Bevacizumab and Erlotinib in the Treatment of Patients With Carcinoma of Unknown Primary Site

Sponsor
SCRI Development Innovations, LLC
Study ID
NCT00193622
Phase
PHASE2
Status
Completed

Conditions

  • Neoplasms, Unknown Primary

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

This trial will investigate the combination of bevacizumab, and erlotinib in patients with adenocarcinoma or poorly differentiated carcinoma of unknown primary site. Bevacizumab and erlotinib are relatively well-tolerated and have non-overlapping toxicity profiles. This trial will be one of the first clinical trials to evaluate a combination of targeted agents in the treatment of a solid tumor.

Key Dates

First listed
Sep 19, 2005
Start date
Apr 30, 2004
Status verified
Sep 2010
Primary completion
Sep 30, 2005
Completion
Jan 31, 2009

Study Design

Enrollment
50 participants
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Primary Outcome Measure

Overall response rate