A Pilot Study of the Use of Rituximab in the Treatment of Chronic Focal Encephalitis

Part of paid clinical trials in San Francisco, California.

Sponsor
California Pacific Medical Center Research Institute
Study ID
NCT00259805
Phase
PHASE1
Status
Completed

Conditions

  • Chronic Focal Encephalitis
  • Rasmussen's Encephalitis

Eligibility Criteria

Sex
ALL
Age
5 Years - 25 Years
Healthy Volunteers
Not accepted

Interventions

  • Rituximab — DRUG
    375 mg/m2 given as an IV infusion once weekly for four doses

Study Details

The purpose of this study is to assess the safety, tolerability and effectiveness of rituximab in the treatment of chronic focal encephalitis.

Key Dates

Start date
Jan 31, 2005
Status verified
Mar 2008
Primary completion
Dec 31, 2008
Completion
Dec 31, 2008

Study Design

Enrollment
10 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: IV Infusion

Primary Outcome Measure

To assess the safety and tolerability of Rituximab in the treatment of CFE. Adverse and serious adverse events during the study period, reasonably or probably related to Rituximab, will be assessed at each study visit up to 12 months. [ Time Frame: 12 months ]

Locations (1)

FacilityCityStateZIPSite coordinators
California Pacific Medical CenterSan FranciscoCalifornia94115-

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