405-
East Orange VA Medical CenterEast OrangeNew Jersey07018-
Hematology Oncology Associates of NJParamusNew Jersey07652-
Summit Medical Group/Overlook Onc CenterSummitNew Jersey07901-
New Mexico Oncology / HematologyAlbuquerqueNew Mexico87109-
HemOnCare, P.C.BrooklynNew York11235-
Glens Falls Cancer CenterGlens FallsNew York12801-
North Shore - Long Island Jewish Health SystemNew Hyde ParkNew York11040-
New York UniversityNew YorkNew York10016-
Upstate NY Cancer ResearchRochesterNew York14623-
South Shore Hematology-Oncology AssociatesRockville CentreNew York11570-
Clinworks, IncCharlotteNorth Carolina--
Private PracticeCantonOhio44718-
Blair Medical AssociatesAltoonaPennsylvania16601-
Lancaster Cancer Center, LTDLancasterPennsylvania17605-
Santee Hematology OncologySumterSouth Carolina29150-
The West ClinicMemphisTennessee38120-
Central Utah Medical Clinic Hematology-OncologyProvoUtah84604-
Oncology of WisconsinGlendaleWisconsin53212-
Marshfield ClinicMarshfieldWisconsin54449-
Rhinelander Regional Medical Group Onc.RhinelanderWisconsin54501-

Find similar trials in Tucson, AZ

By research site
Arizona Clinical Research Center· Tucson, AZSutter Health Western Division Cancer Research Group· Greenbrae, CAKenmar Research Institute· Los Angeles, CARocky Moutain Cancer Center· Denver, COPasco, Hernando Oncology Associates, P.A.· New Port Richey, FLOcala Oncology Center· Ocala, FL

Related Studies