A Study Evaluating Tarceva in Combination With Avastin Versus Avastin Alone in Treating Metastatic Renal Cell Carcinoma

Part of paid clinical trials in Concord, California.

Sponsor
Genentech, Inc.
Study ID
NCT00081614
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The primary purpose of the study is to assess the potential benefit of combining two targeted therapies (an anti-EGF inhibitor along with an anti-VEGF inhibitor). The goal will be to determine whether the addition of Erlotinib to Avastin will improve the benefit in metastatic renal cell carcinoma (RCC) with regard to time to progression, response rate, duration of response, and survival compared with Avastin alone. Since Avastin has been shown to be active in renal cancer, the goal will be to assess whether this activity can be enhanced with Erlotinib.

Key Dates

First listed
Apr 20, 2004
Start date
Mar 31, 2004
Status verified
May 2014
Completion
Jul 31, 2005

Study Design

Enrollment
100 participants
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Locations (20)

FacilityCityStateZIPSite coordinators
Bay Area Cancer Research GroupConcordCalifornia94520-
UCLA School of MedicineLos AngelesCalifornia90095-
Kaiser Permanente Medical GroupSan DiegoCalifornia92120-
Stanford University Medical CenterStanfordCalifornia94305-
UCHSC - Urologic OncologyAuroraColorado80010-
Bennett Cancer CenterStamfordConnecticut06902-
Lynn Regional Cancer Center - WestBoca RatonFlorida33428-
Ochsner Cancer InstituteNew OrleansLouisiana70121-
Beth Israel Deaconess Medical CenterBostonMassachusetts02215-
Wayne State University / Harper University HospitalDetroitMichigan48201-
St. Joseph OncologySaint JosephMissouri64507-
The Cancer Center at Hackensack University Medical CenterHackensackNew Jersey07601-
North Shore University HospitalManhassetNew York11030-
NYU School of MedicineNew YorkNew York10016-
Our Lady of Mercy Medical CenterThe BronxNew York10466-
Northwestern Carolina Oncology & HematologyHickoryNorth Carolina28601-
Raleigh Hematology OncologyRaleighNorth Carolina27609-
The Cleveland ClinicClevelandOhio44195-
Fox Chase Cancer CenterPhiladelphiaPennsylvania19111-
University of PennsylvaniaPhiladelphiaPennsylvania19004-

Find similar trials in Concord, CA

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Kidney cancer
By specialty
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By research site
Bay Area Cancer Research Group· Concord, CAUCLA School of Medicine· Los Angeles, CAKaiser Permanente Medical Group· San Diego, CAStanford University Medical Center· Stanford, CAUCHSC - Urologic Oncology· Aurora, COBennett Cancer Center· Stamford, CT

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