Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage

Sponsor
The George Institute
Study ID
NCT00226096
Status
Completed

Conditions

  • CVA (Cerebrovascular Accident)
  • Cerebral Hemorrhage
  • Intracranial Hemorrhages

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Labetalol Hydrochloride — DRUG
  • Metoprolol tartrate — DRUG
  • Hydralazine Hydrochloride — DRUG
  • Glycerol Trinitrate — DRUG
  • Phentolamine mesylate — DRUG
  • Nicardipine — DRUG
  • Urapidil — DRUG
  • Esmolol — DRUG
  • Clonidine — DRUG
  • Enalaprilat — DRUG
  • Nitroprusside — DRUG

Study Details

The purpose of the study is to determine whether lowering high blood pressure levels after the start of a stroke caused by bleeding in the brain (intracerebral haemorrhage) will reduce the chances of a person dying or surviving with a long term disability. The study will be undertaken in two phases: a vanguard phase in 400 patients, to plan for a main phase in 2000 patients.

Key Dates

Start date
Nov 30, 2005
Status verified
Jun 2008
Primary completion
Sep 30, 2007
Completion
Sep 30, 2007

Study Design

Enrollment
404 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Primary Outcome Measure

Combination death and dependency, according to a 3-6 scores on the modified Rankin Score. [ Time Frame: 3 months ]

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